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Tim  Hubbard

Professor Tim Hubbard

Professor of Bioinformatics

Biography

I studied Biochemistry at the University of Cambridge, followed by a PhD in Protein Design at the Department of Crystallography,‭ ‬Birkbeck College,‭ University of ‬London. Following a postdoctoral fellowship at the Protein Engineering Research Institute in Osaka under the EU scientific training program in Japan,‭ I returned to Cambridge in 1990 as a Zeneca Fellow at the MRC‭‭ ‬Centre for Protein Engineering to work on protein folding, ‬classification and design.

I co-founded SCOP‭ (‬the Structural Classification of Proteins database‭)‬ and developed algorithms to make protein structure predictions and assess their accuracy and to calibrate the reliability of sequence alignment methods.‭ ‬I was one of the most successful participants in the first CASP‭ (‬Critical Assessment of Structure Prediction‭) ‬competition in‭ ‬1994‭ ‬and a co-organiser of subsequent CASP competitions‭ (‬CASP2-CASP7‭) ‬until‭ ‬2007.

In‭ ‬1997‭ ‬I joined the Wellcome Trust Sanger Institute to become Head of Human Genome Analysis, where I was one of the organisers of the sequencing of the human genome. In 1999 I co-founded the Ensembl project to analysis, organise and provide access to the human genome. From 2007 I led the GENCODE project to annotate the structure of all human genes, initially as part of the ENCODE project. I‭ was the Sanger Institute PI of the Genome Reference Consortium,‭ ‬which is responsible for reference genome sequences of human,‭ ‬mouse and zebrafish. I became Head of the Informatics division from‭ ‬2007. After the announcement of the 100,000 genomes project 2012 ‬I was seconded part-time as a specialist advisor for genomics to NHS England leading up to the creation of Genomics England.

In October 2013 I was appointed Professor of Bioinformatics and Head of the Department of Medical & Molecular Genetics at King's College London and Director of Bioinformatics for King's Health Partners with a part-time secondment as Head of Genome Analysis at Genomics England.

In 2018 I was also appointed as Associate Director (King's) for the Health Data Research London Site.

    News

    Professor Tim Hubbard announced as the next ELIXIR Director

    Professor Tim Hubbard will be responsible for leading ELIXIR’s technical and scientific programmes

    Tim Hubbard 780x450

    Professor Tim Hubbard appointed to prestigious WHO Technical Advisory Group

    Professor Tim Hubbard has become one of fifteen appointees to the new Technical Advisory Group (TAG) on Genomics.

    Tim Hubbard 780x450

    Features

    Sequencing, now more than ever

    65 years after the death of Rosalind Franklin and 70 years since the publication of the structure of DNA, the impact of the discovery continues to grow. The...

    Genome sequence

    Rosalind Franklin: How her legacy lives on

    This weekend, July 25th, marks 100 years since the birth of Rosalind Franklin, one of history’s leading scientists. While working at King’s, Franklin famously...

    DNA-Correct hero banner 1903 x558

    Utopia Now! Local young people set out their visions for the future

    King’s researchers help young people explore their hopes and fears for the future

    Futuristic streetscape by Utopia Now! competition winner Laura Hack

    The secret of life - part 2: AI provides a solution to the protein folding problem

    AI provides a solution to the protein folding problem which scientists have been hunting for 50 years

    Banner image of proteins

      News

      Professor Tim Hubbard announced as the next ELIXIR Director

      Professor Tim Hubbard will be responsible for leading ELIXIR’s technical and scientific programmes

      Tim Hubbard 780x450

      Professor Tim Hubbard appointed to prestigious WHO Technical Advisory Group

      Professor Tim Hubbard has become one of fifteen appointees to the new Technical Advisory Group (TAG) on Genomics.

      Tim Hubbard 780x450

      Features

      Sequencing, now more than ever

      65 years after the death of Rosalind Franklin and 70 years since the publication of the structure of DNA, the impact of the discovery continues to grow. The...

      Genome sequence

      Rosalind Franklin: How her legacy lives on

      This weekend, July 25th, marks 100 years since the birth of Rosalind Franklin, one of history’s leading scientists. While working at King’s, Franklin famously...

      DNA-Correct hero banner 1903 x558

      Utopia Now! Local young people set out their visions for the future

      King’s researchers help young people explore their hopes and fears for the future

      Futuristic streetscape by Utopia Now! competition winner Laura Hack

      The secret of life - part 2: AI provides a solution to the protein folding problem

      AI provides a solution to the protein folding problem which scientists have been hunting for 50 years

      Banner image of proteins