Mr Sami Sultan
Sami has a long standing interest in the field of immunology, with a particular interest in the interactions between immune and non-immune cells. He obtained a BSc in Biomedical science from Brunel University London, and as a summer intern in the laboratory of Dr Uday Kishore he investigated how innate immune molecules modulate cancer cells (Kaur et al., 2016). Subsequently, Sami studied for a MSc in Immunology at Imperial College London. Working within the Strid/Botto lab, he investigated the role of complement in an in vitro skin cancer model.
The focus of Sami’s project is to understand how macrophages interact with resident muscle stem cells, and to dissect the consequential effects of these communications in the context of muscle regeneration. Combining live cell imaging, with expression profiling of cells and pharmacological and genetic manipulations, he seeks to determine how signalling between these cell types affects their behavior and programming. Sami is funded by the NC3Rs and he concurrently is investigating the practicality of using live cell imaging in zebrafish as a means to replace, reduce and refine the use of animals in the field of regenerative biology.