Professor Alberto Sanchez-Fueyo
Professor of Hepatology
- Academic Director of the Institute of Liver Studies
Research interests
- Biomedical and life sciences
Biography
Alberto Sánchez-Fueyo, MD PhD, is Professor of Hepatology, Academic Head of the Institute of Liver Studies at King’s College London, and Honorary Transplant Hepatology Consultant at King’s College Hospital.
His research has focused on understanding the mechanisms of immunological tolerance in transplantation and developing novel immunomodulatory therapies, for which he has received funding from MRC, NIHR, NIH and EU, among others. Additional research interests include the generation of genetically engineered regulatory T cells for immunotherapeutic purposes, which is now being pursued in collaboration with Quell Therapeutics, a King’s spin-off biotech which he contributed to found in 2019.
Cellular uptake and in vivo distribution of mesenchymal-stem-cell-derived extracellular vesicles are protein corona dependent
Liam-Or, R., Faruqu, F. N., Walters, A., Han, S., Xu, L., Wang, J. T. W., Oberlaender, J., Sanchez-Fueyo, A., Lombardi, G., Dazzi, F., Mailaender, V. & Al-Jamal, K. T., Jun 2024, In: Nature Nanotechnology. 19, 6, p. 846-855 10 p.Research output: Contribution to journal › Article › peer-review
Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression
Vionnet, J., Torres-Yaguana, J., Miquel, R., Abraldes, J. G., Wall, J., Kodela, E., Lozano, J.-J., Ruiz, P., Navasa, M., Marshall, A., Nevens, F., Gelson, W., Leithead, J., Masson, S., Jaeckel, E., Taubert, R., Tachtatzis, P., Eurich, D., Simpson, K. J. & Bonaccorsi-Riani, E. & 12 others, Ferguson, J., Quaglia, A., Demetris, A. J., Lesniak, A. J., Elstad, M., Delord, M., Douiri, A., Rebollo-Mesa, I., Martinez-Llordella, M., Silva, J. A. F., Markmann, J. F. & Sánchez-Fueyo, A., 18 Dec 2024, (E-pub ahead of print) In: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.Research output: Contribution to journal › Article › peer-review
Can regulatory T cells improve outcomes of sensitised patients after HLA-Ab incompatible renal transplantation: study protocol for the Phase IIa GAMECHANgER-1 trial
Dudreuilh, C., Jarvis, P., Beadle, N., Pilecka, I., Shaw, O., Gardner, L., Scotta, C., Mamode, N., Game, D., Sanchez Fueyo, A., Lombardi, G., Learoyd, A., Douiri, A. & Dorling, A., 28 Apr 2023, In: BMC Nephrology. 24, 1, 117.Research output: Contribution to journal › Article › peer-review
Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease
Vaikunthanathan, T., Landmann, E., Correa, D. M., Romano, M., Trevelin, S. C., Peng, Q., Crespo, E., Corrado, M., Lozano, J. J., Pearce, E. L., Perpinan, E., Zoccarato, A., Siew, L., Edwards-Hicks, J., Khan, R., Luu, N. T., Thursz, M. R., Newsome, P. N., Martinez-Llordella, M. & Shah, N. & 5 others, Lechler, R. I., Shah, A. M., Sanchez-Fueyo, A., Lombardi, G. & Safinia, N., Sept 2023, In: EBioMedicine. 95, 104778.Research output: Contribution to journal › Article › peer-review
Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote liver allograft tolerance in humans
Lim, T. Y., Perpiñán, E., Londoño, M.-C., Miquel, R., Ruiz, P., Kurt, A. S., Kodela, E., Cross, A. R., Berlin, C., Hester, J., Issa, F., Douiri, A., Volmer, F. H., Taubert, R., Williams, E., Demetris, A. J., Andrew, L., Gilbert, B., Lozano, J. J. & Martinez-llordella, M. & 2 others, Tree, T. & Sánchez-fueyo, A., Jan 2023, In: Journal of Hepatology. 78, 1, p. 153-164 12 p.Research output: Contribution to journal › Article › peer-review
Acute Antibody-mediated rejection in liver transplantation: Impact and applicability of the Banff working group on liver allograft pathology 2016 criteria
Maurice, J. B., Nwaogu, A., Gouda, M., Shaw, O., Sanchez-Fueyo, A. & Zen, Y., Sept 2022, In: Human Pathology. 127, p. 67-77 11 p.Research output: Contribution to journal › Article › peer-review
Biomarkers of Operational Tolerance After Liver Transplantation: Are We There Yet?
Vionnet, J. & Sánchez-Fueyo, A., Jan 2022, In: Liver Transplantation. 28, 1, p. 15-16 2 p.Research output: Contribution to journal › Editorial › peer-review
Exaggerated inflammatory response to bacterial products in decompensated cirrhotic patients is orchestrated by interferons IL-6 and IL-8
Kronsten, V. T., Woodhouse, C. A., Zamalloa, A., Lim, T. Y., Edwards, L. A., Martinez-Llordella, M., Sanchez-Fueyo, A. & Shawcross, D. L., 1 May 2022, In: American journal of physiology. Gastrointestinal and liver physiology. 322, 5, p. G489-G499Research output: Contribution to journal › Article › peer-review
IL-2 availability regulates the tissue specific phenotype of murine intra-hepatic Tregs
Kurt, A. S., Strobl, K., Ruiz, P., Osborn, G., Chester, T., Dawson, L., Warwas, K. M., Grey, E. H., Mastoridis, S., Kodela, E., Safinia, N., Sanchez-Fueyo, A. & Martinez-Llordella, M., 31 Oct 2022, In: Frontiers in Immunology. 13, 1040031.Research output: Contribution to journal › Article › peer-review
Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote transplantation tolerance in humans
Lim, T. Y., Perpinan, E., Carlota Londono, M., Miquel, R., Ruiz, P., Kurt, A., Codela, E., Cross, A., Berlin, C., Hester, J., Issa, F., Douiri, A., Volmer, F., Taubert, R., Williams, E., Demetris, J., Lesniak, A., Bensimon, G., Lozano, J. & Martinez-Llordella, M. & 2 others, Tree, T. & Sanchez-Fueyo, A., Jul 2022, In: Journal of Hepatology. 77, p. S809-S809Research output: Contribution to journal › Meeting Abstract › peer-review
Next-generation pathology detection of T cell–antigen-presenting cell immune synapses in human liver allografts
Wood-Trageser, M. A., Lesniak, D., Gambella, A., Golnoski, K., Feng, S., Bucuvalas, J., Sanchez-Fueyo, A. & Demetris, A. J., 1 Aug 2022, (E-pub ahead of print) In: Hepatology.Research output: Contribution to journal › Article › peer-review
Advances in Liver Transplantation: where are we in the pursuit of transplantation tolerance?
