Dr Amy Beedle

Amy received her bachelor's degree in Physics with Mathematics from the University of Leeds in 2012 and an MRes in Molecular Biophysics from King’s College London in 2013. In 2018 she completed her PhD in Biophysics from King’s College London under the supervision of Sergi Garcia-Manyes, where she investigated how mechanical force alters the chemical reactivity of individual proteins using single molecule force spectroscopy approaches. Following her PhD, Amy joined the lab of Pere Roca-Cusachs at the Institute for Bioengineering of Catalonia with a Sir Henry Wellcome fellowship. Here she investigated the molecular mechanisms by which individual cells can sense and response to changes in the mechanical properties of the surrounding environment. In 2023, Amy started as a Lecturer in Biological Physics in the Biological Physics and Soft Matter Group.

Research interests

Amy’s research is focused on understanding how mechanical force drives and determines the outcome of biological processes. She is interested in addressing this problem at different biological length scales, from the single molecule level to the single- and multi-cellular systems.

• Individual protein mechanics
• Cellular mechanotransduction
• The reversibility of cellular mechanotransduction