Dr Alfredo Iacoangeli Research fellows Supervisors Research Fellow in Translational Bioinformatics Contact details +44 (0)20 7848 0951 alfredo.iacoangeli@kcl.ac.uk
The impact of age on genetic testing decisions in amyotrophic lateral sclerosis Project MinE ALS Sequencing Consortium, Mehta, P. R., Iacoangeli, A., Opie-Martin, S., van Vugt, J. J. F. A., Al Khleifat, A., Bredin, A., Ossher, L., Andersen, P. M., Hardiman, O., Mehta, A. R., Fratta, P., Talbot, K. & Al-Chalabi, A., 27 Sep 2022, (E-pub ahead of print) In: Brain : a journal of neurology. awac279. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/brain/awac279 RetroSnake: a Modular Pipeline for Detection of Human Endogenous Retroviruses in Genome Sequencing data Kabiljo, R., Bowles, H., Marriott, H., Jones, A. R., Bouton, C. R., Dobson, R. JB., Quinn, J. P., Al Khleifat, A., Swanson, C. M., Al-Chalabi, A. & Iacoangeli, A., 4 Oct 2022, (Accepted/In press) In: iScience. p. 105289 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.isci.2022.105289 Large-scale Analyses of CAV1 and CAV2 Suggest Their Expression is Higher in Post-mortem ALS Brain Tissue and Affects Survival Iacoangeli, A., 6 Feb 2023, (Accepted/In press) In: Frontiers in cellular neuroscience. Research output: Contribution to journal › Article › peer-review An assessment of bioinformatics tools for the detection of human endogenous retroviral insertions in short-read genome sequencing data Iacoangeli, A., 8 Dec 2022, (Accepted/In press) In: Frontiers in Bioinformatics - Computational Bioimaging. Research output: Contribution to journal › Article › peer-review Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data Al Khleifat, A., Iacoangeli, A., Jones, A., van Vugt, J., Shatunov, A., Moisse, M., Shatunov, A., Zwamborn, R. A. J., van der Spek, R., Cooper-Knock, J., Topp, S., van Rheenen, W., Kenna, B. J., van Eijk, K. R., Kenna, K. P., Byrne, R. P., López Alonso, V., Opie-Martin, S., Vural, A., González, Y., & 25 othersWeber, M., Smith, B., Fogh, I., Silani, V., Morrison, K. E., Dobson, R., van Es, M. A., McLaughlin, R. L., Chio, A., Corcia, P., de Carvalho, M., Gotkine, M., Panades, M. P., Mora, J. S., Shaw, P. J., Landers, J. E., Glass, J. D., Shaw, C., Başak, A. N., Hardiman, O., Robberecht, W., Van Damme, P., van den Berg, L., Veldink, J. & Al-Chalabi, A., 15 Nov 2022, In: Frontiers in cellular neuroscience. Research output: Contribution to journal › Article › peer-review RetroSnake: A modular pipeline to detect human endogenous retroviruses in genome sequencing data Kabiljo, R., Bowles, H., Swanson, C., Dobson, R., Al Khleifat, A., Marriott, H., Jones, A., Bouton, C., Quinn, J., Al-Chalabi, A. & Iacoangeli, A., 18 Nov 2022, In: iScience. 25, 11, 105289. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.isci.2022.105289 A polymorphic transcriptional regulatory domain in the amyotrophic lateral sclerosis risk gene CFAP410 correlates with differential isoform expression Marshall, J. N. G., Fröhlich, A., Li, L., Pfaff, A. L., Middlehurst, B., Spargo, T. P., Iacoangeli, A., Lang, B., Al-Chalabi, A., Koks, S., Bubb, V. J. & Quinn, J. P., 5 Sep 2022, In: Frontiers in Molecular Neuroscience. 15, 954928. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3389/fnmol.2022.954928 ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization Project MinE ALS Sequencing Consortium, 2020, In: Brain Communications. 2, 2, fcaa064. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/braincomms/fcaa064 Characterisation of retrotransposon insertion polymorphisms in whole genome sequencing data from individuals with amyotrophic lateral sclerosis Savage, A. L., Iacoangeli, A., Schumann, G. G., Rubio-Roldan, A., Garcia-Perez, J. L., Al Khleifat, A., Koks, S., Bubb, V. J., Al-Chalabi, A. & Quinn, J. P., 15 Nov 2022, In: Gene. 843, 146799. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.gene.2022.146799 Amyotrophic Lateral Sclerosis and Cerebellum Kabiljo, R., Iacoangeli, A., Al-Chalabi, A. & Rosenzweig, I., 15 Jul 2022, (Accepted/In press) In: Scientific Reports. Research output: Contribution to journal › Article › peer-review View all publications
15 March 2023 Dr Alfredo Iacoangeli receives Genes 2022 Young Investigator Award in Human Genomics and Genetic Diseases Dr Alfredo Iacoangeli was recognised by the journal, Genes, for his contributions to the fields of…