Biography

My research group studies gene regulation mechanisms underlying the choice between cell proliferation and differentiation. We are especially interested in understanding the roles that RNA processing and noncoding RNAs play in normal development and how defects in these RNA-based mechanisms may contribute to disease.

Please see my Research Staff Profile for more detail

Find out more about my research:

CDN - Eugene Makeyev

Key publications:

• Yap et al. (2018). A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival. Molecular Cell
• (2012). Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention. Genes & Development
• Makeyev et al (2007). The microRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Molecular Cell

Key collaborators:

• Professor Corinne Houart, King's College London
• Professor Andres Ramos, University College London
• Dr Setsuko Sahara, King's College London
• Professor Eric So, King's College London