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We study mechanical forces controlling epithelial cell turnover. We discovered that excess epithelial cells get extruded by their neighbouring cells. Extrusion is essential for maintaining a functional barrier and we now find several deadly, yet common disease hijack this process, including metastatic cancer and asthma.

Rosenblatt Group

Publications

    Awards

    • Extrusion and Homeostasis
      National Inst. General Medical Sciences RO1 Role: Principal Investigator
    • Inhibiting bronchoconstriction-dependent airway epithelial extrusion to block the asthma inflammatory cycle American Asthma Foundation
      Role: Principal Investigator
    • Faculty Scholars Award, Howard Hughes Medical Institute Role: Principal Investigator

    Publications

      Awards

      • Extrusion and Homeostasis
        National Inst. General Medical Sciences RO1 Role: Principal Investigator
      • Inhibiting bronchoconstriction-dependent airway epithelial extrusion to block the asthma inflammatory cycle American Asthma Foundation
        Role: Principal Investigator
      • Faculty Scholars Award, Howard Hughes Medical Institute Role: Principal Investigator

      Our Partners

      American Asthma Foundation

      American Asthma Foundation

      National Institute of General Medical Sciences

      National Institute of General Medical Sciences

      Howard Hughes Medical Institute

      Howard Hughes Medical Institute