Safinia, N., Vaikunthanathan, T., Lechler, R. I., Sanchez-Fueyo, A. & Lombardi, G., Oct 2021, In: European Journal of Immunology. 51, 10, p. 2373-2386 14 p.Research output: Contribution to journal › Article › peer-review
Efficacy and Safety of Immunosuppression Withdrawal in Pediatric Liver Transplant Recipients: Moving Toward Personalized Management
Feng, S., Bucuvalas, J. C., Mazariegos, G. V., Magee, J. C., Sanchez-Fueyo, A., Spain, K. M., Lesniak, A., Kanaparthi, S., Perito, E., Venkat, V. L., Burrell, B. E., Alonso, E. M., Bridges, N. D., Doo, E., Gupta, N. A., Himes, R. W., Ikle, D., Jackson, A. M., Lobritto, S. J. & Jose Lozano, J. & 8 others, Martinez, M., Ng, V. L., Rand, E. B., Sherker, A. H., Sundaram, S. S., Turmelle, Y. P., Wood-Trageser, M. & Demetris, A. J., May 2021, In: Hepatology. 73, 5, p. 1985-2004 20 p.Research output: Contribution to journal › Article › peer-review
Non-invasive alloimmune risk stratification of long-term liver transplant recipients
Vionnet, J., Miquel, R., Abraldes, J. G., Wall, J., Kodela, E., Lozano, J.-J., Ruiz, P., Navasa, M., Marshall, A., Nevens, F., Gelson, W., Leithead, J., Masson, S., Jaeckel, E., Taubert, R., Tachtatzis, P., Eurich, D., Simpson, K. J., Bonaccorsi-Riani, E. & Feng, S. & 7 others, Bucuvalas, J., Ferguson, J., Quaglia, A., Sidorova, J., Elstad, M., Douiri, A. & Sánchez-Fueyo, A., Dec 2021, In: Journal of Hepatology. 75, 6, p. 1409-1419 11 p.Research output: Contribution to journal › Article › peer-review
On the impact of hepatitis C virus and heterologous immunity on alloimmune responses following liver transplantation
Merritt, E., Londoño, M. C., Childs, K., Whitehouse, G., Kodela, E., Sánchez-Fueyo, A. & Martínez-Llordella, M., Jan 2021, In: American Journal of Transplantation. 21, 1, p. 247-257 11 p.Research output: Contribution to journal › Article › peer-review
Preformed T cell alloimmunity and HLA eplet mismatch to guide immunosuppression minimization with tacrolimus monotherapy in kidney transplantation: Results of the CELLIMIN trial
Bestard, O., Meneghini, M., Crespo, E., Bemelman, F., Koch, M., Volk, H. D., Viklicky, O., Giral, M., Banas, B., Ruiz, J. C., Melilli, E., Hu, L., van Duivenvoorden, R., Nashan, B., Thaiss, F., Otto, N. M., Bold, G., Stein, M., Sefrin, A. & Lachmann, N. & 12 others, Hruba, P., Stranavova, L., Brouard, S., Braudeau, C., Blancho, G., Banas, M., Irure, J., Christakoudi, S., Sanchez-Fueyo, A., Wood, K. J., Reinke, P. & Grinyó, J. M., Aug 2021, In: American Journal of Transplantation. 21, 8, p. 2833-2845 13 p.Research output: Contribution to journal › Article › peer-review
The molecular phenotypes of injury, steatohepatitis, and fibrosis in liver transplant biopsies in the INTERLIVER study
Madill-Thomsen, K. S., Abouljoud, M., Bhati, C., Ciszek, M., Durlik, M., Feng, S., Foroncewicz, B., Francis, I., Grąt, M., Jurczyk, K., Klintmalm, G., Krasnodębski, M., McCaughan, G., Miquel, R., Montano-Loza, A., Moonka, D., Mucha, K., Myślak, M., Pączek, L. & Perkowska-Ptasińska, A. & 8 others, Piecha, G., Reichman, T., Sanchez-Fueyo, A., Tronina, O., Wawrzynowicz-Syczewska, M., Więcek, A., Zieniewicz, K. & Halloran, P. F., 15 Nov 2021, (E-pub ahead of print) In: American Journal of Transplantation.Research output: Contribution to journal › Article › peer-review
Banff 2019 Meeting Report: Molecular diagnostics in solid organ transplantation-Consensus for the Banff Human Organ Transplant (B-HOT) gene panel and open source multicenter validation
Mengel, M., Loupy, A., Haas, M., Roufosse, C., Naesens, M., Akalin, E., Clahsen-van Groningen, M. C., Dagobert, J., Demetris, A. J., Duong van Huyen, J. P., Gueguen, J., Issa, F., Robin, B., Rosales, I., Von der Thüsen, J. H., Sanchez-Fueyo, A., Smith, R. N., Wood, K., Adam, B. & Colvin, R. B., 1 Sept 2020, In: American Journal of Transplantation. 20, 9, p. 2305-2317 13 p.Research output: Contribution to journal › Article › peer-review
Impact of donor extracellular vesicle release on recipient cell “cross-dressing” following clinical liver and kidney transplantation
Mastoridis, S., Londoño, M. C., Kurt, A., Kodela, E., Crespo, E., Mason, J., Bestard, O., Martínez-Llordella, M. & Sánchez-Fueyo, A., 1 Jan 2020, (Accepted/In press) In: American Journal of Transplantation.Research output: Contribution to journal › Article › peer-review
On minor histocompatibility antigens, mixed chimerism, and transplantation tolerance
Sánchez-Fueyo, A. & Dazzi, F., 1 Jan 2020, (Accepted/In press) In: American Journal of Transplantation.Research output: Contribution to journal › Editorial › peer-review
The molecular diagnosis of rejection in liver transplant biopsies: First results of the INTERLIVER study
Madill-Thomsen, K., Abouljoud, M., Bhatti, C., Ciszek, M., Durlik, M., Feng, S., Foroncewicz, B., Francis, I., Grąt, M., Jurczyk, K., Klintmalm, G., Krasnodębski, M., McCaughan, G., Miquel, R., Montano-Loza, A., Moonka, D., Mucha, K., Myślak, M., Pączek, L. & Perkowska-Ptasińska, A. & 8 others, Piecha, G., Reichman, T., Sanchez-Fueyo, A., Tronina, O., Wawrzynowicz-Syczewska, M., Więcek, A., Zieniewicz, K. & Halloran, P. F., 1 Aug 2020, In: American Journal of Transplantation. 20, 8, p. 2156-2172 17 p.Research output: Contribution to journal › Article › peer-review
