The Gautel group aims to elucidate the mechanisms that organise sarcomeres, the smallest contractile unit of striated muscle. We investigate how sarcomeres crosstalk to mechanisms that control muscle growth or atrophy, and how muscle signalling disruptions work on the molecular level. Our studies investigate the role of mechanosensors, and why mutations in some of the proteins can lead to muscle disease.
Gautel group photo with some favourite food for thought
Our Partners
British Heart Foundation
Medical Research Council
Wellcome Trust
European Research Council
Group lead
Mathias Gautel
Professor of Molecular Cardiology