Dr Katie Doores Academics Senior Lecturer Contact details katie.doores@kcl.ac.uk +44 (0) 20 7848 9616
Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients Abdul-Jawad, S., Baù, L., Alaguthurai, T., Del Molino Del Barrio, I., Laing, A. G., Hayday, T. S., Monin, L., Muñoz-Ruiz, M., McDonald, L., Francos Quijorna, I., McKenzie, D., Davis, R., Lorenc, A., Chan, J. N. E., Ryan, S., Bugallo-Blanco, E., Yorke, R., Kamdar, S., Fish, M., Zlatareva, I. & 31 others, Vantourout, P., Jennings, A., Gee, S., Doores, K., Bailey, K., Hazell, S., De Naurois, J., Moss, C., Russell, B., Khan, A. A., Rowley, M., Benjamin, R., Enting, D., Alrifai, D., Wu, Y., Zhou, Y., Barber, P., Ng, T., Spicer, J., Van Hemelrijck, M., Kumar, M., Vidler, J., Lwin, Y., Fields, P., Karagiannis, S. N., Coolen, A. C. C., Rigg, A., Papa, S., Hayday, A. C., Patten, P. E. M. & Irshad, S., 5 Jan 2021, In : CANCER CELL. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.ccell.2021.01.001 Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein Rissanen, I., Stass, R., Krumm, S. A., Seow, J., Hulswit, R. J., Paesen, G. C., Hepojoki, J., Vapalahti, O., Lundkvist, Ã…., Reynard, O., Volchkov, V., Doores, K. J., Huiskonen, J. T. & Bowden, T. A., 22 Dec 2020, In : eLife. 9 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.7554/eLife.58242https://doi.org/10.7554/eLife.58242 Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans Seow, J., Graham, C., Merrick, B., Acors, S., Pickering, S., Steel, K. J. A., Hemmings, O., O'Byrne, A., Kouphou, N., Galao, R. P., Betancor, G., Wilson, H. D., Signell, A. W., Winstone, H., Kerridge, C., Huettner, I., Jimenez-Guardeño, J. M., Lista, M. J., Temperton, N., Snell, L. B. & 22 others, Bisnauthsing, K., Moore, A., Green, A., Martinez, L., Stokes, B., Honey, J., Izquierdo-Barras, A., Arbane, G., Patel, A., Tan, M. K. I., O'Connell, L., O'Hara, G., MacMahon, E., Douthwaite, S., Nebbia, G., Batra, R., Martinez-Nunez, R., Shankar-Hari, M., Edgeworth, J. D., Neil, S. J. D., Malim, M. H. & Doores, K. J., 1 Dec 2020, In : Nature Microbiology. 5, 12, p. 1598-1607 10 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41564-020-00813-8 Estimates of the rate of infection and asymptomatic COVID-19 disease in a population sample from SE England Wells, P. M., Doores, K. J., Couvreur, S., Nunez, R. M., Seow, J., Graham, C., Acors, S., Kouphou, N., Neil, S. J. D., Tedder, R. S., Matos, P. M., Poulton, K., Lista, M. J., Dickenson, R. E., Sertkaya, H., Maguire, T. J. A., Scourfield, E. J., Bowyer, R. C. E., Hart, D., O'Byrne, A. & 11 others, Steel, K. J. A., Hemmings, O., Rosadas, C., McClure, M. O., Capedevilla-pujol, J., Wolf, J., Ourselin, S., Brown, M. A., Malim, M. H., Spector, T. & Steves, C. J., Dec 2020, In : Journal of Infection. 81, 6, p. 931-936 6 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1016/j.jinf.2020.10.011 Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection Carter, M. J., Fish, M., Jennings, A., Doores, K. J., Wellman, P., Seow, J., Acors, S., Graham, C., Timms, E., Kenny, J., Neil, S., Malim, M. H., Tibby, S. M. & Shankar-Hari, M., 1 Nov 2020, In : Nature Medicine. 