Understanding, predicting and achieving liver transplant tolerance: from bench to bedside
Thomson, A. W., Vionnet, J. & Sanchez-Fueyo, A., Dec 2020, In: Nature Reviews Gastroenterology and Hepatology. 17, 12, p. 719-739 21 p.Research output: Contribution to journal › Review article › peer-review
Applicability, Safety And Biological Activity Of Regulatory T Cell Therapy In Liver Transplantation
Sánchez-Fueyo, A., Whitehouse, G., Grageda, N., Cramp, M. E., Lim, T. Y., Romano, M., Thirkell, S., Lowe, K., Fry, L., Heward, J., Kerr, A., Ali, J., Fisher, C., Lewis, G., Hope, A., Kodela, E., Lyne, M., Farzaneh, F., Kordasti, S. & Rebollo-Mesa, I. & 5 others, Jose Lozano, J., Safinia, N., Lechler, R., Martínez-Llordella, M. & Lombardi, G., 12 Nov 2019, (E-pub ahead of print) In: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.Research output: Contribution to journal › Article › peer-review
IL-2 therapy preferentially expands adoptively transferred donor-specific Tregs improving skin allograft survival
Ratnasothy, K., Jacob, J., Tung, S. L., Boardman, D. A., Lechler, R. I., Sanchez Fueyo, A., Martinez-Llordella, M. & Lombardi, G., Jul 2019, In: American Journal of Transplantation. 19, 7, p. 2092-2100 9 p.Research output: Contribution to journal › Article › peer-review
Immune tolerance after liver transplantation
Feng, S. & Sanchez-Fueyo, A., 29 Apr 2019, Pediatric Hepatology and Liver Transplantation. Springer International Publishing, p. 625-652 28 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus
Levitsky, J., Burrell, B. E., Kanaparthi, S., Turka, L. A., Kurian, S., Sanchez-Fueyo, A., Lozano, J. J., Demetris, A., Lesniak, A., Kirk, A. D., Stempora, L., Yang, G. Y. & Mathew, J. M., 1 Jan 2019, (Accepted/In press) In: Hepatology.Research output: Contribution to journal › Article › peer-review
Normothermic Machine Perfusion (NMP) Inhibits Proinflammatory Responses in the Liver and Promotes Regeneration
Jassem, W., Xystrakis, E., Ghnewa, Y. G., Yuksel, M., Pop, O., Martinez-Llordella, M., Jabri, Y., Huang, X., Lozano, J. J., Quaglia, A., Sanchez-Fueyo, A., Coussios, C. C., Rela, M., Friend, P., Heaton, N. & Ma, Y., 1 Jan 2019, In: Hepatology. 70, 2, p. 682-695 14 p.Research output: Contribution to journal › Article › peer-review
PROFIT, a PROspective, randomised placebo controlled feasibility trial of Faecal mIcrobiota Transplantation in cirrhosis: study protocol for a single-blinded trial
Woodhouse, C. A., Patel, V. C., Goldenberg, S., Sanchez-Fueyo, A., China, L., O'Brien, A., Flach, C., Douiri, A. & Shawcross, D., 15 Feb 2019, In: BMJ open. 9, 2, p. e023518 e023518.Research output: Contribution to journal › Article › peer-review
Biomarkers of immune tolerance in liver transplantation
Vionnet, J. & Sánchez-Fueyo, A., 17 Feb 2018, (E-pub ahead of print) In: Human Immunology.Research output: Contribution to journal › Article › peer-review
Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants
Feng, S., Bucuvalas, J. C., Demetris, A. J., Burrell, B. E., Spain, K. M., Kanaparthi, S., Magee, J. C., Ikle, D., Lesniak, A., Lozano, J. J., Alonso, E. M., Bray, R. A., Bridges, N. E., Doo, E., Gebel, H. M., Gupta, N. A., Himes, R. W., Jackson, A. M., Lobritto, S. J. & Mazariegos, G. V. & 6 others, Ng, V. L., Rand, E. B., Sherker, A. H., Sundaram, S., Turmelle, Y. P. & Sanchez-Fueyo, A., 23 Aug 2018, (E-pub ahead of print) In: Gastroenterology.Research output: Contribution to journal › Article › peer-review
Low Dose Interleukin-2 for Refractory Autoimmune Hepatitis
Lim, T. Y., Martinez-Llordella, M., Kodela, E., Gray, E., Heneghan, M. A. & Sanchez-Fueyo, A., 5 Oct 2018, In: Hepatology. 68, 4, p. 1649-1652Research output: Contribution to journal › Article › peer-review
Molecular profiling of subclinical inflammatory lesions in long-term surviving adult liver transplant recipients
Londoño, M.-C., Souza, L. N., Lozano, J.-J., Miquel, R., Abraldes, J. G., LLovet, L.-P., Quaglia, A., Rimola, A., Navasa, M. & Sánchez-Fueyo, A., 1 Sept 2018, In: Journal of Hepatology. 69, 3, p. 626-634Research output: Contribution to journal › Article › peer-review
Multiparametric analysis of circulating exosomes and other small extracellular vesicles by advanced imaging flow cytometry
Mastoridis, S., Bertolino, G. M., Whitehouse, G., Dazzi, F., Sanchez-Fueyo, A. & Martinez-Llordella, M., 6 Jul 2018, In: Frontiers in Immunology. 9, JUL, 1583.Research output: Contribution to journal › Article › peer-review
Prevalence of subclinical histological lesions and tolerance biomarkers in long-term adult liver transplant recipients considered for immunosuppression withdrawal
Sanchez-Fueyo, A., Douiri, A., Elstad, M., Kodela, E., Wall, J., Riani, E. B., Alexander, G., Marshall, A., Navasa, M., Ferguson, J., Simpson, K. J., Pascher, A., Jaeckel, E., Tachtatzis, P., Nevens, F. & Masson, S., Apr 2018, In: Journal of Hepatology. 68, p. S27-S27Research output: Contribution to journal › Meeting Abstract › peer-review
Can immunosuppression be stopped after liver transplantation?
