Skip to main content
Caroline Vance

Dr Caroline Vance PhD, MSc, MBioch

Senior Lecturer

Research interests

  • Neuroscience


My group investigates the roles of RNA binding proteins in the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), with a focus on the three FET proteins (FUS, EWS, and TAF15). Mutations in FUS cause the most aggressive form of ALS whilst all three FET proteins are found in aggregates in FTD and we study how these contribute to disease using a combination of biochemical techniques and super-resolution microscopy in cell, zebrafish and mouse models. Away from research, I am the Senior Personal Tutor for all PhD students in the Faculty ensuring their well-being during their study. Further, I also participate in education across Neuroscience at King’s with a focus on leading modules on the MSc in Clinical Neuroscience and the BSc in Psychology and Neuroscience.

Please see my Research Staff Profile for more detail

Key collaborators:

  • Dr Jacqueline Mitchell, King's College London
  • Dr Marc-David Ruepp, King’s College London
  • Professor Ludo van den Bosch, University of Leuven