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King’s People

Dr Richard Amison

Academics
Supervisors

Lecturer in Pharmacology

Research subject areas

Pharmacology

Contact details

Biography

Dr Richard Amison is a Lecturer in Pharmacology within the School of Cancer and Pharmaceutical Science and is a member of the Sackler Institute of Pulmonary Pharmacology. After completing his undergraduate studies at Bristol University in 2010, Dr Amison obtained his PhD at King's College London (KCL) in 2014 which included working at the University of Perugia, Italy for 1 year. Dr Amison then continued at KCL in the Sackler Institute of Pulmonary Pharmacology to undertake post-doctoral studies before taking up an academic position in the School of Cancer and Pharmaceutical Science. The research focus of Dr Amison's group is in the understanding of the roles of platelets in the host immune response to bacterial infections. Dr Amison's research contributions have revealed that platelets are critical in the host response to infection not only through the mobilisation of other inflammatory cells but also through direct actions on the bacteria themselves as his research has shown a direct antimicrobial function of platelets. This might therefore offer opportunities for drugs intervention that may be used to 'boost' host defence.

Latest publications

Novel pharmacological therapies for the treatment of bronchial asthma
Amison, R. T. & Page, C. P., 1 Feb 2022, (Unpublished) In: Minerva Medica. 113, 1, p. 31-50 20 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.23736/S0026-4806.21.07559-5
Stimulation of the Platelet P2Y(1) Receptor by Endogenous Agonists Leads to a Dichotomy in Platelet Function
Arkless, K., Amison, R., Shankar-Hari, M., Page, C. & Pitchford, S., Jan 2021, In: British journal of pharmacology. 178, 2, p. 381-382 Research output: Contribution to journal › Meeting Abstract › peer-review
Red Blood Cells Elicit Platelet-Dependent Neutrophil Recruitment into Lung Airspaces
Arnold, S., Shah, S. A., Cleary, S. J., O'shaughnessy, B. G., Amison, R. T., Arkless, K., Page, C. P. & Pitchford, S. C., 9 Dec 2020, (E-pub ahead of print) In: Shock. 56, 2, 278 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1097/SHK.0000000000001705
A Pleurocidin Analogue with Greater Conformational Flexibility, Enhanced Antimicrobial Potency and in vivo Therapeutic Efficacy
Manzo, G., Hind, C. K., Ferguson, P., Amison, R., Hodgson-Casson, A., Ciazynska, K., Weller, B., Clarke, M., Lam, C., Man, R., O'Shaughnessy, B., Clifford, M., Bui, T., Drake, A., Atkinson, A., Lam, J., Pitchford, S., Page, C., Phoenix, D., Lorenz, C., & 2 othersSutton, J. M. & Mason, J., 31 Dec 2020, In: Communications Biology. 3, 1, 697. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s42003-020-01420-3
Animal models of mechanisms of SARS-CoV-2 infection and COVID-19 pathology
Cleary, S. J., Pitchford, S. C., Amison, R. T., Carrington, R., Robaina Cabrera, C. L., Magnen, M., Looney, M. R., Gray, E. & Page, C. P., 1 Nov 2020, In: British Journal of Pharmacology. 177, 21, p. 4851-4865 15 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1111/bph.15143
The small quinolone derived compound HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo.
Amison, R. T., Faure, M-E. Y. L., O'Shaughnessy, B. G., Bruce, K., Hu, Y., Coates, A. & Page, C. P., 1 Apr 2020, In: Pulmonary pharmacology & therapeutics. 61, 101884. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.pupt.2019.101884
Pharmacological strategies for targeting platelet activation in asthma
Pitchford, S., Cleary, S., Arkless, K. & Amison, R., 1 Jun 2019, In: Current Opinion in Pharmacology. 46, p. 55-64 10 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1016/j.coph.2019.03.012
LPS-Induced Lung Platelet Recruitment Occurs Independently from Neutrophils, PSGL-1, and P-selectin
Cleary, S. J., Hobbs, C., Amison, R., Arnold, S., O'Shaughnessy, B. G., Lefrançais, E., Mallavia, B., Looney, M. R., Page, C. P. & Pitchford, S. C., 1 Aug 2019, In: American Journal of Respiratory Cell and Molecular Biology. 61, 2, p. 232-243 12 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1165/rcmb.2018-0182OC
A dichotomy in platelet activation: Evidence of different functional platelet responses to inflammatory versus haemostatic stimuli
Petito, E., Amison, R. T., Piselli, E., Shah, S., Momi, S., Pitchford, S. C., Gresele, P. & Page, C. P., 25 Oct 2018, (E-pub ahead of print) In: Thrombosis Research. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.thromres.2018.10.019
Diverse signaling of the platelet P2Y1 receptor leads to a dichotomy in platelet function
Amison, R. T., Jamshidi, S., Rahman, K. M., Page, C. P. & Pitchford, S. C., 11 Mar 2018, (E-pub ahead of print) In: European Journal of Pharmacology. p. 58-70 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.ejphar.2018.03.014

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IPS-studentships

13 October 2020

Six new Studentships for Institute of Pharmaceutical Science

The School of Cancer & Pharmaceutical Science are pleased to announce that there are six new…