Our research is aimed at understanding the mechanisms that regulate adhesion and migration in adherent cells. Adhesion is essential for development and homeostasis but also drives pathological states such as cancer, fibrosis and inflammation. Using 3D model systems, molecular biology and advanced microscopy approaches, we analyse how receptors convert signals from the extracellular environment to control cell behaviour. Our goal is to then translate this information into defining new targets for therapeutic intervention in cancer, skin disease and lung inflammation.
Current PhD students
Medical Research Council
Biotechnology & Biological Sciences Research Council
Breast Cancer Campaign