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Georgina Ellison-Hughes

Professor Georgina Ellison-Hughes

Professor of Regenerative Muscle Physiology

Research interests

  • Biomedical and life sciences

Biography

Georgina Ellison-Hughes is Professor of Regenerative Muscle Physiology and Marie Curie Fellow in the Centre of Human & Applied Physiological Sciences, King’s College London, UK. She has a BSc Sports Science (Physiology), First Class, and PhD entitled ‘Myocyte Death and Renewal in Skeletal and Cardiac Muscle’ supervised by Prof. David F. Goldspink, at Liverpool JM University, UK. She completed postdoctoral studies at New York Medical College, and Mount Sinai School of Medicine, NYC, USA. She was a post-doctoral fellow of the American Heart Association whilst training in New York, USA, 2003-2007. Her research programme focuses on understanding the biology of ageing, and in particular the role of cellular senescence, in the regeneration and repair of striated (skeletal and cardiac) muscle. Approaches include exercise training, administration of small molecule regenerative growth factors and/or stem cells, and targeting cell senescence. We have shown how targeting or modulating cell senescence improves cardiac repair and regeneration. She has made highly impactful contributions to the field establishing a world-leading track record with publications in top journals (Cell, Circ Res, Eur Heart J, Cell Research, Aging Cell).

She is a member of the UNESCO Executive committee ‘Anti-Aging and Disease Prevention’, launched in Beijing, China 2019, where together with 17 members, she contributes to promoting research and development of effective, safe and accessible anti-aging and preventive therapies to the world. During the pandemic she contributed to experimental clinical trials where mesenchymal stem/stromal cells (MSCs) were transplanted as a treatment for COVID-19 cytokine storm and ARDS.

She has delivered >45 Plenary, Invited Speaker & Session chairs at International and National conferences and is a TEDx Speaker. What becomes of the broken heartened: Rejuvenating hearts. https://youtu.be/MFjkw13A0-4

    Research

    networks2 1800 x 500 banner.
    Ellison-Hughes Group

    The group led by Dr Georgina Ellison-Hughes

    Muscle, form and function (2)
    Muscle: Form and Function

    The Muscle: Form and Function group is made up of biomedical scientists and physiologists whose research programmes range from cell and molecular biology and physiology to whole-body systems and integrative physiology

    ageing
    Centre for Ageing Resilience In a Changing Environment - CARICE

    Welcome to the Centre for Ageing Resilience in a Changing Environment: CARICE

    News

    New group of drugs found to eliminate 'zombie' cells associated with cardiovascular disease

    Researchers show that use of senolytics can improve the reparative properties of human heart cells by eliminating senescent ‘zombie cells’, known to be...

    Heart Muscle

    Novel stem cell therapy approach proves effective in treating COVID-19

    An international team of researchers has advanced a new therapeutic approach using stem cells to treat COVID-19.

    Injecting stem cells

    Boosting the search for coronavirus treatments

    King's scientists are coming together in the search for novel COVID-19 treatments.

    Coronavirus

    A new therapeutic approach improves the outcome of patients with COVID-19 pneumonia

    A new technique to improve the outcome of patients with novel coronavirus (COVID-19) pneumonia has proven safe and effective.

    coronavirus newspaper

    Events

    29Oct

    King's Experts Series: New Technologies for Mind and Body

    The mind and body have long been a source of scientific and philosophical discussion and debate. But with new technologies transforming our understanding of...

    Please note: this event has passed.

    30Nov

    Inaugural Lecture: Professors Georgina Ellison-Hughes & Ronak Rajani

    Inspiring talks from some of our brightest minds

    Please note: this event has passed.

    Features

    DDI Spotlight: 5 minutes with Georgina Ellison Hughes

    Our DDI Spotlights explore our Academic Leads for Development, Diversity and Inclusion from across the Faculty of Life Sciences & Medicine

    Guys-hero

    King's contribution to coronavirus response

    King's academics and researchers are supporting ongoing research and conversation addressing the global outbreak of novel coronavirus (COVID-19).

    Coronavirus promo

      Research

      networks2 1800 x 500 banner.
      Ellison-Hughes Group

      The group led by Dr Georgina Ellison-Hughes

      Muscle, form and function (2)
      Muscle: Form and Function

      The Muscle: Form and Function group is made up of biomedical scientists and physiologists whose research programmes range from cell and molecular biology and physiology to whole-body systems and integrative physiology

      ageing
      Centre for Ageing Resilience In a Changing Environment - CARICE

      Welcome to the Centre for Ageing Resilience in a Changing Environment: CARICE

      News

      New group of drugs found to eliminate 'zombie' cells associated with cardiovascular disease

      Researchers show that use of senolytics can improve the reparative properties of human heart cells by eliminating senescent ‘zombie cells’, known to be...

      Heart Muscle

      Novel stem cell therapy approach proves effective in treating COVID-19

      An international team of researchers has advanced a new therapeutic approach using stem cells to treat COVID-19.

      Injecting stem cells

      Boosting the search for coronavirus treatments

      King's scientists are coming together in the search for novel COVID-19 treatments.

      Coronavirus

      A new therapeutic approach improves the outcome of patients with COVID-19 pneumonia

      A new technique to improve the outcome of patients with novel coronavirus (COVID-19) pneumonia has proven safe and effective.

      coronavirus newspaper

      Events

      29Oct

      King's Experts Series: New Technologies for Mind and Body

      The mind and body have long been a source of scientific and philosophical discussion and debate. But with new technologies transforming our understanding of...

      Please note: this event has passed.

      30Nov

      Inaugural Lecture: Professors Georgina Ellison-Hughes & Ronak Rajani

      Inspiring talks from some of our brightest minds

      Please note: this event has passed.

      Features

      DDI Spotlight: 5 minutes with Georgina Ellison Hughes

      Our DDI Spotlights explore our Academic Leads for Development, Diversity and Inclusion from across the Faculty of Life Sciences & Medicine

      Guys-hero

      King's contribution to coronavirus response

      King's academics and researchers are supporting ongoing research and conversation addressing the global outbreak of novel coronavirus (COVID-19).

      Coronavirus promo