Professor Toby Lawrence Professor Toby Lawrence Academics Supervisors Professor of Inflammation Biology Contact details toby.lawrence@kcl.ac.uk +44 (0) 20 7848 8630
Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression Opzoomer, J. W., Anstee, J. E., Dean, I., Hill, E. J., Bouybayoune, I., Caron, J., Muliaditan, T., Gordon, P., Sosnowska, D., Nuamah, R., Pinder, S. E., Ng, T., Dazzi, F., Kordasti, S., Withers, D. R., Lawrence, T. & Arnold, J. N., 5 Nov 2021, In: Science Advances. 7, 45, p. eabg9518 eabg9518. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1126/sciadv.abg9518 Macrophages orchestrate the expansion of a pro-angiogenic perivascular niche during cancer progression Opzoomer, J. W., Anstee, J. E., Dean, I., Hill, E. J., Bouybayoune, I., Caron, J., Muliaditan, T., Gordon, P., Sosnowska, D., Nuamah, R., Pinder, S. E., Ng, T., Dazzi, F., Kordasti, S., Withers, D. R., Lawrence, T. & Arnold, J. N., 3 Nov 2021, In: Science Advances. Research output: Contribution to journal › Article › peer-review The Role of Plasmacytoid Dendritic Cells in Cancers Zhou, B., Lawrence, T. & Liang, Y., 19 Oct 2021, In: Frontiers in Immunology. 12, 749190. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3389/fimmu.2021.749190 An inducible model for specific neutrophil depletion by diphtheria toxin in mice Chao, T., Lu, L., Zhang, L., Huang, R., Liu, Z., Zhou, B., Kong, E., Zhang, Z., Lawrence, T. & Liang, Y., Aug 2021, In: Science China Life Sciences. 64, 8, p. 1227-1235 9 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1007/s11427-020-1839-3 NF-kB–dependent IRF1 activation programs cDC1 dendritic cells to drive antitumor immunity Ghislat, G., Cheema, A. S., Baudoin, E., Verthuy, C., Ballester, P. J., Crozat, K., Attaf, N., Dong, C., Milpied, P., Malissen, B., Auphan-Anezin, N., Vu Manh, T. P., Dalod, M. & Lawrence, T., 29 Jul 2021, In: Science Immunology. 6, 61, eabg3570. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1126/sciimmunol.abg3570 Lyve-1 expressing macrophages direct the expansion of pericytes within the perivascular niche to support angiogenesis in cancer. Opzoomer, J. W., Anstee, J. E., Dean, I., Hill, E. J., Bouybayoune, I., Caron, J., Muliaditan, T., Gordon, P., Nuamah, R., Pinder, S. E., Ng, T., Dazzi, F., Kordasti, S., Withers, D. R., Lawrence, T. & Arnold, J. N., Jul 2021, In: Cancer Research. 81, 13 Research output: Contribution to journal › Meeting Abstract › peer-review PAR-1 signaling on macrophages is required for effective in vivo delayed-type hypersensitivity responses Wilkinson, H., Leonard, H., Chen, D., Lawrence, T., Robson, M., Goossens, P., McVey, JH. & Dorling, A., 22 Jan 2021, In: iScience. 24, 1, 101981. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.isci.2020.101981 Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer Etzerodt, A., Moulin, M., Doktor, T. K., Delfini, M., Mossadegh-Keller, N., Bajenoff, M., Sieweke, M. H., Moestrup, S. K., Auphan-Anezin, N. & Lawrence, T., 6 Apr 2020, In: The Journal of experimental medicine. 217, 4, e20191869. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1084/jem.20191869 Targeting stat3 and stat5 in tumor-associated immune cells to improve immunotherapy Verdeil, G., Lawrence, T., Schmitt-Verhulst, A. M. & Auphan-Anezin, N., 1 Dec 2019, In: Cancers. 11, 12, 1832. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3390/cancers11121832 Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression Etzerodt, A., Tsalkitzi, K., Maniecki, M., Damsky, W., Delfini, M., Baudoin, E., Moulin, M., Bosenberg, M., Graversen, J. H., Auphan-Anezin, N., Moestrup, S. K. & Lawrence, T., 7 Oct 2019, In: The Journal of experimental medicine. 216, 10, p. 2394-2411 18 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1084/jem.20182124 View all publications
13 September 2021 Professor Toby Lawrence joins GSK Immunology Network Professor Toby Lawrence from the School of Immunology & Microbial Sciences has been selected to join…