Biography
Alex obtained both his MSci (2008) and PhD (2012) from the Department of Chemistry, University of Bristol. After a short postdoc there, he moved to the Department of Chemical Engineering, Imperial College London, where he was a Research Associate until 2019. During this time, he was also a Visiting Researcher, at the Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (2017 – 2018). In June 2019, Alex moved to the Department of Chemistry, King’s College London, to establish his group as a Lecturer in Chemistry.
My research is in the development of new protein-based biomaterials for non-aqueous biocatalysis. The main focus of which will enable us to move from an oil-based economy to a bio-based economy. Essentially, nature has many tools for the utilisation of biomass for the various building blocks of life. However, the processes are far too slow to be used in their current form to make the fuels, chemicals, and plastics we require for modern living. The question, which my research aims to answer, can we make biological systems more compatible with synthetic systems, such that we can fully exploit nature’s toolkit to make our own industry more sustainable and more environmentally friendly.
Specifically, my main research interests are:
- Biocatalysis in ionic liquids
- Nonaqueous enzymes
- Biophysics of proteins in unnatural environments
- Biomaterials
- Functional hybrid materials
- Protein engineering
thebrogangroup.co.uk
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Bui-le, L., Clarke, C. J., Bröhl, A., Brogan, A. P. S., Arpino, J. A. J., Polizzi, K. M. & Hallett, J. P., 6 May 2020, In : Communications Chemistry. 3, 1 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s42004-020-0302-5
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Brogan, A. P. S., 18 Nov 2019, (Accepted/In press) In : Materials Horizons. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1039/C9MH01496A
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Brogan, A. P. S., Heldman, N., Hallett, J. P. & Belcher, A. M., 15 Oct 2019, In : Chemical Communications. 55, 72, p. 10752-10755 4 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1039/C9CC04909F
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Brogan, A. P. S., Bui-le, L. & Hallett, J. P., 1 Aug 2018, In : Nature Chemistry. 10, 8, p. 859-865 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/s41557-018-0088-6
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Brogan, A. P. S. & Hallett, J. P., 2016, In : Journal of The American Chemistry Society. 138, p. 4494-4501 8 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1021/jacs.5b13425
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Brogan, A. P. S., Sessions, R. B., Perriman, A. W. & Mann, S., 1 Dec 2014, In : Journal of The American Chemistry Society. 136, 48, p. 16824-16831 8 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1021/ja507592b
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Brogan, A. P. S., Sharma, K. P., Perriman, A. W. & Mann, S., 1 Oct 2014, In : Nature Communications. 5, p. 5058 1 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1038/ncomms6058
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Sharma, K. P., Zhang, Y., Thomas, M. R., Brogan, A. P. S., Perriman, A. W. & Mann, S., 1 Sep 2014, In : The journal of physical chemistry. B. 118, p. 11573-11580 8 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1021/jp507566u
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Sharma, K. P., Bradley, K., Brogan, A. P. S., Mann, S., Perriman, A. W. & Fermin, D. J., 1 Nov 2013, In : Journal of The American Chemistry Society. 135, 49, p. 18311-18314 4 p. Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1021/ja4104606
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Brogan, A. P. S., Sharma, K. P., Perriman, A. W. & Mann, S., 1 Jul 2013, In : The journal of physical chemistry. B. 117, 28, p. 8400-8407 Research output: Contribution to journal - Article. DOIs: https://doi.org/10.1021/jp4041524