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King’s People

Professor Gary Cook

Academics
Supervisors

Professor of PET Imaging

Research subject areas

Imaging sciences

Contact details

Biography

Gary Cook trained in radiology and nuclear medicine in London, completing his MD in Quantitative 18F-fluoride PET in Metabolic Bone Diseases at King’s College London. He was appointed to the Chair of Clinical PET Imaging in the School of Biomedical Engineering and Imaging Sciences Cancer Imaging Department and KCL and Guy’s & St Thomas PET Centre and as an honorary consultant physician at Guy’s and St Thomas’ Hospitals in 2011.

Research interests include evaluation of novel SPECT and PET tracers in oncology, multiparametric, multimodality imaging biomarker development and measurement of tumour heterogeneity, multimodality imaging of skeletal metastases and development of oncologic hybrid imaging, including PET/MRI. He is joint clinical lead for the clinical PET service and module lead and examiner for the KCL Nuclear Medicine MSc.

Teaching

Latest publications

Input function and modeling for determining bone metabolic flux using [18F] sodium fluoride PET imaging: A step-by-step guide
Puri, T., Frost, M. L., Moore, A. E. B., Cook, G. J. R. & Blake, G. M., 17 Dec 2022, (E-pub ahead of print) In: Medical physics. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1002/mp.16125
Non-Small Cell Lung Cancer (NSCLC) in Young Adults, Age < 50, Is Associated with Late Stage at Presentation and a Very Poor Prognosis in Patients That Do Not Have a Targeted Therapy Option: A Real-World Study
Hughes, D., Kapiris, M., Podvez Nevajda, A., McGrath, H., Stavraka, C., Ahmad, S., Taylor, B. P., Cook, G., Ghosh, S., Josephs, D., Pintus, E., Gennatas, S., Bille, A., Ryanna, K., Santis, G., Montes, A., Van Hemelrijck, M., Eleni, K., Smith, D., Spicer, J., & 1 othersGeorgiou, A., 9 Dec 2022, In: Cancers. 14, 24, 6056. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3390/cancers14246056
Characteristics and survival of advanced non-small cell lung cancer (NSCLC) in young Black patients: a Guy’s Cancer Centre real-world study.
Hughes, D., Kapiris, M., Podvez Nevajda, A., Stavraka, C., Cook, G., Josephs, D., Ghosh, S., Pintus, E., Gennatas, S., Ahmed, S., Santis, G., Ryanna, K., Montes, A., Smith, D., Karapanagiotou, E., Van Hemelrijck, M., Spicer, J. & Georgiou, A., Oct 2022. Research output: Contribution to conference types › Poster › peer-review
99m Tc-single domain PD-l1 antibody (NM01): a novel imaging biomarker for non-invasive myocardial PD-l1 expression
Nazir, M., Hughes, D., Ting, H. H., Chand, G., Bailey, D., Gibson, V., Adamson, K., Johnson, J., Lyon, A. R. & Cook, G., Sep 2022, In: Heart. 108(suppl_2) Research output: Contribution to journal › Meeting abstract › peer-review. DOIs: https://doi.org/10.1136/heartjnl-2022-BSCI.6
Role of 3'-Deoxy-3'-[18F] Fluorothymidine Positron Emission Tomography-Computed Tomography as a Predictive Biomarker in Argininosuccinate Synthetase 1-Deficient Thoracic Cancers Treated With Pegargiminase
Szyszko, T. A., Dunn, J. T., Phillips, M. M., Bomalaski, J., Sheaff, M. T., Ellis, S., Pike, L., Goh, V., Cook, G. J. R. & Szlosarek, P. W., Sep 2022, In: JTO Clinical and Research Reports. 3, 9, 100382. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jtocrr.2022.100382
18F FDG PET/CT and Novel Molecular Imaging for Directing Immunotherapy in Cancer
Hughes, D. J., Subesinghe, M., Taylor, B., Bille, A., Spicer, J., Papa, S., Goh, V. & Cook, G. J. R., 1 Aug 2022, In: Radiology. 304, 2, p. 246-264 19 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1148/radiol.212481
Eligibility for 177Lu-PSMA therapy depends on the choice of companion diagnostic tracer: a comparison of 68Ga-PSMA-11 and 99mTc-MIP-1404 in metastatic castrate resistant prostate cancer: 68Ga-PSMA-11 & 99mTc-MIP-1404 comparison
Cook, G., Wong, W., Sanghera, B., Mangar, S., Challapalli, A., Bahl, A., Bassett, P., Leaning, D. & Schmidkonz, C., 21 Jul 2022, (Unpublished) In: Journal of Nuclear Medicine. Research output: Contribution to journal › Article › peer-review
Role of 68Ga and 18F PSMA PET/CT and PET/MRI in biochemical recurrence of prostate cancer: a systematic review of prospective studies
Mazrani, W., Cook, G. J. R. & Bomanji, J., 1 Jun 2022, In: Nuclear medicine communications. 43, 6, p. 631-637 7 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1097/MNM.0000000000001557
SPECT/CT using [99mTc]-labeled anti-programmed death-ligand 1 (PD-L1) single-domain antibody (NM-01) to predict response to immune checkpoint inhibition in non-small cell lung cancer: preliminary results from the PD-L1 Expression in Cancer (PECan) study.
Hughes, D., Chand, G., Meszaros, L., Adamson, K., Johnson, J., Bailey, D., Gibson, V., Edmonds, S., Georgiou, A., Karapanagiotou, E., Josephs, D., McLean, E., Ting, H. H., Spicer, J., Goh, V. & Cook, G., 1 Jun 2022, In: Journal of Nuclear Medicine. 63 (supplement 2), 2594. Research output: Contribution to journal › Meeting abstract › peer-review
Radiomic Assessment of Oesophageal Adenocarcinoma. A Critical Review of 18F-FDG PET/CT, PET/MRI and CT
O'Shea, R., Rookyard, C., Withey, S., Cook, G., Tsoka, S. & Goh, V., 28 May 2022, (Accepted/In press) In: Insights into imaging. Research output: Contribution to journal › Article › peer-review

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