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Kourosh  Ebrahimi

Dr Kourosh Ebrahimi

Lecturer in Immunology and Drug Discovery

Contact details

Biography

After finishing his M.Sc. studies in Biochemical Engineering (Department of Chemical Engineering, TU Delft), Kourosh did his PhD studies with Professor Wilfred R. Hagen (Department of Biotechnology, TU Delft). He studied the mechanism of iron-storage by the ubiquitous protein ferritin. Subsequently, he did two postdocs with Professor Michael Farzan (the Scripps Research Institute, USA) and Professor (Wilfred R. Hagen, TU Delft). In November 2015, he joined the group of Professor Fraser A. Armstrong (Department of Chemistry, University of Oxford) as a fellow of the European Molecular Biology Organization (EMBO). He established a new research program in bioinorganic immunology and virology, elucidating the function of iron-sulphur proteins in the immune response and viral infection. Kourosh Joined the Institute of Pharmaceutical Sciences at KCL in November 2021. Here, his research objectives are understanding the role of bioinorganic cofactors like iron-sulphur clusters in the immune response and viral infection and discovering new therapeutic candidates for human diseases like viral infection and cancer.

His group applies a combination of molecular and cellular biology, spectroscopic techniques and high-resolution mass spectrometry in three complementary research areas:

  • Discovery and chemoenzymatic synthesis of natural-product based antiviral or antimicrobial lead molecules
  • Engineering protein nanocages to develop novel therapeutics and prophylactics
  • Elucidating the role of metals and bioinorganic cofactors like iron-sulphur clusters in the innate immune response and viral infection

His group collaborates with several leading research groups at King’s College London and other institutes in the UK and Europe. 

The Kourosh Lab web page can be viewed here.

    Research

    Untitled design (9)
    Drug Discovery

    The Drug Discovery Group brings together scientific expertise in a broad range of areas, from medicinal chemistry to systems biology and pharmacology.

    AMR thumbnail
    Antimicrobial Research Theme

    Antimicrobial Research Theme

    News

    Technique opens up potential for producing new antivirals

    King’s researchers have developed a new technique that allows them to identify novel, naturally occurring antiviral molecules that could be used to help...

    lcms vitas assay pic 780x450

    Researchers suggest that [FeS] clusters act as biological fuses in many proteins involved in the immune response

    A team of researchers led by Dr Kourosh Ebrahimi from the School of Cancer & Pharmaceutical Sciences, investigate the role of iron-sulphur ([FeS]) clusters...

    kourosh ebrahimi painting

    Features

    5 minutes with... Kourosh Ebrahimi

    Kourosh Ebrahimi is a Lecturer in Immunology and Drug Discovery in the School of Cancer & Pharmaceutical Sciences. We took 5 minutes with him to ask about his...

    Untitled design (56)

      Research

      Untitled design (9)
      Drug Discovery

      The Drug Discovery Group brings together scientific expertise in a broad range of areas, from medicinal chemistry to systems biology and pharmacology.

      AMR thumbnail
      Antimicrobial Research Theme

      Antimicrobial Research Theme

      News

      Technique opens up potential for producing new antivirals

      King’s researchers have developed a new technique that allows them to identify novel, naturally occurring antiviral molecules that could be used to help...

      lcms vitas assay pic 780x450

      Researchers suggest that [FeS] clusters act as biological fuses in many proteins involved in the immune response

      A team of researchers led by Dr Kourosh Ebrahimi from the School of Cancer & Pharmaceutical Sciences, investigate the role of iron-sulphur ([FeS]) clusters...

      kourosh ebrahimi painting

      Features

      5 minutes with... Kourosh Ebrahimi

      Kourosh Ebrahimi is a Lecturer in Immunology and Drug Discovery in the School of Cancer & Pharmaceutical Sciences. We took 5 minutes with him to ask about his...

      Untitled design (56)