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Neuroinflammation

 

 

Damage to the nervous system results in non-neuronal cells taking a stage-role. New and exciting roles continue to be discovered for brain-resident immune cells, such as microglia, and for macrophages that are constantly active and checking their environment for signs of injury or infection.

Microglia play key roles in chronic pain, synaptic pruning, and can ultimately mark individual synapses or whole cells for destruction. Genetic analysis indicates links between microglia and diseases such as Alzheimer’s and Parkinson’s diseases, chronic pain, and interactions between nerves and immune cells play key roles in the function of our gut. 

Our key questions:

  • What is the role of non-neuronal cells in chronic pain and in neurodegenerative disease?
  • How do neuroinflammatory changes alter neurons and their connections?
  • What is the relationship between immune cells and sensory nerves? How do glial cells interact with gut hormones and transmitters?

Click people profiles to discover their research:


Our research

Our research

Leading the world in understanding brain function and finding new treatments for patients

What is neuroscience?

What is neuroscience?

Neuroscience is the study of the nervous system, from structure to function, in health and disease

 

Discover more about Neuroscience at King’s

Centres

Centres

Specialist neuroscience centres, world-leading in understanding the brain at all stages of life

Resources

Resources

World-class neuroscience facilities, including MRI, neuroimaging equipment, and King's Brain Bank

PhD

PhD

Join a lively community of PhD students, learning from world-leading neuroscience researchers

 

News and events

Suffrage science

7 September 2020

The Suffrage Science Awards

The Suffrage Science awards, curated by the MRC London Institute of Medical Sciences, celebrate…