Dr Subhankar Mukhopadhyay Academics Senior Lecturer in Innate Immunity Contact details subhankar.mukhopadhyay@kcl.ac.uk +44 (0) 20 7188 8711
Plasma Membrane Receptors of Tissue Macrophages: Functions and Role in Pathology Gordon, S., Plüddemann, A. & Mukhopadhyay, S., 22 Feb 2020, In : Journal of Pathology. Research output: Contribution to journal - Review article. DOIs: https://doi.org/10.1002/path.5404 Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2 Mukhopadhyay, S., Heinz, E., Porreca, I., Alasoo, K., Yeung, A., Yang, H. T., Schwerd, T., Forbester, J. L., Hale, C., Agu, C. A., Choi, Y. H., Rodrigues, J., Capitani, M., Jostins-Dean, L., Thomas, D. C., Travis, S., Gaffney, D., Skarnes, W. C., Thomson, N., Uhlig, H. H. & 2 others, Dougan, G. & Powrie, F., 1 Feb 2020, In : The Journal of experimental medicine. 217, 2, e20180649. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1084/jem.20180649 GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump Schneditz, G., Elias, J. E., Pagano, E., Zaeem Cader, M., Saveljeva, S., Long, K., Mukhopadhyay, S., Arasteh, M., Lawley, T. D., Dougan, G., Bassett, A., Karlsen, T. H., Kaser, A. & Kaneider, N. C., 1 Jan 2019, In : Science Signaling. 12, 562, eaau9048. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1126/scisignal.aau9048 Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis Ryzhakov, G., West, N. R., Franchini, F., Clare, S., Ilott, N. E., Sansom, S. N., Bullers, S. J., Pearson, C., Costain, A., Vaughan-Jackson, A., Goettel, J. A., Ermann, J., Horwitz, B. H., Buti, L., Lu, X., Mukhopadhyay, S., Snapper, S. B. & Powrie, F., 1 Dec 2018, In : Nature Communications. 9, 1, 3797. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41467-018-06085-5 Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells Forbester, J. L., Lees, E. A., Goulding, D., Forrest, S., Yeung, A., Speak, A., Clare, S., Coomber, E. L., Mukhopadhyay, S., Kraiczy, J., Schreiber, F., Lawley, T. D., Hancock, R. E. W., Uhlig, H. H., Zilbauer, M., Powrie, F. & Dougan, G., 2 Oct 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 40, p. 10118-10123 6 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1073/pnas.1811866115 New variant of multidrug-resistant Salmonella enterica serovar typhimurium associated with invasive disease in immunocompromised patients in Vietnam Mather, A. E., Phuong, T. L. T., Gao, Y., Clare, S., Mukhopadhyay, S., Goulding, D. A., Do Hoang, N. T., Tuyen, H. T., Lan, N. P. H., Thompson, C. N., Trang, N. H. T., Carrique-Mas, J., Tue, N. T., Campbell, J. I., Rabaa, M. A., Thanh, D. P., Harcourt, K., Hoa, N. T., Trung, N. V., Schultsz, C. & 12 others, Perron, G. G., Coia, J. E., Brown, D. J., Okoro, C., Parkhill, J., Thomson, N. R., Chau, N. V. V., Thwaites, G. E., Maskell, D. J., Dougan, G., Kenney, L. J. & Baker, S., 4 Sep 2018, In : Mbio. 9, 5, e01056-18. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1128/mBio.01056-18 Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response Alasoo, K., Rodrigues, J., Mukhopadhyay, S., Knights, A. J., Mann, A. L., Kundu, K., Hale, C., Dougan, G. & Gaffney, D. J., 1 Mar 2018, In : Nature Genetics. 50, 3, p. 424-431 8 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41588-018-0046-7 A simple multistep protocol for differentiating human induced pluripotent stem cells into functional macrophages Mukherjee, C., Hale, C. & Mukhopadhyay, S., 1 Jan 2018, Methods in Molecular Biology. Humana Press Inc, p. 13-28 16 p. (Methods in Molecular Biology; vol. 1784). Research output: Chapter in Book/Report/Conference proceeding - Chapter. DOIs: https://doi.org/10.1007/978-1-4939-7837-3_2 Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity Thomas, D. C., Clare, S., Sowerby, J. M., Pardo, M., Juss, J. K., Goulding, D. A., van der Weyden, L., Storisteanu, D., Prakash, A., Espéli, M., Flint, S., Lee, J. C., Hoenderdos, K., Kane, L., Harcourt, K., Mukhopadhyay, S., Umrania, Y., Antrobus, R., Nathan, J. A., Adams, D. J. & 7 others, Bateman, A., Choudhary, J. S., Lyons, P. A., Condliffe, A. M., Chilvers, E. R., Dougan, G. & Smith, K. G. C., 1 Apr 2017, In : Journal of Experimental Medicine. 214, 4, p. 1111-1128 18 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1084/jem.20161382 C13orf31 (FAMIN) is a central regulator of immunometabolic function Cader, M. Z., Boroviak, K., Zhang, Q., Assadi, G., Kempster, S. L., Sewell, G. W., Saveljeva, S., Ashcroft, J. W., Clare, S., Mukhopadhyay, S., Brown, K. P., Tschurtschenthaler, M., Raine, T., Doe, B., Chilvers, E. R., Griffin, J. L., Kaneider, N. C., Floto, R. A., D'amato, M., Bradley, A. & 3 others, Wakelam, M. J. O., Dougan, G. & Kaser, A., 19 Aug 2016, In : Nature Immunology. 17, 9, p. 1046-1056 11 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/ni.3532 View all publications
5 December 2019 Research identifies link in the treatment of inflammatory bowel disease New research identifies molecules that maintain the balance in our gut.