Clavien, P.-A., Muller, X., de Oliveira, M. L., Dutkowski, P. & Sanchez-Fueyo, A., Jul 2017, In: The Lancet Gastroenterology & Hepatology. 2, 7Research output: Contribution to journal › Article › peer-review
Conversion to mycophenolate mofetil monotherapy in liver recipients: Calcineurin inhibitor levels are key
Norero, B., Serrano, C. A., Sanchez Fueyo, A., Duarte, I., Torres, J., Ocquetau, M., Barrera, F., Arrese, M., Soza, A. & Benítez, C., 1 Jan 2017, In: Annals Of Hepatology. 16, 1, p. 94-106 13 p.Research output: Contribution to journal › Article › peer-review
IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors
Whitehouse, G., Gray, E., Mastoridis, S., Merritt, E., Kodela, E., Yang, J. H. M., Danger, R., Mairal, M., Christakoudi, S., Lozano, J. J., Macdougall, I. C., Tree, T. I. M., Sanchez-Fueyo, A. & Martinez-Llordella, M., 3 Jul 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 27, p. 7083-7088 6 p.Research output: Contribution to journal › Article › peer-review
Immunological Predictors of Nonresponse to Directly Acting Antiviral Therapy in Patients With Chronic Hepatitis C and Decompensated Cirrhosis
Childs, K., Merritt, E., Considine, A., Sanchez-Fueyo, A., Agarwal, K., Martinez-Llordella, M. & Carey, I., Apr 2017, In: Open Forum Infectious Diseases. 4, 2Research output: Contribution to journal › Article › peer-review
Immunotherapy in liver transplantation
Samuel, D. & Sanchez-Fueyo, A., 23 Aug 2017, (E-pub ahead of print) In: Journal of Hepatology.Research output: Contribution to journal › Article › peer-review
Immunotolerance in Liver Transplantation
Mastoridis, S., Martinez-Llordella, M. & Sanchez-Fueyo, A., 1 May 2017, In: Seminars in Liver Disease. 37, 2, p. 95-108 14 p.Research output: Contribution to journal › Article › peer-review
Regulatory T-cell therapy in liver transplantation
Whitehouse, G. P., Hope, A. & Sanchez-Fueyo, A., 1 Aug 2017, In: Transplant International. 30, 8, p. 776-784 9 p.Research output: Contribution to journal › Review article › peer-review
Biomarkers and immunopathology of tolerance
Mastoridis, S., Martínez-Llordella, M. & Sanchez-Fueyo, A., 2016, In: Current Opinion in Organ Transplantation. 21, 1, p. 81-87 7 p.Research output: Contribution to journal › Article › peer-review
Hepatic Infiltrates in Operational Tolerant Patients After Liver Transplantation Show Enrichment of Regulatory T Cells Before Proinflammatory Genes Are Downregulated
Taubert, R., Danger, R. A. E. D., Londono, M.-C., Christakoudi, S., Martinez-Picola, M., Rimola, A., Manns, M., Sanchez Fueyo, A. & Jaeckel, E., 30 Mar 2016, In: American Journal of Transplantation. 16, 4, p. 1285-1293Research output: Contribution to journal › Article › peer-review
Immune Exhaustion and Transplantation
Sanchez-Fueyo, A. & Markmann, J. F., Jul 2016, In: American Journal of Transplantation. 16, 7, p. 1953-1957 5 p.Research output: Contribution to journal › Article › peer-review
Molecular Characterization of Acute Cellular Rejection Occurring during Intentional Immunosuppression Withdrawal in Liver Transplantation
Bonaccorsi-Riani, E., Pennycuick, A., Londoño, M. C., Lozano, J. J., Benítez, C., Sawitzki, B., Martínez-Picola, M., Bohne, F., Martínez-Llordella, M., Miquel, R., Rimola, A. & Sánchez-Fueyo, A., 28 Feb 2016, In: American Journal of Transplantation. 16, 2, p. 484-496 13 p.Research output: Contribution to journal › Article › peer-review
Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients
Dumontet, E., Danger, R., Vagefi, P. A., Londoño, M. C., Pallier, A., Lozano, J. J., Giral, M., Degauque, N., Soulillou, J. P., Martínez-Llordella, M., Lee, H., Latournerie, M., Boudjema, K., Dulong, J., Tarte, K., Sanchez-Fueyo, A., Feng, S., Brouard, S. & Conchon, S., Mar 2016, In: LIVER INTERNATIONAL. 36, 3, p. 401–409 9 p.Research output: Contribution to journal › Article › peer-review
Strategies for minimizing immunosuppression: State of the Art
Sanchez Fueyo, A., 1 Nov 2016, In: Liver Transplantation. 22, S1, p. 68-70 3 p.Research output: Contribution to journal › Editorial › peer-review
Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation
Safinia, N., Vaikunthanathan, T., Fraser, H., Thirkell, S., Lowe, K., Blackmore, L., Whitehouse, G., Martinez-Llordella, M., Jassem, W., Sanchez-Fueyo, A., Lechler, R. I. & Lombardi, G., 17 Jan 2016, In: Oncotarget. 7, 7, p. 7563-77 15 p.Research output: Contribution to journal › Article › peer-review
Usefulness of liver stiffness measurement during acute cellular rejection in liver transplantation
Crespo, G., Castro-Narro, G., García-Juárez, I., Benítez, C., Ruiz, P., Sastre, L., Colmenero, J., Miquel, R., Sánchez-Fueyo, A., Forns, X. & Navasa, M., Mar 2016, In: Liver Transplantation. 22, 3, p. 298-304 7 p.Research output: Contribution to journal › Article › peer-review
A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft
Baron, D., Ramstein, G., Chesneau, M., Echasseriau, Y., Pallier, A., Paul, C., Degauque, N., Hernandez-Fuentes, M. P., Sanchez-Fueyo, A., Newell, K. A., Giral, M., Soulillou, J.-P., Houlgatte, R. & Brouard, S., 28 Jan 2015, (E-pub ahead of print) In: Kidney International. 87, 5, p. 984-995 12 p.Research output: Contribution to journal › Article › peer-review
Research
Liver immunology and transplantation
A translational research group focused on developing novel immunomodulatory therapies to ameliorate inflammation and induce immunological tolerance in liver diseases and transplantation.
Hepatobiliary neoplasms
King’s College Hospital hosts one of Europe’s largest hepato-pancreato-biliary cancer clinical services.
Mechanistic Evaluation Of Machine Perfusion Strategies In Donation After Circulatory Death Liver Transplantation (iMAPS)
Mechanistic Evaluation Of Machine Perfusion Strategies In Donation After Circulatory Death Liver Transplantation
Project status: Starting
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King's College London and the Foundation for Liver Research announce new institute dedicated to liver studies
King’s College London and the Foundation for Liver Research (FLR) are pleased to announce the establishment of the Roger Williams Institute of Liver Studies...
