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This group aims to better our understanding of respiratory physiology in health & disease with the aim of improving clinical care. Through collaborative research incorporating expertise in basic, applied and clinical respiratory physiology, we aim to develop, and apply, innovative research methods to the areas of:

  • Respiratory physiology in extremes
  • Exercise physiology in health & disease
  • Impact of respiratory disease in critical care and rehabilitation

Research areas include:

  • Understanding human responses to acute and chronic respiratory stress
    • Mechanisms of respiratory failure in clinical populations
    • Regulation of human responses to hypoxia
  • Exercise limitation in health & disease
    • Respiratory muscle & breathing mechanics
    • Neurophysiology of breathlessness
  • Understanding respiratory support and monitoring
    • Chronic disease
    • Critical care
  • Cardiorespiratory interaction and control
    • Role of cardiorespiratory interaction in exercise, the effect of chronic disease and contribution to breathlessness and exercise intolerance
  • Development of new non-invasive technologies to monitor cardio-respiratory function
    • Novel analysis techniques to allow remote monitoring of pulmonary function
  • Mechanisms, monitoring and treatment of cough
  • Respiratory physiology, sleep-disordered breathing and the development of new treatments in sleep apnoea

Our Partners


National Institute for Health Research (NIHR)

The Great Britain Sasakawa Foundation

The Great Britain Sasakawa Foundation

European Comission logo

European Comission

uk space agency logo

UK Space Agency

National Institute of Academic Anaesthesia

National Institute of Academic Anaesthesia

The Engineering and Physical Sciences Research Council

The Engineering and Physical Sciences Research Council (EPSRC)

Asthma UK

Asthma UK

GSTC logo

Guy's and St Thomas' Charity

The Physiological Society logo

The Physiological Society

Group leads

Contact us

Gerrard Rafferty - Reader in Human & Translational Physiology