Dr Luke Roberts Research fellows Research Associate Contact details luke.roberts@kcl.ac.uk +44 (0) 20 7188 3555
Epithelial Coxsackievirus Adenovirus Receptor promotes house dust mite-induced lung inflammation Ortiz-Zapater, E., Llopis Hernandez, V., Bagley, D., Roberts, L., Maguire, T., Voss, F., Mertins, P., Kirchner, M., Peset-Martin, I., Woszczek, G., Rosenblatt, J., Gotthardt, M., Santis, G. & Parsons, M., 27 Oct 2022, In: Nature Communications. 13, 1, 6407. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-022-33882-w Organoids capture tissue-specific innate lymphoid cell development in mice and humans Jowett, G., Read, E., Roberts, L., Coman, D., Vilà González, M., Zabinski, T., Niazi, U., Antunes Dos Reis, R., Trieu, T-J., Danovi, D., Gentleman, E., Vallier, L., Curtis, M., Lord, G. & Neves, J. F., 30 Aug 2022, In: Cell Reports. 40, 9, 111281. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.celrep.2022.111281 Cyclin-dependent kinase 9 as a potential target for anti-TNF resistant inflammatory bowel disease Omer, O. S., Hertweck, A., Roberts, L. B., Lo, J. W., Clough, J. N., Jackson, I., Pantazi, E. D., Irving, P. M., MacDonald, T. T., Pavlidis, P., Jenner, R. G. & Lord, G. M., 2022, In: Cellular and molecular gastroenterology and hepatology. 14, 3, p. 625-641 17 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jcmgh.2022.05.011 Helper-Like Type-1 Innate Lymphoid Cells in Inflammatory Bowel Disease Coman, D., Coales, I., Roberts, L. B. & Neves, J. F., 23 Jun 2022, In: Frontiers in immunology. 13, 903688. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3389/fimmu.2022.903688 Differential regulation of allergic airway inflammation by acetylcholine Roberts, L. B., Berkachy, R., Wayne, M., Patel, D., Schnoeller, C., Lord, G., Gounaris, K., Ryffel, B., Quesniaux, V., Darby, M., Horsnell, W. G. C. & Selkirk, M. E., 3 May 2022, (Accepted/In press) In: Frontiers in immunology. Research output: Contribution to journal › Article › peer-review Heartbreakers or healers? Innate lymphoid cells in cardiovascular disease and obesity. Roberts, L. B., Lord, G. M. & Howard, J. K., 11 May 2022, In: Frontiers in immunology. 13, 903678. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3389/fimmu.2022.903678 A population of naive-like CD4+ T cells stably polarized to the TH1 lineage Lo, J., Vila de Mucha, M., Henderson, S., Roberts, L., Constable, L., Garrido Mesa, N., Hertweck, A., Stolarczyk, E., Houlder, E. L., Jackson, I., MacDonald, A. S., Powell, N., Neves, J. F., Howard, J., Jenner, R. & Lord, G., Apr 2022, In: European Journal of Immunology. 52, 4, p. 566-581 16 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/eji.202149228 Sustained post-developmental T-bet expression is critical for the maintenance of type one innate lymphoid cells in vivo Schroeder, J-H., Roberts, L. B., Meissl, K., Lo, J., Hromadová, D., Hayes, K., Zabinski, T., Read, E., Moreira Heliodoro, C., Antunes Dos Reis, R., Howard, J., Grencis, R., Neves, J. F., Strobl, B. & Lord, G., 29 Oct 2021, In: Frontiers in Immunology. Research output: Contribution to journal › Article › peer-review A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling Goldberg, R., Clough, J. N., Roberts, L. B., Sanchez, J., Kordasti, S., Petrov, N., Hertweck, A., Lorenc, A., Jackson, I., Tasker, S., Appios, A., Omer, O., Parkes, M., Prescott, N., Jenner, R. G., Irving, P. M. & Lord, G. M., 18 Dec 2021, In: Journal of Crohn's & colitis. 15, 12, p. 2054-2065 12 p., jjab103. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/ecco-jcc/jjab103 MicroRNA-142 critically regulates group 2 innate lymphoid cell homeostasis and function. Roberts, L. B., Jowett, G., Read, E., Zabinski, T., Berkachy, R., Selkirk, M. E., Jackson, I., Niazi, U., Anandagoda, N., Araki, M., Araki, K., Kasturiarachchi, J., James, C., Enver, T., Nimmo, R., Antunes Dos Reis, R., Howard, J., Neves, J. F. & Lord, G. M., 1 Jun 2021, In: Journal of Immunology. 206, 11, p. 2725-2739 15 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.4049/jimmunol.2000647 View all publications
30 August 2022 Gut and lung organoids open the door to innate immune cell therapies King’s researchers have found an innovative approach for expanding and maturing innate immune cells…