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Frontiers in Transplantation: Clinical Excellence through Innovation, 2025
Frontiers in Transplantation: Clinical Excellence through Innovation, 2025 will celebrate the links between basic research and medical advances and the impact...
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Cellular uptake and in vivo distribution of mesenchymal-stem-cell-derived extracellular vesicles are protein corona dependent
Liam-Or, R., Faruqu, F. N., Walters, A., Han, S., Xu, L., Wang, J. T. W., Oberlaender, J., Sanchez-Fueyo, A., Lombardi, G., Dazzi, F., Mailaender, V. & Al-Jamal, K. T., Jun 2024, In: Nature Nanotechnology. 19, 6, p. 846-855 10 p.Research output: Contribution to journal › Article › peer-review
Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression
Vionnet, J., Torres-Yaguana, J., Miquel, R., Abraldes, J. G., Wall, J., Kodela, E., Lozano, J.-J., Ruiz, P., Navasa, M., Marshall, A., Nevens, F., Gelson, W., Leithead, J., Masson, S., Jaeckel, E., Taubert, R., Tachtatzis, P., Eurich, D., Simpson, K. J. & Bonaccorsi-Riani, E. & 12 others, Ferguson, J., Quaglia, A., Demetris, A. J., Lesniak, A. J., Elstad, M., Delord, M., Douiri, A., Rebollo-Mesa, I., Martinez-Llordella, M., Silva, J. A. F., Markmann, J. F. & Sánchez-Fueyo, A., 18 Dec 2024, (E-pub ahead of print) In: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.Research output: Contribution to journal › Article › peer-review
Can regulatory T cells improve outcomes of sensitised patients after HLA-Ab incompatible renal transplantation: study protocol for the Phase IIa GAMECHANgER-1 trial
Dudreuilh, C., Jarvis, P., Beadle, N., Pilecka, I., Shaw, O., Gardner, L., Scotta, C., Mamode, N., Game, D., Sanchez Fueyo, A., Lombardi, G., Learoyd, A., Douiri, A. & Dorling, A., 28 Apr 2023, In: BMC Nephrology. 24, 1, 117.Research output: Contribution to journal › Article › peer-review
Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease
Vaikunthanathan, T., Landmann, E., Correa, D. M., Romano, M., Trevelin, S. C., Peng, Q., Crespo, E., Corrado, M., Lozano, J. J., Pearce, E. L., Perpinan, E., Zoccarato, A., Siew, L., Edwards-Hicks, J., Khan, R., Luu, N. T., Thursz, M. R., Newsome, P. N., Martinez-Llordella, M. & Shah, N. & 5 others, Lechler, R. I., Shah, A. M., Sanchez-Fueyo, A., Lombardi, G. & Safinia, N., Sept 2023, In: EBioMedicine. 95, 104778.Research output: Contribution to journal › Article › peer-review
Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote liver allograft tolerance in humans
Lim, T. Y., Perpiñán, E., Londoño, M.-C., Miquel, R., Ruiz, P., Kurt, A. S., Kodela, E., Cross, A. R., Berlin, C., Hester, J., Issa, F., Douiri, A., Volmer, F. H., Taubert, R., Williams, E., Demetris, A. J., Andrew, L., Gilbert, B., Lozano, J. J. & Martinez-llordella, M. & 2 others, Tree, T. & Sánchez-fueyo, A., Jan 2023, In: Journal of Hepatology. 78, 1, p. 153-164 12 p.Research output: Contribution to journal › Article › peer-review
Acute Antibody-mediated rejection in liver transplantation: Impact and applicability of the Banff working group on liver allograft pathology 2016 criteria
Maurice, J. B., Nwaogu, A., Gouda, M., Shaw, O., Sanchez-Fueyo, A. & Zen, Y., Sept 2022, In: Human Pathology. 127, p. 67-77 11 p.Research output: Contribution to journal › Article › peer-review
Biomarkers of Operational Tolerance After Liver Transplantation: Are We There Yet?
Vionnet, J. & Sánchez-Fueyo, A., Jan 2022, In: Liver Transplantation. 28, 1, p. 15-16 2 p.Research output: Contribution to journal › Editorial › peer-review
Exaggerated inflammatory response to bacterial products in decompensated cirrhotic patients is orchestrated by interferons IL-6 and IL-8
Kronsten, V. T., Woodhouse, C. A., Zamalloa, A., Lim, T. Y., Edwards, L. A., Martinez-Llordella, M., Sanchez-Fueyo, A. & Shawcross, D. L., 1 May 2022, In: American journal of physiology. Gastrointestinal and liver physiology. 322, 5, p. G489-G499Research output: Contribution to journal › Article › peer-review
IL-2 availability regulates the tissue specific phenotype of murine intra-hepatic Tregs
Kurt, A. S., Strobl, K., Ruiz, P., Osborn, G., Chester, T., Dawson, L., Warwas, K. M., Grey, E. H., Mastoridis, S., Kodela, E., Safinia, N., Sanchez-Fueyo, A. & Martinez-Llordella, M., 31 Oct 2022, In: Frontiers in Immunology. 13, 1040031.Research output: Contribution to journal › Article › peer-review
Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote transplantation tolerance in humans
Lim, T. Y., Perpinan, E., Carlota Londono, M., Miquel, R., Ruiz, P., Kurt, A., Codela, E., Cross, A., Berlin, C., Hester, J., Issa, F., Douiri, A., Volmer, F., Taubert, R., Williams, E., Demetris, J., Lesniak, A., Bensimon, G., Lozano, J. & Martinez-Llordella, M. & 2 others, Tree, T. & Sanchez-Fueyo, A., Jul 2022, In: Journal of Hepatology. 77, p. S809-S809Research output: Contribution to journal › Meeting Abstract › peer-review
Next-generation pathology detection of T cell–antigen-presenting cell immune synapses in human liver allografts
Wood-Trageser, M. A., Lesniak, D., Gambella, A., Golnoski, K., Feng, S., Bucuvalas, J., Sanchez-Fueyo, A. & Demetris, A. J., 1 Aug 2022, (E-pub ahead of print) In: Hepatology.Research output: Contribution to journal › Article › peer-review
Advances in Liver Transplantation: where are we in the pursuit of transplantation tolerance?
