Professor Simon Ameer-Beg Academics Supervisors Professor in Optical Oncology Research subject areas Biomedical and life sciences Contact details simon.ameer-beg@kcl.ac.uk +44 (0) 20 7848 6558 @femtoscopist
In situ FRET-based localization of the N-terminus of myosin binding protein-C in heart muscle cells Chandler, J., Treacy, C., Ameer-Beg, S., Ehler, E., Irving, M. & Kampourakis, T., 15 Feb 2023, In: Proceedings of the National Academy of Sciences of the United States of America. Research output: Contribution to journal › Article › peer-review Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans Vicencio Bustamante, J., Evans, R., Green, R., An, Z., Deng, J., Treacy, C., Mustapha, R., Monypenny of Pitmilly, J., Costoya, C., Lawler, K., Ng, K., Desouza, K., Coban, O., Gomez, V., Clancy, J., Chen, SH., Chalk, A., Wong, F., Gordon, P., Savage, C., & 20 othersGomes, C., Pan, T., Alfano, G., Dolcetti, L., Chan, J. N. E., Florez-Borja, F., Barber, P., Weitsman, G., Sosnowska, D., Capone, E., Iacobelli, S., Hochhauser, D., Hartley, J., Parsons, M., Arnold, J., Ameer-Beg, S., Quezada, S. A., Yarden, Y., Sala, G. & Ng, T., 28 Mar 2022, In: Cell Death & Disease. 13, 3, 274 . Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41419-022-04701-3 Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration Krause, M., Stramer, B., Ameer-Beg, S., Poland, S., Levitt, J., Marcotti, S., Köchl, R., Pallett, T., Law, A-L., Binti Abd Jalal, S. & Mosis, F., 28 Sep 2021, In: Nature Communications. 12, 1, 1 p., 5687. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41467-021-25916-6 Quantitative real-time imaging of intracellular FRET biosensor dynamics using rapid multi-beam confocal FLIM Levitt, J. A., Poland, S. P., Krstajić, N., Pfisterer, K., Erdogan, A., Barber, P. R., Parsons, M., Henderson, R. & Ameer-Beg, S., 1 Dec 2020, In: Scientific Reports. 10, 1, 5146 . Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1038/s41598-020-61478-1 Special issue on fluorescence lifetime imaging (FLIM): from fundamentals to applications Ameer-Beg, S., Suhling, K. & Kuimova, M., 6 Oct 2020, In: Methods and applications in fluorescence. 8, 4, p. 40401 1 p., abad19. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1088/2050-6120/abad19 FMNL2 regulates dynamics of fascin in filopodia Pfisterer, K., Levitt, J., Lawson, C., Marsh, R., Heddleston, J., Wait, E., Ameer-Beg, S., Cox, S. & Parsons, M., 4 May 2020, In: Journal of Cell Biology. 219, 5, e201906111. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1083/jcb.201906111 Adaptive optics for time-resolved Förster Resonance Energy Transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM) in vivo Ameer-Beg, S., Poland, S. P. & Devauges, V. J. R. E., 14 Feb 2020, (Accepted/In press) In: Optics Letters. Research output: Contribution to journal › Article › peer-review Flow cytometry visualization and real-Time processing with a CMOS SPAD array and high-speed hardware implementation algorithm Mai, H., Poland, S. P., Mattioli Della Rocca, F., Treacy, C., Aluko, J., Nedbal, J., Erdogan, A. T., Gyongy, I., Walker, R., Ameer-Beg, S. M. & Henderson, R. K., 1 Jan 2020, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVIII. Farkas, D. L. & Tarnok, A. (eds.). SPIE, 112430S. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11243). Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review. DOIs: https://doi.org/10.1117/12.2544759 TNFR1 membrane reorganization promotes distinct modes of TNFα signaling Morton, P. E., Perrin, C., Levitt, J., Matthews, D. R., Marsh, R. J., Pike, R., McMillan, D., Maloney, A., Poland, S., Ameer-Beg, S. & Parsons, M., 30 Jul 2019, In: Science Signaling. 12, 592, eaaw2418. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1126/scisignal.aaw2418 Multifocal multiphoton volumetric imaging approach for high-speed time-resolved Förster resonance energy transfer imaging in vivo Poland, S. P., Chan, G. K., Levitt, J. A., Krstajić, N., Erdogan, A. T., Henderson, R. K., Parsons, M. & Ameer-Beg, S. M., 15 Dec 2018, In: Optics Letters. 43, 24, p. 6057-6060 4 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1364/OL.43.006057 View all publications
28 September 2021 Advanced microscopy study reveals molecular details of tight control of cell migration New research provides novel insights with potentially important implications for our understanding…