Professor Toby Lawrence Academics Professor of Inflammation Biology Contact details toby.lawrence@kcl.ac.uk +44 (0) 20 7848 8630
Targeting stat3 and stat5 in tumor-associated immune cells to improve immunotherapy 01 December 2019 Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression 07 October 2019 Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression 04 June 2019 Precise and rapid validation of candidate gene by allele specific knockout with CRISPR/Cas9 in wild mice 01 January 2019 Autophagy in dendritic cells 26 March 2018 GADD45β Loss Ablates Innate Immunosuppression in Cancer 01 March 2018 Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone 28 November 2017 The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation 08 June 2017 Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of 'soluble CD163' in plasma 13 January 2017 High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling 10 January 2017
2 August 2019 Scientists find potential 'magic bullet' for treating tumours Researchers have found a therapy to reduce the size of tumours where previous drugs have failed.