A highly versatile high-field NMR instrument
The 700 MHz NMR spectrometer is composed of a 16.4T superconducting magnet, a quadruple resonance (1H/13C/15N/31P) cryoprobe with z-gradients and a Bruker Avance III console. The SampleJet accessory can handle large numbers of samples in up to 49 individual tubes and five 96-well plates containing tubes of any diameter (≤ 5 mm) - the spectrometer can therefore be used for automated medium-throughput approaches such as fragment-based screening and metabolomics. This instrument can be used for a wide variety of modern, multi-dimensional structural biology experiments, and permits multi-dimensional experiments involving 31P, in addition to 13C and 15N, opening up new possibilities for the study of nucleic acids.
Wolfson Wing, Hodgkin Building Guy's Campus King’s College London London, SE1 1UL