Safinia, N., Vaikunthanathan, T., Lechler, R. I., Sanchez-Fueyo, A. & Lombardi, G., Oct 2021, In: European Journal of Immunology. 51, 10, p. 2373-2386 14 p.Research output: Contribution to journal › Article › peer-review
Efficacy and Safety of Immunosuppression Withdrawal in Pediatric Liver Transplant Recipients: Moving Toward Personalized Management
Feng, S., Bucuvalas, J. C., Mazariegos, G. V., Magee, J. C., Sanchez-Fueyo, A., Spain, K. M., Lesniak, A., Kanaparthi, S., Perito, E., Venkat, V. L., Burrell, B. E., Alonso, E. M., Bridges, N. D., Doo, E., Gupta, N. A., Himes, R. W., Ikle, D., Jackson, A. M., Lobritto, S. J. & Jose Lozano, J. & 8 others, Martinez, M., Ng, V. L., Rand, E. B., Sherker, A. H., Sundaram, S. S., Turmelle, Y. P., Wood-Trageser, M. & Demetris, A. J., May 2021, In: Hepatology. 73, 5, p. 1985-2004 20 p.Research output: Contribution to journal › Article › peer-review
Non-invasive alloimmune risk stratification of long-term liver transplant recipients
Vionnet, J., Miquel, R., Abraldes, J. G., Wall, J., Kodela, E., Lozano, J.-J., Ruiz, P., Navasa, M., Marshall, A., Nevens, F., Gelson, W., Leithead, J., Masson, S., Jaeckel, E., Taubert, R., Tachtatzis, P., Eurich, D., Simpson, K. J., Bonaccorsi-Riani, E. & Feng, S. & 7 others, Bucuvalas, J., Ferguson, J., Quaglia, A., Sidorova, J., Elstad, M., Douiri, A. & Sánchez-Fueyo, A., Dec 2021, In: Journal of Hepatology. 75, 6, p. 1409-1419 11 p.Research output: Contribution to journal › Article › peer-review
On the impact of hepatitis C virus and heterologous immunity on alloimmune responses following liver transplantation
Merritt, E., Londoño, M. C., Childs, K., Whitehouse, G., Kodela, E., Sánchez-Fueyo, A. & Martínez-Llordella, M., Jan 2021, In: American Journal of Transplantation. 21, 1, p. 247-257 11 p.Research output: Contribution to journal › Article › peer-review
Preformed T cell alloimmunity and HLA eplet mismatch to guide immunosuppression minimization with tacrolimus monotherapy in kidney transplantation: Results of the CELLIMIN trial
Bestard, O., Meneghini, M., Crespo, E., Bemelman, F., Koch, M., Volk, H. D., Viklicky, O., Giral, M., Banas, B., Ruiz, J. C., Melilli, E., Hu, L., van Duivenvoorden, R., Nashan, B., Thaiss, F., Otto, N. M., Bold, G., Stein, M., Sefrin, A. & Lachmann, N. & 12 others, Hruba, P., Stranavova, L., Brouard, S., Braudeau, C., Blancho, G., Banas, M., Irure, J., Christakoudi, S., Sanchez-Fueyo, A., Wood, K. J., Reinke, P. & Grinyó, J. M., Aug 2021, In: American Journal of Transplantation. 21, 8, p. 2833-2845 13 p.Research output: Contribution to journal › Article › peer-review
The molecular phenotypes of injury, steatohepatitis, and fibrosis in liver transplant biopsies in the INTERLIVER study
Madill-Thomsen, K. S., Abouljoud, M., Bhati, C., Ciszek, M., Durlik, M., Feng, S., Foroncewicz, B., Francis, I., Grąt, M., Jurczyk, K., Klintmalm, G., Krasnodębski, M., McCaughan, G., Miquel, R., Montano-Loza, A., Moonka, D., Mucha, K., Myślak, M., Pączek, L. & Perkowska-Ptasińska, A. & 8 others, Piecha, G., Reichman, T., Sanchez-Fueyo, A., Tronina, O., Wawrzynowicz-Syczewska, M., Więcek, A., Zieniewicz, K. & Halloran, P. F., 15 Nov 2021, (E-pub ahead of print) In: American Journal of Transplantation.Research output: Contribution to journal › Article › peer-review
Banff 2019 Meeting Report: Molecular diagnostics in solid organ transplantation-Consensus for the Banff Human Organ Transplant (B-HOT) gene panel and open source multicenter validation
Mengel, M., Loupy, A., Haas, M., Roufosse, C., Naesens, M., Akalin, E., Clahsen-van Groningen, M. C., Dagobert, J., Demetris, A. J., Duong van Huyen, J. P., Gueguen, J., Issa, F., Robin, B., Rosales, I., Von der Thüsen, J. H., Sanchez-Fueyo, A., Smith, R. N., Wood, K., Adam, B. & Colvin, R. B., 1 Sept 2020, In: American Journal of Transplantation. 20, 9, p. 2305-2317 13 p.Research output: Contribution to journal › Article › peer-review
Impact of donor extracellular vesicle release on recipient cell “cross-dressing” following clinical liver and kidney transplantation
Mastoridis, S., Londoño, M. C., Kurt, A., Kodela, E., Crespo, E., Mason, J., Bestard, O., Martínez-Llordella, M. & Sánchez-Fueyo, A., 1 Jan 2020, (Accepted/In press) In: American Journal of Transplantation.Research output: Contribution to journal › Article › peer-review
On minor histocompatibility antigens, mixed chimerism, and transplantation tolerance
Sánchez-Fueyo, A. & Dazzi, F., 1 Jan 2020, (Accepted/In press) In: American Journal of Transplantation.Research output: Contribution to journal › Editorial › peer-review
The molecular diagnosis of rejection in liver transplant biopsies: First results of the INTERLIVER study
Madill-Thomsen, K., Abouljoud, M., Bhatti, C., Ciszek, M., Durlik, M., Feng, S., Foroncewicz, B., Francis, I., Grąt, M., Jurczyk, K., Klintmalm, G., Krasnodębski, M., McCaughan, G., Miquel, R., Montano-Loza, A., Moonka, D., Mucha, K., Myślak, M., Pączek, L. & Perkowska-Ptasińska, A. & 8 others, Piecha, G., Reichman, T., Sanchez-Fueyo, A., Tronina, O., Wawrzynowicz-Syczewska, M., Więcek, A., Zieniewicz, K. & Halloran, P. F., 1 Aug 2020, In: American Journal of Transplantation. 20, 8, p. 2156-2172 17 p.Research output: Contribution to journal › Article › peer-review
