Professor Martin Ulmschneider Professor Martin Ulmschneider Academics Supervisors Head of Department of Chemistry Professor of Computational Chemistry. Computing Lead. Research subject areas Chemistry Contact details martin.ulmschneider@kcl.ac.uk +44 (0)20 7848 7075
Integrated Design of a Membrane-Lytic Peptide-Based Intravenous Nanotherapeutic Suppresses Triple-Negative Breast Cancer Chen, C. H., Liu, Y. H., Eskandari, A., Ghimire, J., Lin, L. C. W., Fang, Z. S., Wimley, W. C., Ulmschneider, J. P., Suntharalingam, K., Hu, C. M. J. & Ulmschneider, M. B., 5 May 2022, In: Advanced Science. 9, 13, 2105506. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1002/advs.202105506 Atomistic Model of Solute Transport across the Blood-Brain Barrier Jorgensen, C., Ulmschneider, M. B. & Searson, P. C., 11 Jan 2022, In: ACS Omega. 7, 1, p. 1100-1112 13 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1021/acsomega.1c05679 Predicting Membrane-Active Peptide Dynamics in Fluidic Lipid Membranes Chen, C. H., Pepper, K., Ulmschneider, J. P., Ulmschneider, M. B. & Lu, T. K., 2022, Methods in Molecular Biology. Humana Press Inc, p. 115-136 22 p. (Methods in Molecular Biology; vol. 2405). Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review. DOIs: https://doi.org/10.1007/978-1-0716-1855-4_6 Tuning of a Membrane-Perforating Antimicrobial Peptide to Selectively Target Membranes of Different Lipid Composition Chen, C. H., Starr, C. G., Guha, S., Wimley, W. C., Ulmschneider, M. B. & Ulmschneider, J. P., Feb 2021, In: Journal of Membrane Biology. 254, 1, p. 75-96 22 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1007/s00232-021-00174-1 Understanding and modelling the interactions of peptides with membranes: from partitioning to self-assembly Chen, C. H., Melo, M. CR., Berglund, N., Khan, A., de la Fuente, C., Ulmschneider, J. P. & Ulmschneider, M. B., 1 Apr 2020, In: Current Opinion in Structural Biology. 61, p. 160-166 7 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1016/j.sbi.2019.12.021 Mechanisms of a Small Membrane-Active Antimicrobial Peptide from Hyla punctata Chen, C. H., Ulmschneider, J. P. & Ulmschneider, M. B., Mar 2020, In: AUSTRALIAN JOURNAL OF CHEMISTRY. 73, 3, p. 236-245 10 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1071/CH19429 Passive Internalization of Bioactive β-Casein Peptides into Phospholipid (POPC) Bilayers. Free Energy Landscapes from Unbiased Equilibrium MD Simulations at μs-Time Scale Jardón-Valadez, E., Chen, C. H., García-Garibay, M., Jiménez-Guzmán, J. & Ulmschneider, M. B., 1 Jan 2020, (Accepted/In press) In: Food Biophysics. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1007/s11483-020-09651-x An experimentally validated approach to calculate the blood-brain barrier permeability of small molecules Wang, Y., Gallagher, E., Jorgensen, C., Troendle, E. P., Hu, D., Searson, P. C. & Ulmschneider, M. B., 1 Dec 2019, In: Scientific Reports. 9, 1, 6117. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-019-42272-0 Simulation-Guided Rational de Novo Design of a Small Pore-Forming Antimicrobial Peptide Chen, C. H., Starr, C. G., Troendle, E., Wiedman, G., Wimley, W. C., Ulmschneider, J. P. & Ulmschneider, M. B., 27 Mar 2019, In: Journal of the American Chemical Society. 141, 12, p. 4839-4848 10 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1021/jacs.8b11939 Predicting drug delivery efficiency into tumor tissues through molecular simulation of transport in complex vascular networks Troendle, E. P., Khan, A., Searson, P. C. & Ulmschneider, M. B., 8 Nov 2018, (E-pub ahead of print) In: JOURNAL OF CONTROLLED RELEASE. 292, p. 221-234 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.jconrel.2018.11.010 View all publications
27 July 2022 Drug treatment for triple negative breast cancer King's research into breast cancer treatment moves to in-licensing