Alberto-Sanchez-Fueyo Professor Alberto Sanchez-Fueyo Academics Supervisors Professor of Hepatology Academic Director of the Institute of Liver Studies. Research subject areas Biomedical and life sciences
Cellular uptake and in vivo distribution of mesenchymal-stem-cell-derived extracellular vesicles are protein corona dependent Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression Can regulatory T cells improve outcomes of sensitised patients after HLA-Ab incompatible renal transplantation: study protocol for the Phase IIa GAMECHANgER-1 trial Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote liver allograft tolerance in humans Acute Antibody-mediated rejection in liver transplantation: Impact and applicability of the Banff working group on liver allograft pathology 2016 criteria Biomarkers of Operational Tolerance After Liver Transplantation: Are We There Yet? Exaggerated inflammatory response to bacterial products in decompensated cirrhotic patients is orchestrated by interferons IL-6 and IL-8 IL-2 availability regulates the tissue specific phenotype of murine intra-hepatic Tregs Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote transplantation tolerance in humans Next-generation pathology detection of T cell–antigen-presenting cell immune synapses in human liver allografts Advances in Liver Transplantation: where are we in the pursuit of transplantation tolerance? Efficacy and Safety of Immunosuppression Withdrawal in Pediatric Liver Transplant Recipients: Moving Toward Personalized Management Non-invasive alloimmune risk stratification of long-term liver transplant recipients On the impact of hepatitis C virus and heterologous immunity on alloimmune responses following liver transplantation Preformed T cell alloimmunity and HLA eplet mismatch to guide immunosuppression minimization with tacrolimus monotherapy in kidney transplantation: Results of the CELLIMIN trial The molecular phenotypes of injury, steatohepatitis, and fibrosis in liver transplant biopsies in the INTERLIVER study Banff 2019 Meeting Report: Molecular diagnostics in solid organ transplantation-Consensus for the Banff Human Organ Transplant (B-HOT) gene panel and open source multicenter validation Impact of donor extracellular vesicle release on recipient cell “cross-dressing” following clinical liver and kidney transplantation On minor histocompatibility antigens, mixed chimerism, and transplantation tolerance The molecular diagnosis of rejection in liver transplant biopsies: First results of the INTERLIVER study Understanding, predicting and achieving liver transplant tolerance: from bench to bedside Applicability, Safety And Biological Activity Of Regulatory T Cell Therapy In Liver Transplantation IL-2 therapy preferentially expands adoptively transferred donor-specific Tregs improving skin allograft survival Immune tolerance after liver transplantation Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus Normothermic Machine Perfusion (NMP) Inhibits Proinflammatory Responses in the Liver and Promotes Regeneration PROFIT, a PROspective, randomised placebo controlled feasibility trial of Faecal mIcrobiota Transplantation in cirrhosis: study protocol for a single-blinded trial Biomarkers of immune tolerance in liver transplantation Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants Low Dose Interleukin-2 for Refractory Autoimmune Hepatitis Molecular profiling of subclinical inflammatory lesions in long-term surviving adult liver transplant recipients Multiparametric analysis of circulating exosomes and other small extracellular vesicles by advanced imaging flow cytometry Prevalence of subclinical histological lesions and tolerance biomarkers in long-term adult liver transplant recipients considered for immunosuppression withdrawal Can immunosuppression be stopped after liver transplantation? Conversion to mycophenolate mofetil monotherapy in liver recipients: Calcineurin inhibitor levels are key IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors Immunological Predictors of Nonresponse to Directly Acting Antiviral Therapy in Patients With Chronic Hepatitis C and Decompensated Cirrhosis Immunotherapy in liver transplantation Immunotolerance in Liver Transplantation Regulatory T-cell therapy in liver transplantation Biomarkers and immunopathology of tolerance Hepatic Infiltrates in Operational Tolerant Patients After Liver Transplantation Show Enrichment of Regulatory T Cells Before Proinflammatory Genes Are Downregulated Immune Exhaustion and Transplantation Molecular Characterization of Acute Cellular Rejection Occurring during Intentional Immunosuppression Withdrawal in Liver Transplantation Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients Strategies for minimizing immunosuppression: State of the Art Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation Usefulness of liver stiffness measurement during acute cellular rejection in liver transplantation A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft View all publications
2 September 2024 King's College London and the Foundation for Liver Research announce new institute dedicated to liver studies King’s College London and the Foundation for Liver Research (FLR) are pleased to announce the…