Understanding, predicting and achieving liver transplant tolerance: from bench to bedside
Thomson, A. W., Vionnet, J. & Sanchez-Fueyo, A., Dec 2020, In: Nature Reviews Gastroenterology and Hepatology. 17, 12, p. 719-739 21 p.Research output: Contribution to journal › Review article › peer-review
Applicability, Safety And Biological Activity Of Regulatory T Cell Therapy In Liver Transplantation
Sánchez-Fueyo, A., Whitehouse, G., Grageda, N., Cramp, M. E., Lim, T. Y., Romano, M., Thirkell, S., Lowe, K., Fry, L., Heward, J., Kerr, A., Ali, J., Fisher, C., Lewis, G., Hope, A., Kodela, E., Lyne, M., Farzaneh, F., Kordasti, S. & Rebollo-Mesa, I. & 5 others, Jose Lozano, J., Safinia, N., Lechler, R., Martínez-Llordella, M. & Lombardi, G., 12 Nov 2019, (E-pub ahead of print) In: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.Research output: Contribution to journal › Article › peer-review
IL-2 therapy preferentially expands adoptively transferred donor-specific Tregs improving skin allograft survival
Ratnasothy, K., Jacob, J., Tung, S. L., Boardman, D. A., Lechler, R. I., Sanchez Fueyo, A., Martinez-Llordella, M. & Lombardi, G., Jul 2019, In: American Journal of Transplantation. 19, 7, p. 2092-2100 9 p.Research output: Contribution to journal › Article › peer-review
Immune tolerance after liver transplantation
Feng, S. & Sanchez-Fueyo, A., 29 Apr 2019, Pediatric Hepatology and Liver Transplantation. Springer International Publishing, p. 625-652 28 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus
Levitsky, J., Burrell, B. E., Kanaparthi, S., Turka, L. A., Kurian, S., Sanchez-Fueyo, A., Lozano, J. J., Demetris, A., Lesniak, A., Kirk, A. D., Stempora, L., Yang, G. Y. & Mathew, J. M., 1 Jan 2019, (Accepted/In press) In: Hepatology.Research output: Contribution to journal › Article › peer-review
Normothermic Machine Perfusion (NMP) Inhibits Proinflammatory Responses in the Liver and Promotes Regeneration
Jassem, W., Xystrakis, E., Ghnewa, Y. G., Yuksel, M., Pop, O., Martinez-Llordella, M., Jabri, Y., Huang, X., Lozano, J. J., Quaglia, A., Sanchez-Fueyo, A., Coussios, C. C., Rela, M., Friend, P., Heaton, N. & Ma, Y., 1 Jan 2019, In: Hepatology. 70, 2, p. 682-695 14 p.Research output: Contribution to journal › Article › peer-review
PROFIT, a PROspective, randomised placebo controlled feasibility trial of Faecal mIcrobiota Transplantation in cirrhosis: study protocol for a single-blinded trial
Woodhouse, C. A., Patel, V. C., Goldenberg, S., Sanchez-Fueyo, A., China, L., O'Brien, A., Flach, C., Douiri, A. & Shawcross, D., 15 Feb 2019, In: BMJ open. 9, 2, p. e023518 e023518.Research output: Contribution to journal › Article › peer-review
Biomarkers of immune tolerance in liver transplantation
Vionnet, J. & Sánchez-Fueyo, A., 17 Feb 2018, (E-pub ahead of print) In: Human Immunology.Research output: Contribution to journal › Article › peer-review
Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants
Feng, S., Bucuvalas, J. C., Demetris, A. J., Burrell, B. E., Spain, K. M., Kanaparthi, S., Magee, J. C., Ikle, D., Lesniak, A., Lozano, J. J., Alonso, E. M., Bray, R. A., Bridges, N. E., Doo, E., Gebel, H. M., Gupta, N. A., Himes, R. W., Jackson, A. M., Lobritto, S. J. & Mazariegos, G. V. & 6 others, Ng, V. L., Rand, E. B., Sherker, A. H., Sundaram, S., Turmelle, Y. P. & Sanchez-Fueyo, A., 23 Aug 2018, (E-pub ahead of print) In: Gastroenterology.Research output: Contribution to journal › Article › peer-review
Low Dose Interleukin-2 for Refractory Autoimmune Hepatitis
Lim, T. Y., Martinez-Llordella, M., Kodela, E., Gray, E., Heneghan, M. A. & Sanchez-Fueyo, A., 5 Oct 2018, In: Hepatology. 68, 4, p. 1649-1652Research output: Contribution to journal › Article › peer-review
Molecular profiling of subclinical inflammatory lesions in long-term surviving adult liver transplant recipients
Londoño, M.-C., Souza, L. N., Lozano, J.-J., Miquel, R., Abraldes, J. G., LLovet, L.-P., Quaglia, A., Rimola, A., Navasa, M. & Sánchez-Fueyo, A., 1 Sept 2018, In: Journal of Hepatology. 69, 3, p. 626-634Research output: Contribution to journal › Article › peer-review
Multiparametric analysis of circulating exosomes and other small extracellular vesicles by advanced imaging flow cytometry
Mastoridis, S., Bertolino, G. M., Whitehouse, G., Dazzi, F., Sanchez-Fueyo, A. & Martinez-Llordella, M., 6 Jul 2018, In: Frontiers in Immunology. 9, JUL, 1583.Research output: Contribution to journal › Article › peer-review
Prevalence of subclinical histological lesions and tolerance biomarkers in long-term adult liver transplant recipients considered for immunosuppression withdrawal
Sanchez-Fueyo, A., Douiri, A., Elstad, M., Kodela, E., Wall, J., Riani, E. B., Alexander, G., Marshall, A., Navasa, M., Ferguson, J., Simpson, K. J., Pascher, A., Jaeckel, E., Tachtatzis, P., Nevens, F. & Masson, S., Apr 2018, In: Journal of Hepatology. 68, p. S27-S27Research output: Contribution to journal › Meeting Abstract › peer-review
Can immunosuppression be stopped after liver transplantation?
