Dr Katie Doores Academics Supervisors Senior Lecturer School Academic Lead, Postgraduate Research. Research subject areas Chemistry Contact details katie.doores@kcl.ac.uk +44 (0) 20 7848 9616
Concordance of B- and T-cell responses to SARS-CoV-2 infection, irrespective of symptoms suggestive of COVID-19 Österdahl, M. F., Christakou, E., Hart, D., Harris, F., Shahrabi, Y., Pollock, E., Wadud, M., Spector, T. D., Brown, M. A., Seow, J., Malim, M. H., Steves, C. J., Doores, K. J., Duncan, E. L. & Tree, T., Nov 2022, In: Journal of Medical Virology. 94, 11, p. 5217-5224 8 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/jmv.28016 Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike Cantoni, D., Murray, M. J., Kalemera, M. D., Dicken, S. J., Stejskal, L., Brown, G., Lytras, S., Coey, J. D., McKenna, J., Bridgett, S., Simpson, D., Fairley, D., Thorne, L. G., Reuschl, A. K., Forrest, C., Ganeshalingham, M., Muir, L., Palor, M., Jarvis, L., Willett, B., & 10 othersPower, U. F., McCoy, L. E., Jolly, C., Towers, G. J., Doores, K. J., Robertson, D. L., Shepherd, A. J., Reeves, M. B., Bamford, C. G. G. & Grove, J., 6 Oct 2022, In: EMBO Reports. 23, 10, e54322. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.15252/embr.202154322 Global patterns of antigen receptor repertoire disruption across adaptive immune compartments in COVID-19 Joseph, M., Wu, Y., Dannebaum, R., Rubelt, F., Zlatareva, I., Lorenc, A., Du, Z. G., Davies, D., Kyle-Cezar, F., Das, A., Gee, S., Seow, J., Graham, C., Telman, D., Bermejo, C., Lin, H., Asgharian, H., Laing, A. G., Del Molino Del Barrio, I., Monin, L., & 21 othersMuñoz-Ruiz, M., McKenzie, D. R., Hayday, T. S., Francos-Quijorna, I., Kamdar, S., Davis, R., Sofra, V., Cano, F., Theodoridis, E., Martinez, L., Merrick, B., Bisnauthsing, K., Brooks, K., Edgeworth, J., Cason, J., Mant, C., Doores, K. J., Vantourout, P., Luong, K., Berka, J. & Hayday, A. C., 23 Aug 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 34, p. e2201541119 e2201541119. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1073/pnas.2201541119 SARS-CoV-2-Specific Memory B Cell Responses Are Maintained After Recovery from Natural Infection and Postvaccination Moore, T., Hossain, R., Doores, K. J., Shankar-Hari, M. & Fear, D. J., 2 Aug 2022, In: Viral Immunology. 35, 6, p. 425-436 12 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1089/vim.2022.0013 ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19 El-Sayed Moustafa, J. S., Jackson, A. U., Brotman, S. M., Guan, L., Villicaña, S., Roberts, A. L., Zito, A., Bonnycastle, L., Erdos, M. R., Narisu, N., Stringham, H. M., Welch, R., Yan, T., Lakka, T., Parker, S., Tuomilehto, J., Seow, J., Graham, C., Huettner, I., Acors, S., & 16 othersKouphou, N., Wadge, S., Duncan, E. L., Steves, C. J., Doores, K. J., Malim, M. H., Collins, F. S., Pajukanta, P., Boehnke, M., Koistinen, H. A., Laakso, M., Falchi, M., Bell, J. T., Scott, L. J., Mohlke, K. L. & Small, K. S., Aug 2022, In: International Journal of Obesity. 46, 8, p. 1478-1486 9 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41366-022-01136-w A neutralizing epitope on the SD1 domain of SARS-CoV-2 Spike targeted following infection and vaccination. Seow, J., Khan, H., Rosa, A., Calvaresi, V., Graham, C., Pickering, S., Pye, V. E., Cronin, N., Huettner, I., Malim, M., Politis, A., Cherepanov, P. & Doores, K., 26 Jul 2022, (Accepted/In press) In: Cell Reports. Research output: Contribution to journal › Article › peer-review Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records Thompson, E. J., Williams, D. M., Walker, A. J., Mitchell, R. E., Niedzwiedz, C. L., Yang, T. C., Huggins, C. F., Kwong, A. S. F., Silverwood, R. J., Di Gessa, G., Bowyer, R., Northstone, K., Hou, B., Green, M. J., Dodgeon, B., Doores, K., Duncan, E., Williams, F., Steptoe, A., Porteous, D. J., & 11 othersMcEachan, R. R. C., Tomlinson, L., Goldacre, B., Patalay, P., Ploubidis, G. B., Katikireddi, S. V., Tilling, K., Rentsch, C. T., Timpson, N. J., Chaturvedi, N. & Steves, C., 28 Jun 2022, In: Nature Communications. 13, 1, p. 3528 1 p., 3528. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-022-30836-0 ChAdOx1 nCoV-19 vaccine elicits monoclonal antibodies with cross-neutralizing activity against SARS-CoV-2 viral variants Seow, J., Graham, C., Hallett, S., Lechmere, T., Maguire, T., Huettner, I., Cox, D., Khan, H., Pickering, S., Waters, A., Ward, C., Mant, C., Pitcher, M., Spencer, J., Fox, J., Malim, M. & Doores, K., 3 May 2022, In: Cell Reports. 39, 5, 110757. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.celrep.2022.110757 BNT162b2 COVID-19 and ChAdOx1 nCoV-19 vaccination in patients with myelodysplastic syndromes Abdul-Jawad, S., Beatson, R., Lechmere, T., Graham, R., Alaguthurai, T., Graham, C., Vidler, J., Kulasekararaj, A., Patten, P. E., Doores, K. J. & Irshad, S., May 2022, In: Haematologica. 107, 5, p. 1181-1184 4 p. Research output: Contribution to journal › Letter › peer-review. DOIs: https://doi.org/10.3324/haematol.2021.280337 SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies Fielding, C. A., Sabberwal, P., Williamson, J. C., Greenwood, E. J. D., Crozier, T. W. M., Zelek, W., Seow, J., Graham, C., Huettner, I., Edgeworth, J. D., Price, D., Morgan, B. P., Ladell, K., Eberl, M., Humphreys, I. R., Merrick, B., Doores, K., Wilson, S. J., Lehner, P. J., Wang, E. C. Y., & 1 othersStanton, R. J., May 2022, In: eLife. 11, e74489. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.7554/eLife.74489 View all publications
21 October 2022 King's study provides vital information to guide COVID-19 vaccine development The researchers examined antibodies from people who had recovered from COVID-19 in multiple…