Professor Katie Doores Academics Supervisors Professor of Viral Immunology School Academic Lead, Postgraduate Research. Research subject areas Immunology Contact details katie.doores@kcl.ac.uk +44 (0) 20 7848 9616
Geographical Differences in SARS-CoV-2 Antibody Response Dynamics and Neutralisation Profiles to Mild COVID-19: Lessons from a UK–Uganda Comparison Glycan recognition by collectin-11 drives SARS-CoV-2 infectivity and membrane injury of respiratory epithelial cells Long-Term Immune Consequences of Initial SARS-CoV-2 A.23.1 Exposure: A Longitudinal Study of Antibody Responses and Cross-Neutralization in a Ugandan Cohort A monoclonal antibody targeting the Nipah virus fusion glycoprotein apex imparts protection from disease Antibodies to the RBD of SARS-CoV-2 spike mediate productive infection of primary human macrophages Courage in decision-making: A mixed-methods study of COVID-19 vaccine uptake in women of reproductive age in the UK Profiling serum immunodominance following SARS-CoV-2 primary and breakthrough infection reveals distinct variant-specific epitope usage and immune imprinting Antibody levels following vaccination against SARSCoV-2: associations with post-vaccination infection and risk factors in two UK longitudinal studies Broad and potent neutralizing antibodies are elicited in vaccinated individuals following Delta/BA.1 breakthrough infection Endogenous antibody responses in REGN-COV2 treated SARS-CoV-2 infected individuals Humoral immunity to phlebovirus infection Long-COVID fatigue is not predicted by pre-pandemic plasma IL-6 levels in mild COVID-19 Metabolomic and gut microbiome profiles across the spectrum of community-based COVID and non-COVID disease Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein The effects of COVID-19 on cognitive performance in a community-based cohort: a COVID symptom study biobank prospective cohort study Trends in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and vaccine antibody prevalence in a multi-ethnic inner-city antenatal population: A cross-sectional surveillance study VelcroVax: a “Bolt-On” Vaccine Platform for Glycoprotein Display ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19 A neutralizing epitope on the SD1 domain of SARS-CoV-2 Spike targeted following infection and vaccination. BNT162b2 COVID-19 and ChAdOx1 nCoV-19 vaccination in patients with myelodysplastic syndromes Boosting of Waned Humoral and Cellular Responses to SARS-CoV-2 Variants of Concern Among Patients with Cancer Boosting of Waned Humoral and Cellular Responses to SARS-CoV-2 Variants of Concern Among Patients with Cancer Broad Neutralization of SARS-CoV-2 Variants, Including Omicron, following Breakthrough Infection with Delta in COVID-19-Vaccinated Individuals ChAdOx1 nCoV-19 vaccine elicits monoclonal antibodies with cross-neutralizing activity against SARS-CoV-2 viral variants Combined epidemiological and genomic analysis of nosocomial SARS-CoV-2 infection early in the pandemic and the role of unidentified cases in transmission Concordance of B- and T-cell responses to SARS-CoV-2 infection, irrespective of symptoms suggestive of COVID-19 Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies Cross-reactivity of glycan-reactive HIV-1 broadly neutralizing antibodies with parasite glycans Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD™ vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike Global patterns of antigen receptor repertoire disruption across adaptive immune compartments in COVID-19 Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a longitudinal cohort study Impaired humoral and T cell response to vaccination against SARS-CoV-2 in chronic myeloproliferative neoplasm patients treated with ruxolitinib Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records Modular capsid decoration boosts adenovirus vaccine-induced humoral immunity against SARS-CoV-2 SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies SARS-CoV-2-Specific Memory B Cell Responses Are Maintained After Recovery from Natural Infection and Postvaccination SARS-CoV-2–specific memory B cells can persist in the elderly who have lost detectable neutralizing antibodies The effect of Omicron breakthrough infection and extended BNT162b2 booster dosing on neutralization breadth against SARS-CoV-2 variants of concern Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients Broadly neutralizing antibody responses in the longitudinal primary HIV-1 infection Short Pulse Anti-Retroviral Therapy at Seroconversion cohort Clinical utility of targeted SARS-CoV-2 serology testing to aid the diagnosis and management of suspected missed, late or post-COVID-19 infection syndromes: Results from a pilot service implemented during the first pandemic wave Comparative performance of SARS-CoV-2 lateral flow antigen tests and association with detection of infectious virus in clinical specimens: a laboratory evaluation study Erratum: Repeated vaccination against SARS-CoV-2 elicits robust polyfunctional T cell response in allogeneic stem cell transplantation recipients (Cancer Cell (2021) 39(11) (1448–1449), (S1535610821005444), (10.1016/j.ccell.2021.10.002)) Humoral and cellular immunity to delayed second dose of SARS-CoV-2 BNT162b2 mRNA vaccination in patients with cancer Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant Repeated vaccination against SARS-CoV-2 elicits robust polyfunctional T cell response in allogeneic stem cell transplantation recipients Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study View all publications
18 January 2023 Dr Katie Doores receives esteemed Blavatnik Award for Young Scientists Katie is one of three Blavatnik Laureates, winning the Life Sciences category for her research which…