- Discovery: To dissect key biological and molecular pathways in skin diseases and understand their relevance to disease presentation, progression and treatment responses. To combine genomic investigations with pharmacological studies into the use of targeted immunological therapies.
- Translation: To develop novel therapeutic tools and diagnostic assays for both common and severe skin conditions. To identify and evaluate intervention strategies for the benefit of patients.
- Training: To focus on clinical academic training in Dermatology in collaboration with cross-cutting disciplines.
- Functional characterisation of major genetic risk regions and identification of novel genomic and proteomic markers in common skin conditions. This will provide the basis for molecular and clinical reclassification of skin diseases and identification of novel drug targets.
- Combination of genomic investigations with pharmacological studies into the use of targeted therapies. This will identify potential biomarkers for treatment response and adverse effects.
- Translation of promising preclinical research into clinical application. This will be supported by a dedicated Phase 1 and 2 Clinical Research Facility (CRF) and Skin Therapy Research Unit.
- Establishment of a skin disease biobank linking clinical information with tissue samples and translational research projects.