Professor Matthew Hotopf CBE Academics Supervisors Executive Dean, Institute of Psychiatry, Psychology & Neuroscience Better Health & Care Future Co-director. Research subject areas Neuroscience Psychiatry Psychology Contact details matthew.hotopf@kcl.ac.uk
Multilingual Lexical Feature Analysis of Spoken Language for Predicting Major Depression Symptom Severity Exploring biases related to the use of large language models in a multilingual depression corpus Internalising Problems and Self-reported BMI/Physical Health: Correlated Genetic and Environmental Influences Versus Probable Causal Mechanisms Investigating mechanisms & monitoring outcomes in functional neurological disorder: The unrealised potential of digital remote monitoring technologies Unlocking Mental Health Insights with UK Biobank Data: Past Use and Future Opportunities Does the ethnicity distribution of research participants reflect the eligible population? Survey of participants recruited through a UK mental health Trust Ethnic inequalities in compulsory psychiatric hospital detentions during UK COVID-19 lockdowns: A Regression Discontinuity Design in time study Genetic overlap between functional impairment and depression and anxiety symptom severity: Evidence from the GLAD Study Online peer support in long-term conditions: Protocol for a feasibility randomised controlled trial Lexical Markers and Text Embedding Prediction of Depression Symptom Severity Universal credit trajectories among individuals who access secondary mental health services: analysis of linked data Speech reference intervals: an assessment of feasibility in depression symptom severity prediction Most Accurate Prevalence of PTSD and Common Mental Disorders in Healthcare Workers in England: A Two-Phase Epidemiological Survey Sociodemographic and psychosocial correlates of fatigue and chronic fatigue: A cross-sectional study from a South East London community survey Physical long-term conditions and the effectiveness of England's NHS Talking Therapies programme for working-age adults: findings from a South London borough Pre- and post-COVID 19 outbreak relationship between physical activity and depressive symptoms in Spanish adults with major depressive disorder: a secondary analysis of the RADAR-MDD cohort study Exploring the dynamic relationships between nocturnal heart rate, sleep disruptions, anxiety levels, and depression severity over time in recurrent major depressive disorder The Association Between Cognitive Functioning and Depression Severity: A Multiwave Longitudinal Remote Assessment Study Data Visualization Preferences in Remote Measurement Technology for Individuals Living With Depression, Epilepsy, and Multiple Sclerosis: Qualitative Study Assessing seasonal and weather effects on depression and physical activity using mobile health data ‘It hurts your heart’: frontline healthcare worker experiences of moral injury during the COVID-19 pandemic Long-term participant retention and engagement patterns in an app and wearable-based multinational remote digital depression study Personal independence payments among people who access mental health services: results from a novel data linkage Predictors of outcome following psychological therapy for depression and anxiety in an urban primary care service: A naturalistic Bayesian prediction modeling approach Towards a consensus roadmap for a new diagnostic framework for mental disorders Access to psychological therapies amongst patients with a mental health diagnosis in primary care: a data linkage study Etiological Factors and Symptom Triggers in Functional Motor Symptoms and Functional Seizures: A Pilot Investigation Real-time biopsychosocial antecedents and correlates of functional neurological symptoms in daily life: A pilot remote monitoring technology study Cost-utility analysis of transdiagnostic cognitive behavioural therapy for people with persistent physical symptoms in contact with specialist services evaluated in the PRINCE secondary trial Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls Accelarated immune ageing is associated with COVID-19 disease severity Automatic Assessment of the 2-Minute Walk Distance for Remote Monitoring of People with Multiple Sclerosis Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction Severe mental illness and infectious disease mortality: a systematic review and meta-analysis Reimagining Health and Care to Tackle the Rising Tide of Inequity, Multimorbidity, and Complex Conditions Cohort profile: working age adults accessing secondary mental health services in South London (UK) and benefits – a data linkage of electronic mental health records and benefits data The relationship between wearable-derived sleep features and relapse in Major Depressive Disorder LONGITUDINAL MODELING OF DEPRESSION SHIFTS USING SPEECH AND LANGUAGE Longitudinal Assessment of Seasonal Impacts and Depression Associations on Circadian Rhythm Using Multimodal Wearable Sensing: Retrospective Analysis Investigating psychobiological causes and mechanisms in functional seizures and functional motor symptoms: Study protocol Universal Credit receipt among working-age patients who are accessing specialist mental health services: results from a novel data linkage study Engagement With a Remote Symptom-Tracking Platform Among Participants With Major Depressive Disorder: Randomized Controlled Trial The Impact of COVID-19 Lockdown on Adults with Major Depressive Disorder from Catalonia: A Decentralized Longitudinal Study Long term mortality trends in people with severe mental illnesses and how COVID-19, ethnicity and other chronic mental health comorbidities contributed: a retrospective cohort study Deciphering seasonal depression variations and interplays between weather changes, physical activity, and depression severity in real-world settings: Learnings from RADAR-MDD longitudinal mobile health study Identifying depression-related topics in smartphone-collected free-response speech recordings using an automatic speech recognition system and a deep learning topic model Sickness absence and associations with sociodemographic factors, health risk behaviours, occupational stressors and adverse mental health in 40,343 UK police employees Interventions targeting social determinants of mental disorders and the sustainable development goals: A systematic review of reviews. Severe mental illness, race/ethnicity, multimorbidity and mortality following COVID-19 infection: nationally representative cohort study - ADDENDUM Personal independence payments among mental health service users: results from a novel data linkage View all publications
5 June 2025 IoPPN Researchers share details on second mental health UK Biobank survey With over 160,000 responses, the UK Biobank mental wellbeing survey allows researchers to better…