The Transplantation, Advanced Therapies & Regenerative Medicine theme brings together multidisciplinary biomedical expertise to harness the scientific strengths of the RW-ILS and the diversity of its clinical cases. The focus is on advancing both fundamental science and translational research in areas such as transplant immunology, liver genetics, stem cell biology, organ perfusion, and cell-based therapies.

Research groups within this theme are leading cutting-edge collaborative projects across King’s College London and beyond, including partnerships with the Francis Crick Institute. There are strong industrial links in biotechnology, genomics, and cell therapy, exemplified by successful spin-outs such as Quell Therapeutics.

Future research will build on existing strengths in engineered cell platforms, gene editing, and advanced in vitro models using multicellular organoids. These tools will enable investigations into immune modulation, tissue injury, and liver regeneration.

The integration of machine perfusion technologies with clinical services will support hypothesis-generating discovery science and enable rapid translation into pre-clinical and clinical trials. Across all research streams, there is a strong commitment to collaboration and to developing impactful partnerships with industry.