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Biography

I lead the Chris Miller lab, where our research aims to better understad the molecular mechanisms that underlie neuronal cell death in neurodegenerative diseases. Our major focus is Alzheimer’s disease and related dementias, and amyotrophic lateral sclerosis (ALS), specifcally in relation to how defects in signal transduction contribute to the neurodegenerative process. We have identified a mechanism that underpins endoplasmic reticulum mitochondrial signaling and showed that it is damaged in some forms of dementia, Parkinson’s disease and ALS, and are currently investigating this further as well as therapeutic routes for correcting this type of neuronal damage.

Please see my Research Staff Profile for more detail

Key publications:

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Key collaborators:

  • Dr Wendy Noble, King's College London
  • Professor Christopher Shaw, King's College London