Dr Julia Sarah El-Sayed Moustafa Research fellows Research Fellow Contact details julia.el-sayed_moustafa@kcl.ac.uk
Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19 Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers Age acquired skewed X Chromosome Inactivation is associated with adverse health outcomes in humans Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice Current smoking and COVID-19 risk: results from a population symptom app in over 2.4 million people Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults Symptom clusters in COVID-19: A potential clinical prediction tool from the COVID Symptom Study app Real-time tracking of self-reported symptoms to predict potential COVID-19 X chromosome dosage of histone demethylase KDM5C determines sex differences in adiposity Cell-type heterogeneity in adipose tissue is associated with complex traits and reveals disease-relevant cell-specific eQTLs Epigenetic findings in periodontitis in UK twins: a cross sectional study Fasting and time of day independently modulate circadian rhythm relevant gene expression in adipose and skin tissue Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition Metabolomic Profile of Low Copy-Number Carriers at the Salivary Alpha-Amylase Gene Suggests a Metabolic Shift Towards Lipid-Based Energy Production Multiple rare genetic variants co-segregating with familial IgA nephropathy all act within a single immune-related network Beneficial effect of a high number of copies of salivary amylase AMY1 gene on obesity risk in Mexican children Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity O57 Des variations du nombre de copies au niveau d'un CNV fréquent contribuent très fortement au risque d'obésité famCNV: copy number variant association for quantitative traits in families A new highly penetrant form of obesity due to deletions on chromosome 16p11.2 View all publications
17 August 2020 Molecule in fat tissue could be linked to severe COVID-19, study finds Low levels of a key molecule in fat tissue are linked with health conditions that are risk factors…