Dr Jake Penny is a Postdoctoral Research Associate at King’s College London, working under Professor Melanie Bailey as part of SEISMIC a BBSRC funded national UK research facility dedicated to spatially resolved single cell and sub-cellular omics.

His research centres on developing live cell and sub-cellular lipidomic workflows, leveraging capillary based spatial isolation techniques coupled with downstream LC-MS analysis to profile lipid metabolism at the single cell and sub-cellular level. Within SEISMIC, Jake plays a key role in advancing single cell lipidomics infrastructure, optimising sampling and analytical protocols, and supporting collaborative projects across diverse biological models. 

Jake actively liaises with external research groups to apply SEISMIC’s versatile workflows to studies of lipid dynamics under stress, infection, aging, and mechanical stimulation. Jake’s broader expertise in analytical mass spectrometry spans a range of applications, including the characterisation of canine semiochemicals, investigation of chemical signalling mechanisms in marine invertebrates from complex seawater matrices, and compositional analysis of pulse grains.

Jake’s work reflects a commitment to methodological rigor, interdisciplinary collaboration to further our understanding of the underlying chemical mechanisms of biological processes.