Biography
I am a medical statistician working primarily on clinical trials, ranging from phase I to phase IV. My road to medical statistics began as a mathematics undergraduate at Oxford University, followed by a PhD in infectious disease epidemiology at Imperial College London. I subsequently worked on a range of observational and randomised studies, with my methodological interests swaying my focus towards the latter.
Research interests
My main research interests are around making clinical trials more efficient through design and analysis. I am particularly interested in applying adaptive elements to trial designs where feasible, and in optimal stratification methods for smaller trials. On the analysis side, I am interested in covariate adjustment and missing data methods to optimally use available data. I am an advocate for using simulations to aid in trial design, particularly when using flexible designs and/or analyses that require type I error control to be demonstrated.
I am also interested in improving general understanding of medical statistics, both in medical education and across healthcare research. I am a Fellow of the Higher Education Academy, and have supervised several MPH student dissertation projects. I teach medical statistics to MBBS students, and run a BRC Survival Analysis course to healthcare researchers.
Expertise and public engagement
I am a member of the NIHR Improving Statistical Literacy Group, promoting better statistics in research community, and I am also a STEM ambassador.
Research
Trials Methodology Research Group
The Trials Methodology Research Group is focussed on improving the design, conduct and analysis of clinical trials for the benefit of participants, researchers, and others who use the evidence to make decisions about healthcare.
Supporting Parents And Kids Through Lockdown Experiences (SPARKLE) Trial
A randomised control trial evaluating whether a digital public health parenting intervention can help parents to manage their children’s behaviour problems.
Project status: Ongoing
Research
Trials Methodology Research Group
The Trials Methodology Research Group is focussed on improving the design, conduct and analysis of clinical trials for the benefit of participants, researchers, and others who use the evidence to make decisions about healthcare.
Supporting Parents And Kids Through Lockdown Experiences (SPARKLE) Trial
A randomised control trial evaluating whether a digital public health parenting intervention can help parents to manage their children’s behaviour problems.
Project status: Ongoing