The SOUth London Diabetes (SOUL-D) study is a prospective cohort study of the association between depression and diabetes outcomes in people with newly diagnosed type 2 diabetes. It is now following patients 10-12 years after they were initially recruited.
The aim of this study is to examine a range of biological, psychological, and social factors in a group of people who have just been diagnosed with T2DM to determine their independent impact, and their interactions, on biomedical targets, quality of life, psychological functioning, and economic consequences over 10 years since diagnosis. In addition, to study whether screening for depression improves the course and outcome for depression and for diabetes, and to identify the characteristics of those most at risk for depression and for poor diabetes control.
The cohort is multi-ethic and over 1700 people with newly diagnosed type 2 diabetes were recruited at baseline. The study is now following participants up at 10+ years since baseline via face-to-face interview and medical records.
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Upsher R, Alarcon-Yaquetto DE, Stahl D, Ismail K, Winkley K. Prospective study of the association between depressive symptoms at type 2 diabetes diagnosis and time to insulin initiation in the South London diabetes (SOUL-D) cohort. Prim Care Diabetes. 2022 Jun 8:S1751-9918(22)00101-2.