Clavien, P.-A., Muller, X., de Oliveira, M. L., Dutkowski, P. & Sanchez-Fueyo, A., Jul 2017, In: The Lancet Gastroenterology & Hepatology. 2, 7Research output: Contribution to journal › Article › peer-review
Conversion to mycophenolate mofetil monotherapy in liver recipients: Calcineurin inhibitor levels are key
Norero, B., Serrano, C. A., Sanchez Fueyo, A., Duarte, I., Torres, J., Ocquetau, M., Barrera, F., Arrese, M., Soza, A. & Benítez, C., 1 Jan 2017, In: Annals Of Hepatology. 16, 1, p. 94-106 13 p.Research output: Contribution to journal › Article › peer-review
IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors
Whitehouse, G., Gray, E., Mastoridis, S., Merritt, E., Kodela, E., Yang, J. H. M., Danger, R., Mairal, M., Christakoudi, S., Lozano, J. J., Macdougall, I. C., Tree, T. I. M., Sanchez-Fueyo, A. & Martinez-Llordella, M., 3 Jul 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 27, p. 7083-7088 6 p.Research output: Contribution to journal › Article › peer-review
Immunological Predictors of Nonresponse to Directly Acting Antiviral Therapy in Patients With Chronic Hepatitis C and Decompensated Cirrhosis
Childs, K., Merritt, E., Considine, A., Sanchez-Fueyo, A., Agarwal, K., Martinez-Llordella, M. & Carey, I., Apr 2017, In: Open Forum Infectious Diseases. 4, 2Research output: Contribution to journal › Article › peer-review
Immunotherapy in liver transplantation
Samuel, D. & Sanchez-Fueyo, A., 23 Aug 2017, (E-pub ahead of print) In: Journal of Hepatology.Research output: Contribution to journal › Article › peer-review
Immunotolerance in Liver Transplantation
Mastoridis, S., Martinez-Llordella, M. & Sanchez-Fueyo, A., 1 May 2017, In: Seminars in Liver Disease. 37, 2, p. 95-108 14 p.Research output: Contribution to journal › Article › peer-review
Regulatory T-cell therapy in liver transplantation
Whitehouse, G. P., Hope, A. & Sanchez-Fueyo, A., 1 Aug 2017, In: Transplant International. 30, 8, p. 776-784 9 p.Research output: Contribution to journal › Review article › peer-review
Biomarkers and immunopathology of tolerance
Mastoridis, S., Martínez-Llordella, M. & Sanchez-Fueyo, A., 2016, In: Current Opinion in Organ Transplantation. 21, 1, p. 81-87 7 p.Research output: Contribution to journal › Article › peer-review
Hepatic Infiltrates in Operational Tolerant Patients After Liver Transplantation Show Enrichment of Regulatory T Cells Before Proinflammatory Genes Are Downregulated
Taubert, R., Danger, R. A. E. D., Londono, M.-C., Christakoudi, S., Martinez-Picola, M., Rimola, A., Manns, M., Sanchez Fueyo, A. & Jaeckel, E., 30 Mar 2016, In: American Journal of Transplantation. 16, 4, p. 1285-1293Research output: Contribution to journal › Article › peer-review
Immune Exhaustion and Transplantation
Sanchez-Fueyo, A. & Markmann, J. F., Jul 2016, In: American Journal of Transplantation. 16, 7, p. 1953-1957 5 p.Research output: Contribution to journal › Article › peer-review
Molecular Characterization of Acute Cellular Rejection Occurring during Intentional Immunosuppression Withdrawal in Liver Transplantation
Bonaccorsi-Riani, E., Pennycuick, A., Londoño, M. C., Lozano, J. J., Benítez, C., Sawitzki, B., Martínez-Picola, M., Bohne, F., Martínez-Llordella, M., Miquel, R., Rimola, A. & Sánchez-Fueyo, A., 28 Feb 2016, In: American Journal of Transplantation. 16, 2, p. 484-496 13 p.Research output: Contribution to journal › Article › peer-review
Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients
Dumontet, E., Danger, R., Vagefi, P. A., Londoño, M. C., Pallier, A., Lozano, J. J., Giral, M., Degauque, N., Soulillou, J. P., Martínez-Llordella, M., Lee, H., Latournerie, M., Boudjema, K., Dulong, J., Tarte, K., Sanchez-Fueyo, A., Feng, S., Brouard, S. & Conchon, S., Mar 2016, In: LIVER INTERNATIONAL. 36, 3, p. 401–409 9 p.Research output: Contribution to journal › Article › peer-review
Strategies for minimizing immunosuppression: State of the Art
Sanchez Fueyo, A., 1 Nov 2016, In: Liver Transplantation. 22, S1, p. 68-70 3 p.Research output: Contribution to journal › Editorial › peer-review
Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation
Safinia, N., Vaikunthanathan, T., Fraser, H., Thirkell, S., Lowe, K., Blackmore, L., Whitehouse, G., Martinez-Llordella, M., Jassem, W., Sanchez-Fueyo, A., Lechler, R. I. & Lombardi, G., 17 Jan 2016, In: Oncotarget. 7, 7, p. 7563-77 15 p.Research output: Contribution to journal › Article › peer-review
Usefulness of liver stiffness measurement during acute cellular rejection in liver transplantation
Crespo, G., Castro-Narro, G., García-Juárez, I., Benítez, C., Ruiz, P., Sastre, L., Colmenero, J., Miquel, R., Sánchez-Fueyo, A., Forns, X. & Navasa, M., Mar 2016, In: Liver Transplantation. 22, 3, p. 298-304 7 p.Research output: Contribution to journal › Article › peer-review
A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft
Baron, D., Ramstein, G., Chesneau, M., Echasseriau, Y., Pallier, A., Paul, C., Degauque, N., Hernandez-Fuentes, M. P., Sanchez-Fueyo, A., Newell, K. A., Giral, M., Soulillou, J.-P., Houlgatte, R. & Brouard, S., 28 Jan 2015, (E-pub ahead of print) In: Kidney International. 87, 5, p. 984-995 12 p.Research output: Contribution to journal › Article › peer-review
Research
Liver immunology and transplantation
A translational research group focused on developing novel immunomodulatory therapies to ameliorate inflammation and induce immunological tolerance in liver diseases and transplantation.
Hepatobiliary neoplasms
King’s College Hospital hosts one of Europe’s largest hepato-pancreato-biliary cancer clinical services.
Mechanistic Evaluation Of Machine Perfusion Strategies In Donation After Circulatory Death Liver Transplantation (iMAPS)
Mechanistic Evaluation Of Machine Perfusion Strategies In Donation After Circulatory Death Liver Transplantation
Project status: Starting
News
King's College London and the Foundation for Liver Research announce new institute dedicated to liver studies
King’s College London and the Foundation for Liver Research (FLR) are pleased to announce the establishment of the Roger Williams Institute of Liver Studies...
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Frontiers in Transplantation: Clinical Excellence through Innovation, 2025
Frontiers in Transplantation: Clinical Excellence through Innovation, 2025 will celebrate the links between basic research and medical advances and the impact...
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