Dr Shahram Kordasti Academics Supervisors Reader and Group Leader in Applied Cancer Immunopathology Research subject areas Cancer Immunology Contact details shahram.kordasti@kcl.ac.uk +44 (0) 20 7848 8028 @KordastiL @SKordasti
Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells Couch, A., Solomon, S., Rafagnin Duarte, R. R., Marrocu, A., Sun, Y., Sichlinger, L., Matuleviciute, R., Dutan Polit, L., Hanger, B., Brown, A., Kordasti, S., Srivastava, D. & Vernon, A., 11 Feb 2023, In: Brain Behaviour and Immunity. https://doi.org/10.1016/j.bbi.2023.02.007, https://doi.org/10.1016/j.bbi.2023.02.007. Research output: Contribution to journal › Article › peer-review Predicting Progression Free Survival after Systemic Therapy in Advanced Head and Neck Cancer: Bayesian regression and Model development Barber, P. R., Mustapha, R., Flores-Borja, F., Alfano, G., Ng, K., Weitsman, G., Dolcetti, L., Mohamed, A., Wong, F., Vicencio Bustamante, J., Galazi, M., Opzoomer, J., Arnold, J., Thavaraj, S., Kordasti, S., Doyle, J., Greenberg, J., Dillon, M., Harrington, K. J., Forster, M., & 2 othersCoolen, A. CC. & Ng, T., 23 Dec 2022, (E-pub ahead of print) In: eLife. In press Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.7554/eLife.73288 Regulatory T cell niche in the bone marrow, a new player in Haematopoietic stem cell transplantation Ashman, J., Mutsonziwa, N., Romano, M., Kordasti, S., Lombardi, G. & Shangaris, P., 31 Oct 2022, In: Blood Reviews. p. 101030 101030. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.blre.2022.101030 Chronic myeloid leukaemia patients at diagnosis and resistant to tyrosine kinase inhibitor therapy display exhausted T-cell phenotype Harrington, P., Dillon, R., Radia, D., McLornan, D., Woodley, C., Asirvatham, S., Raj, K., Curto-Garcia, N., Saunders, J., Kordasti, S., Harrison, C. & de Lavallade, H., Sep 2022, In: British Journal of Haematology. 198, 6, p. 1011-1015 5 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1111/bjh.18302 Hostile Takeover: Tregs expand in IFN-γ-rich AML microenvironment Ferrell, P. B. & Kordasti, S., 15 Jul 2022, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 28, 14, p. 2986-2988 3 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1158/1078-0432.CCR-22-1030 A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling Goldberg, R., Clough, J. N., Roberts, L. B., Sanchez, J., Kordasti, S., Petrov, N., Hertweck, A., Lorenc, A., Jackson, I., Tasker, S., Appios, A., Omer, O., Parkes, M., Prescott, N., Jenner, R. G., Irving, P. M. & Lord, G. M., 18 Dec 2021, In: Journal of Crohn's & colitis. 15, 12, p. 2054-2065 12 p., jjab103. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/ecco-jcc/jjab103 Erratum: Repeated vaccination against SARS-CoV-2 elicits robust polyfunctional T cell response in allogeneic stem cell transplantation recipients (Cancer Cell (2021) 39(11) (1448–1449), (S1535610821005444), (10.1016/j.ccell.2021.10.002)) Harrington, P., Doores, K. J., Saha, C., Saunders, J., Child, F., Dillon, R., Saglam, S., Raj, K., McLornan, D., Avenoso, D., Kordasti, S., O'Reilly, A., Espehana, A., Lechmere, T., Khan, H., Malim, M. H., Harrison, C., Mehra, V. & de Lavallade, H., 13 Dec 2021, In: CANCER CELL. 39, 12, p. 1654 1 p. Research output: Contribution to journal › Comment/debate › peer-review. DOIs: https://doi.org/10.1016/j.ccell.2021.11.011 Single dose of BNT162b2 mRNA vaccine against SARS-CoV-2 induces high frequency of neutralising antibody and polyfunctional T-cell responses in patients with myeloproliferative neoplasms Harrington, P., de Lavallade, H., Doores, K. J., O'Reilly, A., Seow, J., Graham, C., Lechmere, T., Radia, D., Dillon, R., Shanmugharaj, Y., Espehana, A., Woodley, C., Saunders, J., Curto-Garcia, N., O'Sullivan, J., Raj, K., Kordasti, S., Malim, M. H., Harrison, C. N. & McLornan, D. P., Dec 2021, In: Leukemia. 35, 12, p. 3573-3577 5 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41375-021-01300-7 Repeated vaccination against SARS-CoV-2 elicits robust polyfunctional T cell response in allogeneic stem cell transplantation recipients Harrington, P., Doores, K. J., Saha, C., Saunders, J., Child, F., Dillon, R., Saglam, S., Raj, K., McLornan, D., Avenoso, D., Kordasti, S., O'Reilly, A., Espehana, A., Lechmere, T., Khan, H., Malim, M. H., Harrison, C., Mehra, V. & de Lavallade, H., 8 Nov 2021, In: CANCER CELL. 39, 11, p. 1448-1449 2 p. Research output: Contribution to journal › Letter › peer-review. DOIs: https://doi.org/10.1016/j.ccell.2021.10.002 Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression Opzoomer, J. W., Anstee, J. E., Dean, I., Hill, E. J., Bouybayoune, I., Caron, J., Muliaditan, T., Gordon, P., Sosnowska, D., Nuamah, R., Pinder, S. E., Ng, T., Dazzi, F., Kordasti, S., Withers, D. R., Lawrence, T. & Arnold, J. N., 5 Nov 2021, In: Science Advances. 7, 45, p. eabg9518 eabg9518. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1126/sciadv.abg9518 View all publications
14 June 2021 New open-source easy-to-use resource for the analysis of high-dimensional cytometry data launches ImmunoCluster provides a computational framework for the non-specialist to profile complex…