Professor Eric CW So Academics Professor and Chair in Leukaemia Biology Contact details eric.so@kcl.ac.uk (0) 20 7848 5888
HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia Luo, H., Zhu, G., Eshelman, M. A., Fung, T. K., Lai, Q., Wang, F., Zeisig, B. B., Lesperance, J., Ma, X., Chen, S., Cesari, N., Cogle, C., Chen, B., Xu, B., Yang, F. C., So, C. W. E., Qiu, Y., Xu, M. & Huang, S., 17 Feb 2022, In: MOLECULAR CELL. 82, 4, p. 833-851.e11 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.molcel.2022.01.014 Reconstruction of Human AML Using Functionally and Immunophenotypically Defined Human Haematopoietic Stem and Progenitor Cells as Targeted Populations Zeisig, B. B., Fung, T. K., Troadec, E. & So, C. W. E., 20 Dec 2021, In: Bio-protocol. 11, 24, e4262. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.21769/BioProtoc.4262 KDM5B protein expressed in viable and fertile ΔARID mice exhibit no demethylase activity Jamshidi, S., Catchpole, S., Chen, J., So, C. W. E., Burchell, J., Rahman, M. & Taylor-Papadimitriou, J., 29 Oct 2021, (E-pub ahead of print) In: International Journal of Oncology. 59, 5, 96. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3892/IJO.2021.5276 Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment resistant MLL-rearranged leukemia So, C. W. E., Zeisig, B., Fung, T. K., Zarowiecki, M., Stanojevic, B., Lynn, C. & Mufti, G., 8 Jan 2021, (Accepted/In press) In: Science Translational Medicine. Research output: Contribution to journal › Article Therapeutic Opportunities of Targeting Canonical and Noncanonical PcG/TrxG Functions in Acute Myeloid Leukemia Zeisig, B. B. & So, C. W. E., 2021, In: Annual Review of Genomics and Human Genetics. 22, p. 103-125 23 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1146/annurev-genom-111120-102443 Novel therapeutic strategies for MLL-rearranged leukemias Wong, N. H. M. & So, C. W. E., Sep 2020, In: Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1863, 9, 194584. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1016/j.bbagrm.2020.194584 Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models Romussi, A., Cappa, A., Vianello, P., Brambillasca, S., Cera, M. R., Dal Zuffo, R., Fagà, G., Fattori, R., Moretti, L., Trifirò, P., Villa, M., Vultaggio, S., Cecatiello, V., Pasqualato, S., Dondio, G., So, C. W. E., Minucci, S., Sartori, L., Varasi, M. & Mercurio, C., 14 May 2020, In: Acs Medicinal Chemistry Letters. 11, 5, p. 754-759 6 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1021/acsmedchemlett.9b00604 Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia He, B. L., Yang, N., Man, C. H., Ng, N. K. L., Cher, C. Y., Leung, H. C., Kan, L. L. H., Cheng, B. Y. L., Lam, S. S. Y., Wang, M. L. L., Zhang, C. X., Kwok, H., Cheng, G., Sharma, R., Ma, A. C. H., So, C. W. E., Kwong, Y. L. & Leung, A. Y. H., 7 Apr 2020, In: EMBO Molecular Medicine. 12, 4, e10895. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.15252/emmm.201910895 HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice Luo, H., Zhu, G., Xu, J., Lai, Q., Yan, B., Guo, Y., Fung, T. K., Zeisig, B. B., Cui, Y., Zha, J., Cogle, C., Wang, F., Xu, B., Yang, F. C., Li, W., So, C. W. E., Qiu, Y., Xu, M. & Huang, S., 9 Dec 2019, In: CANCER CELL. 36, 6, p. 645-659.E8 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.ccell.2019.10.011 MLL- AF4, a double-edged sword for iPSC respecification into HSPCs Zeisig, B. B. & Eric So, C. W., 27 Feb 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. 1964-1966 3 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1073/pnas.1800622115 View all publications
26 January 2023 Professor Eric So receives two prestigious international grants for myeloid leukaemia research The Sinergia programme – providing 3 million Swiss francs – is the second prestigious overseas grant…