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The Odendall Laboratory studies both sides of host/bacteria interactions, in particular at the level of type I and III interferons. These cytokines are mostly studied for their antiviral properties but we find they have interesting functions in infections with enteric bacterial pathogens like Salmonella and Shigella. In addition, we are interested in identifying and characterising bacterial factors that block or manipulate interferon expression or signalling, and how these actions contribute to pathogenesis.