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Eamonn Reading's group focuses on understanding structure-dynamics-function relationships of membrane proteins which are important for health, with an emphasis placed on multidrug efflux systems which play a major role in bacterial antimicrobial resistance. Membrane proteins are ubiquitous biological macromolecules which reside within dynamic and highly complex cellular lipid membranes. They carry out a multitude of essential biological functions with exquisite specificity and concurrently are key targets for more than half of modern drugs. This makes understanding their fundamental processes a vital task. Our group aims to develop biological mass spectrometry and molecular biology tools capable of obtaining membrane protein structural biology information within the context of these lipid environments.

Please see the Reading Lab webpage for more information.