Dr Sophia Tsoka Academics Reader in Bioinformatics Research subject areas Computer science Contact details +44 020 7848 1056 sophia.tsoka@kcl.ac.uk
Cancer Grade Model: a multi-gene machine learning-based risk classification for improving prognosis in breast cancer Amiri Souri, E., Chenoweth, A., Cheung, A., Karagiannis, S. N. & Tsoka, S., 31 Aug 2021, In: British Journal of Cancer, Nature Research. 125, 5, p. 748-758 11 p. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1038/s41416-021-01455-1 Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes In Triple-Negative Breast Cancer Harris, R. J., Cheung, A., Ng, J. C. F., Laddach, R., Chenoweth, A. M., Crescioli, S., Fittall, M., Dominguez-Rodriguez, D., Roberts, J., Levi, D., Liu, F., Alberts, E., Quist, J., Santaolalla, A., Pinder, S. E., Gillett, C., Hammar, N., Irshad, S., van Hemelrijck, M., Dunn-Walters, D. K. & 7 others, Fraternali, F., Spicer, J. F., Lacy, K. E., Tsoka, S., Grigoriadis, A., Tutt, A. N. J. & Karagiannis, S. N., 15 Aug 2021, In: Cancer Research. 81, 16, p. 4290-4304 15 p. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1158/0008-5472.CAN-20-3773https://doi.org/10.1158/0008-5472.CAN-20-3773 Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes The MAGIC Investigators & The GIANT consortium, 7 Aug 2014, In: PLoS Genetics. 10, 8, e1004517. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1371/journal.pgen.1004517 Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: treatment of melanoma and immune mechanisms of action Willsmore, Z. N., Coumbe, B. G. T., Crescioli, S., Reci, S., Gupta, A., Harris, R. J., Chenoweth, A., Chauhan, J., Bax, H. J., McCraw, A., Cheung, A., Osborn, G., Hoffmann, R. M., Nakamura, M., Laddach, R., Geh, J. L. C., Ross, A. M., Healy, C., Tsoka, S., Spicer, J. F. & 4 others, Josephs, D. H., Papa, S., Lacy, K. E. & Karagiannis, S. N., Mar 2021, In: European Journal of Immunology. 51, 3, p. 544-556 13 p. Research output: Contribution to journal - Review article - peer-review. DOIs: https://doi.org/10.1002/eji.202048747 B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies Willsmore, Z. N., Harris, R. J., Crescioli, S., Hussein, K., Kakkassery, H., Thapa, D., Cheung, A., Chauhan, J., Bax, H. J., Chenoweth, A., Laddach, R., Osborn, G., McCraw, A., Hoffmann, R. M., Nakamura, M., Geh, J. L., MacKenzie-Ross, A., Healy, C., Tsoka, S., Spicer, J. F. & 4 others, Papa, S., Barber, L., Lacy, K. E. & Karagiannis, S. N., 25 Jan 2021, In: Frontiers in Immunology. 11, 622442. Research output: Contribution to journal - Review article - peer-review. DOIs: https://doi.org/10.3389/fimmu.2020.622442 IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype Nakamura, M., Souri, E. A., Osborn, G., Laddach, R., Chauhan, J., Stavraka, C., Lombardi, S., Black, A., Khiabany, A., Khair, D. O., Figini, M., Winship, A., Ghosh, S., Montes, A., Spicer, J. F., Bax, H. J., Josephs, D. H., Lacy, K. E., Tsoka, S. & Karagiannis, S. N., 15 Nov 2020, In: Cancers. 12, 11, p. 1-19 19 p., 3376. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.3390/cancers12113376 Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites Ottman, N., Barrientos-Somarribas, M., Fyhrquist, N., Alexander, H., Wisgrill, L., Olah, P., Tsoka, S., Greco, D., Levi-Schaffer, F., Soumelis, V., Schröder, J. M., Kere, J., Nestle, F. O., Barker, J., Ranki, A., Lauerma, A., Homey, B., Andersson, B. & Alenius, H., 2020, (Accepted/In press) In: Allergy: European Journal of Allergy and Clinical Immunology. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.1111/all.14606 Identification of Important Biological Pathways for Ischemic Stroke Prediction through a Mathematical Programming Optimisation Model-DIGS Chen, Y., Theofilatos, K., Papageorgiou, L. G. & Tsoka, S., 22 May 2020, Proceedings of the 2020 12th International Conference on Bioinformatics and Biomedical Technology, ICBBT 2020. Association for Computing Machinery, p. 25-31 7 p. (ACM International Conference Proceeding Series). Research output: Chapter in Book/Report/Conference proceeding - Conference paper - peer-review. DOIs: https://doi.org/10.1145/3405758.3405767 Cancer Classification through a Hybrid Machine Learning Approach. Amiri Souri, E. & Tsoka, S., 2020, Best Paper Award at The Twelfth International Conference on Bioinformatics, Biocomputational Systems and Biotechnologies. IARIA, p. 20-27 Research output: Chapter in Book/Report/Conference proceeding - Conference paper - peer-review PHI-Nets: A Network Resource for Ascomycete Fungal Pathogens to Annotate and Identify Putative Virulence Interacting Proteins and siRNA Targets Janowska-Sejda, E. I., Lysenko, A., Urban, M., Rawlings, C., Tsoka, S. & Hammond-Kosack, K. E., 6 Dec 2019, In: Frontiers in microbiology. 10, 2721. Research output: Contribution to journal - Article - peer-review. DOIs: https://doi.org/10.3389/fmicb.2019.02721 View all publications