26, 11, p. 1701-1707 7 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41591-020-1054-6 A dynamic COVID-19 immune signature includes associations with poor prognosis Laing, A. G., Lorenc, A., del Molino del Barrio, I., Das, A., Fish, M., Monin, L., Muñoz-Ruiz, M., McKenzie, D. R., Hayday, T. S., Francos-Quijorna, I., Kamdar, S., Joseph, M., Davies, D., Davis, R., Jennings, A., Zlatareva, I., Vantourout, P., Wu, Y., Sofra, V., Cano, F. & 30 others, Greco, M., Theodoridis, E., Freedman, J., Gee, S., Chan, J. N. E., Ryan, S., Bugallo-Blanco, E., Peterson, P., Kisand, K., Haljasmägi, L., Chadli, L., Moingeon, P., Martinez, L., Merrick, B., Bisnauthsing, K., Brooks, K., Ibrahim, M. A. A., Mason, J., Lopez Gomez, F., Babalola, K., Abdul-Jawad, S., Cason, J., Mant, C., Seow, J., Graham, C., Doores, K. J., Di Rosa, F., Edgeworth, J., Shankar-Hari, M. & Hayday, A. C., 1 Oct 2020, In : Nature Medicine. 26, 10, p. 1623-1635 13 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41591-020-1038-6 Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare settings Pickering, S., Betancor, G., Galão, R. P., Merrick, B., Signell, A. W., Wilson, H. D., Kia Ik, M. T., Seow, J., Graham, C., Acors, S., Kouphou, N., Steel, K. J. A., Hemmings, O., Patel, A., Nebbia, G., Douthwaite, S., O'Connell, L., Luptak, J., McCoy, L. E., Brouwer, P. & 11 others, van Gils, M. J., Sanders, R. W., Martinez Nunez, R., Bisnauthsing, K., O'Hara, G., MacMahon, E., Batra, R., Malim, M. H., Neil, S. J. D., Doores, K. J. & Edgeworth, J. D., 24 Sep 2020, In : PLoS Pathogens. 16, 9, p. e1008817 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1371/journal.ppat.1008817 Translational Research in the Time of COVID-19-Dissolving Boundaries Edgeworth, J. D., Batra, R., Nebbia, G., Bisnauthsing, K., MacMahon, E., Sudhanva, M., Douthwaite, S., Goldenberg, S., O'Hara, G., Shankar-Hari, M., Doores, K. J., Martinez-Nunez, R., Hemsley, C., Price, N. M., Lockett, J., Lechler, R. I., Neil, S. J. D. & Malim, M. H., Sep 2020, In : PLoS Pathogens. 16, 9, p. e1008898 e1008898. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1371/journal.ppat.1008898 Real-world evaluation of a novel technology for quantitative simultaneous antibody detection against multiple SARS-CoV-2 antigens in a cohort of patients presenting with COVID-19 syndrome Shaw, A. M., Hyde, C., Merrick, B., James-Pemberton, P., Squires, B. K., Olkhov, R. V., Batra, R., Patel, A., Bisnauthsing, K., Nebbia, G., MacMahon, E., Douthwaite, S., Malim, M., Neil, S., Martinez Nunez, R., Doores, K., Mark, T. K. I., Signell, A. W., Betancor, G., Wilson, H. D. & 3 others, Galão, R. P., Pickering, S. & Edgeworth, J. D., 21 Aug 2020, In : Analyst. 145, 16, p. 5638-5646 9 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1039/d0an01066a A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex Avanzato, V. A., Oguntuyo, K. Y., Escalera-Zamudio, M., Gutierrez, B., Golden, M., Kosakovsky Pond, S. L., Pryce, R., Walter, T. S., Seow, J., Doores, K. J., Pybus, O. G., Munster, V. J., Lee, B. & Bowden, T. A., 10 Dec 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 50, p. 25057-25067 11 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1073/pnas.1912503116 View all publications
13 July 2020 Covid-19 antibodies can decline over time, research suggests Antibody responses to SARS-CoV-2 can peak three weeks post onset of symptoms but begin to decline…