Mark Richardson is Paul Getty III Professor of Epilepsy and Head of School of Neuroscience at the Institute of Psychiatry, Psychology & Neuroscience at King's College London. 

Mark's 'ab studies individuals with epilepsy, focusing on one broad question: why do epileptic seizures start?

In collaboration with mathematicians and engineers, we construct models of the human brain using a range of imaging and neurophysiological techniques, such as functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), electroencephalography (EEG), simultaneous EEG-fMRI and simultaneous transcranial magnetic stimulation (TMS)-EEG.

He aims to understand the underlying mechanisms of seizure onset in terms of such models, comparing healthy people with people who have epilepsy. We also examine how antiepileptic drugs alter brain networks.

In addition, his labs is investigating the long-timescale mechanisms of epilepsy, through long-term monitoring of physiological parameters in people with epilepsy, using wearable and implantable sensors. They will use these data to understand why seizures occur at particular times and to forecast seizure onset in real time.

Find out more about my research

• Richardson Lab

Key Publications

• Tangwiriyasakul et al., 2018. Dynamic brain network states in human generalised spike-wave discharges. Brain. 
• Kuhlmann et al., 2018. Seizure prediction: ready for a new era. Nature Reviews Neurology.
• Terry et al., 2012. Seizure generation: The role of nodes and networks. Epilepsia.

Key Collaborators

• Dr Marc Goodfellow, University of Exeter
• Professor Dr Andreas Schulze-Bonhage, University of Freibrug
• Dr Ben Brinkmann, Mayo Clinic, Rochester
• Dr Dean Freestone, Seer Medical, Melbourne