Professor Chris Frost

Academics

Vice Dean (Research)

Research subject areas

Chemistry

Contact details

Biography

Chris completed his BSc(Hons) and PhD in Organic Synthesis at the University of Loughborough. After a postdoctoral fellowship at the University of Texas at Austin, he joined the Chemistry Department at the University of Bath and in 2011 was promoted to Full Professor in Organic Chemistry.

Chris has run a successful and productive interdisciplinary research programme for over 20 years. His research involves creating new chemical tools for healthcare. Current interdisciplinary projects include developing catalytic processes to modify the structural and physicochemical properties of molecules and biopolymers, post-synthetic modification of oligonucleotides and exploring new concepts and selectivity strategies in protein bioconjugation with organometallic reagents. Chris is one of the academic co-founders of Binx Health a medical diagnostics company that uses patented electrochemical technology to provide a point-of-care platform to test and treat infectious disease. Chris helped establish the Centre for Biosensors, Bioelectronics and Biodevices (C3BIO) at Bath, bringing together research expertise from across the Faculties of Engineering & Design, Science and Health.

Ratiometric electrochemistry: Improving the robustness, reproducibility and reliability of biosensors
Spring, S. A., Goggins, S. & Frost, C. G., 2 Apr 2021, In: Molecules. 26, 8, 2130. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3390/molecules26082130
Pd(II)-Mediated C−H Activation for Cysteine Bioconjugation
Tilden, J. A. R., Lubben, A. T., Reeksting, S. B., Kociok-Köhn, G. & Frost, C. G., 2021, (Accepted/In press) In: Chemistry - A European Journal. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/chem.202104385
An organophosphorus(III)-Selective chemodosimeter for the ratiometric electrochemical detection of phosphines
Spring, S. A., Goggins, S. & Frost, C. G., 1 Jun 2019, In: Chemosensors. 7, 2, 19. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3390/chemosensors7020019
Regioselective Transition-Metal-Catalyzed C-H Functionalization of Anilines
Leitch, J. A. & Frost, C. G., 17 Jul 2018, In: Synthesis (Germany). 50, 14, p. 2693-2706 14 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1055/s-0037-1610142
Ruthenium-catalysed σ-activation for remote: Meta -selective C-H functionalisation
Leitch, J. A. & Frost, C. G., 7 Dec 2017, In: Chemical Society reviews. 46, 23, p. 7145-7153 9 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1039/c7cs00496f
A Highly Regioselective Palladium-Catalyzed O,S Rearrangement of Cyclic Thiocarbonates
Mahy, W., Cabezas-Hayes, S., Kociok-Köhn, G. & Frost, C. G., 24 Nov 2017, In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2017, 43, p. 6441-6444 4 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/ejoc.201701181
Ruthenium-Catalyzed para-Selective C−H Alkylation of Aniline Derivatives
Leitch, J. A., McMullin, C. L., Paterson, A. J., Mahon, M. F., Bhonoah, Y. & Frost, C. G., 20 Nov 2017, In: Angewandte Chemie - International Edition. 56, 47, p. 15131-15135 5 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/anie.201708961
Ratiometric electrochemical detection of Pd•••π interactions: application towards electrochemical molecular logic gates
Goggins, S., Stark, O. P., Naz, C., Marsh, B. J. & Frost, C. G., 3 Oct 2017, In: SUPRAMOLECULAR CHEMISTRY. 29, 10, p. 749-757 9 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1080/10610278.2017.1288910
Beyond C2 and C3: Transition-Metal-Catalyzed C-H Functionalization of Indole
Leitch, J. A., Bhonoah, Y. & Frost, C. G., 1 Sep 2017, In: ACS Catalysis. 7, 9, p. 5618-5627 10 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1021/acscatal.7b01785
Remote C6-Selective Ruthenium-Catalyzed C-H Alkylation of Indole Derivatives via σ-Activation
Leitch, J. A., McMullin, C. L., Mahon, M. F., Bhonoah, Y. & Frost, C. G., 7 Apr 2017, In: ACS Catalysis. 7, 4, p. 2616-2623 8 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1021/acscatal.7b00038

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Professor Chris Frost

Research subject areas

Contact details

Biography

Latest publications

Ratiometric electrochemistry: Improving the robustness, reproducibility and reliability of biosensors

Pd(II)-Mediated C−H Activation for Cysteine Bioconjugation

An organophosphorus(III)-Selective chemodosimeter for the ratiometric electrochemical detection of phosphines

Regioselective Transition-Metal-Catalyzed C-H Functionalization of Anilines

Ruthenium-catalysed σ-activation for remote: Meta -selective C-H functionalisation

A Highly Regioselective Palladium-Catalyzed O,S Rearrangement of Cyclic Thiocarbonates

Ruthenium-Catalyzed para-Selective C−H Alkylation of Aniline Derivatives

Ratiometric electrochemical detection of Pd•••π interactions: application towards electrochemical molecular logic gates

Beyond C2 and C3: Transition-Metal-Catalyzed C-H Functionalization of Indole

Remote C6-Selective Ruthenium-Catalyzed C-H Alkylation of Indole Derivatives via σ-Activation

Professor Chris Frost to join as Vice Dean (Research)

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