Skip to main content

We bridge clinical research and basic science methods to understand Rare Diseases, and more specifically Neurodevelopmental Disorders.

We use clinical and molecular tools to perform deep phenotyping of patients, aiming at establishing trial ready cohorts for translational research.

Our basic science focuses on neurodevelopmental disorders caused by mutations in chromatin remodellers, large protein complexes controlling the “opening” of our genetic instruction book to allow reading by cellular machinery. We use in vitro models of human neurodevelopment to decipher the mechanisms of gene function in development and disease.

Student and postdoc queries are welcome. Please get in touch with Dr Cristina Dias if you’re interested in joining the lab.

Publications

    Additional Lab Members

    Alumni

    • Dr Oana Paun, PhD student (primary supervisor Dr Francois Guillemot, the Francis Crick Institute; currently Postdoctoral Research Associate)
    • Ms Kanisa Arunasalam, Research Assistant (Scientist, Engitex)
    • Mr Annishwara Ravindrasingham, iBSc student (MBBS student, King's College London)

    Collaborators

    Publications

      Additional Lab Members

      Alumni

      • Dr Oana Paun, PhD student (primary supervisor Dr Francois Guillemot, the Francis Crick Institute; currently Postdoctoral Research Associate)
      • Ms Kanisa Arunasalam, Research Assistant (Scientist, Engitex)
      • Mr Annishwara Ravindrasingham, iBSc student (MBBS student, King's College London)

      Collaborators

      Our Partners

      Wellcome trust

      Wellcome Trust

      Rosetrees Trust logo

      Rosetrees Trust

      The Crick logo

      The Francis Crick Institute

      GOSH

      Great Ormond Street Hospital for Children

      NIHR Logo

      National Institute for Health Research (NIHR)