Professor Snezhana Oliferenko Academics Supervisors Professor of Evolutionary Cell Biology Research subject areas Biomedical and life sciences Contact details snezhana.oliferenko@kcl.ac.uk
Adaptation of eukaryotic membrane homeostasis to species-specific cellular lipid landscapes Visualizing Phosphatidic Acid and Diacylglycerol at the Nuclear Envelope in Fission Yeast Characterization and comparison of Schizosaccharomyces pombe cdc15 temperature-sensitive mutants Horizontal acquisition of prokaryotic hopanoid biosynthesis reorganizes membrane physiology driving lifestyle innovation in a eukaryote Mitosis: An expanded view of mitotic mechanisms that arose in evolution Horizontal gene transfer-initiated reorganization of lipid metabolism drives lifestyle innovation in a eukaryote The Gene Ontology knowledgebase in 2023 Telomere-to-telomere Schizosaccharomyces japonicus genome assembly reveals hitherto unknown genome features Schizosaccharomyces versatilis represents a distinct evolutionary lineage of fission yeast Revised fission yeast gene and allele nomenclature guidelines for machine readability Peroxisomal compartmentalization of amino acid biosynthesis reactions imposes an upper limit on compartment size Optimisation of energy production and central carbon metabolism in a non-respiring eukaryote Diacylglycerol at the inner nuclear membrane fuels nuclear envelope expansion in closed mitosis mNG-tagged fusion proteins and nanobodies to visualize tropomyosins in yeast and mammalian cells JaponicusDB: Rapid deployment of a model organism database for an emerging model species Cell Biology: An Open Solution for Closed Mitosis The principles of cellular geometry scaling ESCRT-III/Vps4 controls heterochromatin-nuclear envelope attachments Delineating the Rules for Structural Adaptation of Membrane-Associated Proteins to Evolutionary Changes in Membrane Lipidome Understanding eukaryotic chromosome segregation from a comparative biology perspective Cellular geometry scaling ensures robust division site positioning Actin turnover maintains actin filament homeostasis during cytokinetic ring contraction Component Turnover in the Cytokinetic Ring Maintains Organizational Homeostasis and Tension Production Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction Mixing and matching nuclear envelope remodeling and spindle assembly strategies in the evolution of mitosis Temporal Regulation of Lipin Activity Diverged to Account for Differences in Mitotic Programs Comparative biology of cell division in the fission yeast clade. Rewiring of Cellular Division Site Selection in Evolution of Fission Yeasts A strong expression of CD44-6v correlates with shorter survival of patients with acute myeloid leukemia Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton Hyaluronic acid (HA) binding to CD44 activates Rac1 and induces lamellipodia outgrowth Variant isoforms of CD44 are required in early thymocyte development Cell cycle: the Flp side of Cdc14 The Localization of the Integral Membrane Protein Cps1p to the Cell Division Site is Dependent on the Actomyosin Ring and the Septation-Inducing Network in Schizosaccharomyces pombe Astral microtubules monitor metaphase spindle alignment in fission yeast Cytokinesis: relative alignment of the cell division apparatus and the mitotic spindle A potential tension-sensing mechanism that ensures timely anaphase onset upon metaphase spindle orientation The fission yeast transforming acidic coiled coil-related protein Mia1p/Alp7p is required for formation and maintenance of persistent microtubule-organizing centers at the nuclear envelope The spindle pole bodies facilitate nuclear envelope division during closed mitosis in fission yeast Assembly of microtubules and actomyosin rings in the absence of nuclei and spindle pole bodies revealed by a novel genetic method Hsp70-Hsp40 chaperone complex functions in controlling polarized growth by repressing Hsf1-driven heat stress-associated transcription Tts1, the fission yeast homologue of the TMEM33 family, functions in NE remodeling during mitosis Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function Partitioning and remodeling of the Schizosaccharomyces japonicus mitotic nucleus require chromosome tethers The actomyosin ring recruits early secretory compartments to the division site in fission yeast Cytokinesis: Catch and drag Positioning cytokinesis Nucleocytoplasmic Shuttling of the TACC Protein Mia1p/Alp7p Is Required for Remodeling of Microtubule Arrays during the Cell Cycle The Fission Yeast TACC Protein Mia1p Stabilizes Microtubule Arrays by Length-Independent Crosslinking The Cortical ER Network Limits the Permissive Zone for Actomyosin Ring Assembly View all publications
16 April 2025 Beneficial bacterial gene rewires yeast biology New research has shown that the transfer of genes from bacteria to more complex organisms like yeast…