Join Professor Yanlan Mao of University College London for a research seminar as part of the Force Talk series entitled "Coping with mechanical stress: tissue dynamics during development, homeostasis and repair".

Abstract:

During growth and development, tissue dynamics, such as tissue folding, cell intercalations and oriented cell divisions, are critical for shaping tissues and organs. However, less is known about how tissues regulate their dynamics during tissue homeostasis and repair, to maintain their shape after development. In this talk, we will discuss how mechanical forces can influence each of these processes, such as how differential growth rates can generate precise folds in tissues. We will also discuss how tissues respond to mechanical perturbations, such as stretching or wounding, by altering their mechanical properties via the cytoskeleton and extracellular matrix, to change tissue dynamics, and thus preserve tissue shape and patterning. We combine genetics, advanced imaging, AI-assisted image analysis, experimental biophysics, and computational modelling across multiple animal model systems to study these processes.

Speaker

Yanlan Mao is a Group Leader and Professor of Developmental Biophysics at the Laboratory for Molecular Cell Biology, University College London. 

Mechanics of Life Leverhulme DSP Force Talks Series

Force Talks is a seminar series hosted by the Mechanics of Life Leverhulme Doctoral Scholarship Programme at King's College London. We are honoured to welcome world leaders in mechanobiology.

The series aims to showcase the rapidly expanding interdisciplinary field of mechanobiology and mechanical forces. We welcome those from academia and industry to attend and take part in the discussions.

The programme is funded by the Leverhulme Trust doctoral scholarship grant "Understanding the mechanics of life".

Learn more about the Mechanics of Life Leverhulme Doctoral Scholarship Programme

How to join:

This event will take place online via Microsoft Teams. A link to register for this event to receive a calendar invitation and updates will be availble prior to the talk.

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