Please note: this event has passed
This month we are joined by Dr Dmitry Ghilarov, Group Leader at the John Innes Centre, Norwich, who will be presenting on freeze-motion: mechanism of an ATP-powered supercoiling motor and its inhibition by new types of antibiotics revealed by cryoEM.
This seminar is part of our Molecular Biosciences@Physical of Life series sponsored by The Biochemical Society.
Speaker bio
Dr. Dmitry Ghilarov completed his graduate studies in Moscow under the supervision of Dr. Konstantin Severinov, where he studied structure & activity of a peptide antibiotic microcin B17 and related molecules. In his postdoctoral work, he has applied X-ray crystallography to determine the molecular basis of bacteriocin biosynthesis. As a Marie Curie fellow hosted by Dr. Jonathan Heddle in Krakow, he used cryo-EM to determine the molecular details of transmissible resistance to fluoroquinolone antibiotics caused by proteinaceous topoisomerase-interacting factors. He is now a Sir Henry Dale Fellow and a group leader at the John Innes Centre, Norwich, UK. His research encompasses both biosynthesis of peptide antibiotics & mechanisms how they inhibit molecular machines in a bacterial cell.
This is a hybrid seminar, details will be released shortly.
If you have any questions please don't hesitate to contact the Centre for the Physical Science of Life team at psol@kcl.ac.uk.
Sponsored by:
Advancing molecular bioscience promoting its importance as a discipline, facilitating the sharing of knowledge and expertise, and supporting molecular bioscientists across all career stages.
Centre for the Physical Science of Life Seminar Series
The Centre for the Physical Science of Life Seminar Series is the flagship seminar series for King’s College London’s Centre for the Physical Science of Life, connecting across disciplines and building collaborations between physical and life scientists to identify and solve the most fundamental riddles underpinning life.
Every month, we host a speaker to discuss a new research idea and seek contributions from audience members during the Q&A.
About us
The Centre for the Physical Science of Life realises the transformative power of physical science in advancing understanding of the fundamental mechanisms underlying living systems across scales. The goal of our unique physical science centre is to achieve a whole-scale quantitative understanding of life using physical and mathematical principles.
Based in the Faculty of Natural, Mathematical and Engineering Sciences (NMES), the Centre coalesces expertise across our Faculty in creative fusions of natural, mathematical and engineering sciences, our ambition is to solve the fundamental challenge of modern biology; bridging the gap between current biomolecular and systems level descriptions of biological phenomena.
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Event details
Room 106 (big seminar room)Britannia House
Britannia House, 7 Trinity Street, London, SE1 1DB