Professor Francesca Spagnoli Academics Supervisors Professor of Regenerative Medicine Research subject areas Medicine Contact details @LabSpagnoli francesca.spagnoli@kcl.ac.uk
Identification and implication of tissue-enriched ligands in epithelial–endothelial crosstalk during pancreas development Moulis, M., Runser, S. V. M., Glorieux, L., Dauguet, N., Vanderaa, C., Gatto, L., Tyteca, D., Henriet, P., Spagnoli, F. M., Iber, D. & Pierreux, C. E., Dec 2022, In: Scientific Reports. 12, 1, 12498. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-022-16072-y Functional genomics and the future of iPSCs in disease modeling Brooks, I. R., Garrone, C. M., Kerins, C., Kiar, C. S., Syntaka, S., Xu, J. Z., Spagnoli, F. M. & Watt, F. M., 10 May 2022, In: Stem cell reports. 17, 5, p. 1033-1047 15 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1016/j.stemcr.2022.03.019 Development of a 3D atlas of the embryonic pancreas for topological and quantitative analysis of heterologous cell interactions Glorieux, L., Sapala, A., Willnow, D., Moulis, M., Salowka, A., Darrigrand, J. F., Edri, S., Schonblum, A., Sakhneny, L., Schaumann, L., Gómez, H. F., Lang, C., Conrad, L., Guillemot, F., Levenberg, S., Landsman, L., Iber, D., Pierreux, C. E. & Spagnoli, F. M., 1 Feb 2022, In: Development (Cambridge, England). 149, 3, dev199655. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1242/dev.199655 The postnatal pancreatic microenvironment guides β cell maturation through BMP4 production Sakhneny, L., Mueller, L., Schonblum, A., Azaria, S., Burganova, G., Epshtein, A., Isaacson, A., Wilson, H., Spagnoli, F. M. & Landsman, L., 11 Oct 2021, In: Developmental Cell. 56, 19, p. 2703-2711.e5 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.devcel.2021.08.014 Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche Willnow, D., Benary, U., Margineanu, A., Vignola, M. L., Konrath, F., Pongrac, I. M., Karimaddini, Z., Vigilante, A., Wolf, J. & Spagnoli, F. M., 2 Sep 2021, In: Nature. 597, 7874, p. 87-91 5 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41586-021-03844-1 Engineering life in synthetic systems Oriola, D. & Spagnoli, F. M., Jul 2021, In: Development (Cambridge). 148, 14, dev199497. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1242/DEV.199497 Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming Spagnoli, F. & Isaacson, A., Oct 2021, In: Current Opinion in Genetics and Development. 70, p. 32-39 8 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1016/j.gde.2021.05.003 Employing core regulatory circuits to define cell identity Almeida, N., Chung, M. W. H., Drudi, E. M., Engquist, E. N., Hamrud, E., Isaacson, A., Tsang, V. S. K., Watt, F. M. & Spagnoli, F. M., 17 May 2021, In: The EMBO journal. 40, 10, p. e106785 e106785. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.15252/embj.2020106785 The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease Bornstein, S. R., Guan, K., Brunβen, C., Mueller, G., Kamvissi-Lorenz, V., Lechler, R., Trembath, R., Mayr, M., Poston, L., Sancho, R., Ahmed, S., Alfar, E., Aljani, B., Alves, T. C., Amiel, S., Andoniadou, C. L., Bandral, M., Belavgeni, A., Berger, I., Birkenfeld, A. & 74 others, Bonifacio, E., Chavakis, T., Chawla, P., Choudhary, P., Cujba, A. M., Delgadillo Silva, L. F., Demcollari, T., Drotar, D. M., Duin, S., El-Agroudy, N. N., El-Armouche, A., Eugster, A., Gado, M., Gavalas, A., Gelinsky, M., Guirgus, M., Hansen, S., Hanton, E., Hasse, M., Henneicke, H., Heller, C., Hempel, H., Hogstrand, C., Hopkins, D., Jarc, L., Jones, P. M., Kamel, M., Kämmerer, S., King, A. J. F., Kurzbach, A., Lambert, C., Latunde-Dada, Y., Lieberam, I., Liers, J., Li, J. W., Linkermann, A., Locke, S., Ludwig, B., Manea, T., Maremonti, F., Marinicova, Z., McGowan, B. M., Mickunas, M., Mingrone, G., Mohanraj, K., Morawietz, H., Ninov, N., Peakman, M., Persaud, S. J., Pietzsch, J., Cachorro, E., Pullen, T. J., Pyrina, I., Rubino, F., Santambrogio, A., Schepp, F., Schlinkert, P., Scriba, L. D., Siow, R., Solimena, M., Spagnoli, F. M., Speier, S., Stavridou, A., Steenblock, C., Strano, A., Taylor, P., Tiepner, A., Tonnus, W., Tree, T., Watt, F., Werdermann, M., Wilson, M., Yusuf, N. & Ziegler, C. G., 1 Mar 2021, In: Hormone and Metabolic Research. 53, 3, p. 204-206 3 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1055/a-1377-6583 A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation Cozzitorto, C., Mueller, L., Ruzittu, S., Mah, N., Willnow, D., Darrigrand, J. F., Wilson, H., Khosravinia, D., Mahmoud, A. A., Risolino, M., Selleri, L. & Spagnoli, F. M., 26 Oct 2020, In: Developmental Cell. 55, 2, p. 150-162.e6 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.devcel.2020.08.003 View all publications