Muscle: Form and Function

The Muscle: Form and Function group is made up of biomedical scientists and physiologists whose research programmes range from cell and molecular biology and physiology to whole-body systems and integrative physiology. Focus is on striated (skeletal and cardiac) muscle with exercise, ageing and health as cross-cutting themes.

Research areas include:

• Physiological cardiac remodelling to improve repair and regeneration.
• The role of ageing in the regenerative capacity of the heart and skeletal muscle.
• Congenital myopathies: From mutations to treatment.
• Regulation of cardiac and skeletal muscle contractility by the thick filament in health, ageing and disease.
• The effects of healthy ageing on muscle structure and function
• The effects of critical illness on muscle
• The interaction of exercise and nutrition in regulating skeletal muscle protein turnover.