Professor James McDonnell Academics Professor of Molecular Immunology Contact details james.mcdonnell@kcl.ac.uk +44 (0) 02 7848 6970
Interplay between Affinity and Valency in Effector Cell Degranulation: A Model System with Polcalcin Allergens and Human Patient-Derived IgE Antibodies 01 October 2019 Vitamin D (1,25(OH)2D3) induces α-1-antitrypsin synthesis by CD4+ T cells, which is required for 1,25(OH)2D3-driven IL-10 01 May 2019 A mass spectrometry-based modelling workflow for accurate prediction of IgG antibody conformations in the gas phase 21 December 2018 Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody 01 August 2018 Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation 01 January 2018 Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted antiviral functions of APOBEC3G 01 January 2018 Anti-IgE Antibodies 14 December 2017 IgE Trimers Drive SPE-7 Cytokinergic Activity 01 December 2017 Thermal sensitivity and flexibility of the Cε3 domains in immunoglobulin E 24 August 2017 Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab 16 June 2017