Professor James McDonnell Academics Supervisors Professor of Molecular Immunology Research subject areas Immunology Contact details james.mcdonnell@kcl.ac.uk +44 (0) 02 7848 6970
Development of a point‐of‐care test for the detection of MDMA in latent fingerprints using Surface Plasmon Resonance and lateral flow technology Pollard, C., Hudson, M., Mcdonnell, J. M., Royall, P. G. & Wolff, K., Apr 2022, In: Drug Testing And Analysis. 14, 4, p. 613-621 9 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/dta.3196 Reviving lost binding sites: Exploring calcium binding-site transitions between human and murine CD23 Ilkow, V., Davies, A. M., Dhaliwal, B., Beavil, A., Sutton, B. & McDonnell, J., Jul 2021, In: FEBS Open Bio. 11, 7, p. 1827-1840 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/2211-5463.13214 Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation Vester, S. K., Beavil, R. L., Lynham, S., Beavil, A. J., Cunninghame Graham, D. S., McDonnell, J. M. & Vyse, T. J., 1 Jan 2021, In: Journal of Biological Chemistry. 296, 100513. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jbc.2021.100513 Rapid conjugation of antibodies to toxins to select candidates for the development of anti-cancer Antibody-Drug Conjugates (ADCs) Hoffmann, M., Mele, S., Cheung, A., Larcombe-Young, D., Bucaite, G., Sachouli, E., Zlatareva, I., Morad, H., Marlow, R., McDonnell, J., Figini, M., Lacy, K. E., Tutt, A., Spicer, J., Thurston, D., Karagiannis, S. N. & Crescioli, S., 1 Jun 2020, In: Scientific Reports. 10, 1, 22 p., 8869. Research output: Contribution to journal › Article › peer-review Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs) Hoffmann, R. M., Mele, S., Cheung, A., Larcombe-Young, D., Bucaite, G., Sachouli, E., Zlatareva, I., Morad, H. O. J., Marlow, R., McDonnell, J. M., Figini, M., Lacy, K. E., Tutt, A. J. N., Spicer, J. F., Thurston, D. E., Karagiannis, S. N. & Crescioli, S., 1 Jun 2020, In: Scientific Reports. 10, 1, p. 8869 8869. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-020-65860-x NMR backbone assignment of the Cε4 domain of immunoglobulin E Benjamin, S. V., Creeke, P. I., Henry, A. J. & McDonnell, J. M., 1 Apr 2020, In: Biomolecular NMR Assignments. 14, 1, p. 151-155 5 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1007/s12104-020-09936-9 Engineering the Fab fragment of the anti-IgE omalizumab to prevent Fab crystallization and permit IgE-Fc complex crystallization Mitropoulou, A., Ceska, T., Heads, J., Beavil, A., Henry, A. J., McDonnell, J., Sutton, B. & Davies, A. M., 1 Mar 2020, In: Acta Crystallographica Section F:Structural Biology Communications. 76, p. 116-129 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1107/S2053230X20001466 Interplay between Affinity and Valency in Effector Cell Degranulation: A Model System with Polcalcin Allergens and Human Patient–Derived IgE Antibodies Bucaite, G., Kang-Pettinger, T., Moreira, J., Gould, H. J., James, L. K., Sutton, B. & McDonnell, J. M., 1 Oct 2019, In: Journal of Immunology. 203, 7, p. 1693-1700 8 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.4049/jimmunol.1900509 Vitamin D (1,25(OH)2D3) induces α-1-antitrypsin synthesis by CD4+ T cells, which is required for 1,25(OH)2D3-driven IL-10 Dimeloe, S., Rice, L. V., Chen, H., Cheadle, C., Raynes, J., Pfeffer, P., Lavender, P., Richards, D. F., Nyon, M. P., Mcdonnell, J. M., Kemper, C., Gooptu, B. & Hawrylowicz, C. M., May 2019, In: Journal of Steroid Biochemistry and Molecular Biology. 189, p. 1-9 9 p., SBMB_2018_497. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jsbmb.2019.01.014 A mass spectrometry-based modelling workflow for accurate prediction of IgG antibody conformations in the gas phase Hansen, K., Lau, A. M. C., Giles, K., McDonnell, J. M., Struwe, WB., Sutton, B. J. & Politis, A., 21 Dec 2018, In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 57, 52, p. 17194-17199 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/anie.201812018 View all publications