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I lead the Hamilton Lab group, which is interested in brain function in white matter diseases such as Multiple Sclerosis, and Small Vessel Disease, which both lead to severe demyelination. We study the interactions between neurons, glial cells, immune cells and the vasculature using in vivo disease models, along with techniques such as electrophysiology (patch-clamping and compound action potential recording), confocal and 2-photon imaging, immunolabelling and electron microscopy. Using these techniques, we can combine our interests in studying receptor-mediated cellular communication with morphology, to determine how receptor activity regulates cell function. 

Please see my Research Staff Profile for more detail.

Key Publications:

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Key Collaborators:

  • Dr Catherine Hall, University of Sussed
  • Professor Kenneth Smith, University College London
  • Dr Diana Cash, King's College London
  • Professor David Attwell, University College London