Dr Anna Schurich Academics Supervisors Lecturer Contact details anna.schurich@kcl.ac.uk +44 (0) 20 7188 5435
Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors Muliaditan, T., Halim, L., Whilding, L. M., Draper, B., Achkova, D. Y., Kausar, F., Glover, M., Bechman, N., Arulappu, A., Sanchez, J., Flaherty, K. R., Obajdin, J., Grigoriadis, K., Antoine, P., Larcombe-Young, D., Hull, C. M., Buus, R., Gordon, P., Grigoriadis, A., Davies, D. M. & 2 others, Schurich, A. & Maher, J., 21 Dec 2021, In: Cell Reports Medicine. 2, 12, 100457. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.xcrm.2021.100457 Synergistic signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors Muliaditan, T., Halim, L., Whilding, L., Draper, B., Achkova, D., Kausar, F., Glover, M., Bechman, N., Arulappu, A., Sanchez, J., Flaherty, K. R., Obajdin, J., Grigoriadis, K., Antoine, P., Larcombe-Young, D., Hull, C., Buus, R., Gordon, P., Grigoriadis, A., Davies, D. & 2 others, Schurich, A. & Maher, J., 21 Dec 2021, (Accepted/In press) In: Cell Reports Medicine. Research output: Contribution to journal › Article › peer-review Divergent impact of glucose availability on human virus-specific and generically activated CD8 T cells Sanchez, J., Jackson, I., Flaherty, K. R., Muliaditan, T. & Schurich, A., Nov 2020, In: Metabolites. 10, 11, p. 1-18 18 p., 461. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.3390/metabo10110461 Human Liver Memory CD8+ T Cells Use Autophagy for Tissue Residence Swadling, L., Pallett, L. J., Diniz, M. O., Baker, J. M., Amin, O. E., Stegmann, K. A., Burton, A. R., Schmidt, N. M., Jeffery-smith, A., Zakeri, N., Suveizdyte, K., Froghi, F., Fusai, G., Rosenberg, W. M., Davidson, B. R., Schurich, A., Simon, A. K. & Maini, M. K., 21 Jan 2020, In: Cell Reports. 30, 3, p. 687-698.e6 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.celrep.2019.12.050 The Metabolic Profile of Tumor and Virally Infected Cells Shapes Their Microenvironment Counteracting T Cell Immunity Magalhaes, I., Yogev, O., Mattsson, J. & Schurich, A., 4 Oct 2019, In: Frontiers in Immunology. 10, 2309. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.3389/fimmu.2019.02309 T cell metabolism in chronic viral infection Pallett, L. J., Schmidt, N. & Schurich, A., 1 Aug 2019, In: Clinical & Experimental Immunology. 197, 2, p. 143-152 10 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1111/cei.13308 Metabolic regulation of CAR T cell function by the hypoxic microenvironment in solid tumors Schurich, A., Magalhaes, I. & Mattsson, J., 1 Mar 2019, In: Immunotherapy. 11, 4, p. 335-345 11 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.2217/imt-2018-0141 Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver Otano, I., Escors, D., Schurich, A., Singh, H., Robertson, F., Davidson, B. R., Fusai, G., Vargas, F. A., Tan, Z. M. D., Aw, J. Y. J., Hansi, N., Kennedy, P. T. F., Xue, S-A., Stauss, H. J., Bertoletti, A., Pavesi, A. & Maini, M. K., 7 Nov 2018, In: Molecular therapy : the journal of the American Society of Gene Therapy. 26, 11, p. 2553-2566 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1016/j.ymthe.2018.08.013 The role of IL-12/23 in T cell-related chronic inflammation: Implications of immunodeficiency and therapeutic blockade Schurich, A., Raine, C., Morris, V. & Ciurtin, C., Feb 2018, In: Rheumatology (United Kingdom). 57, 2, p. 246-254 9 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1093/rheumatology/kex186 IL-2hightissue-resident T cells in the human liver: Sentinels for hepatotropic infection Pallett, L. J., Davies, J., Colbeck, E. J., Robertson, F., Hansi, N., Easom, N. J. W., Burton, A. R., Stegmann, K. A., Schurich, A., Swadling, L., Gill, U. S., Male, V., Luong, T., Gander, A., Davidson, B. R., Kennedy, P. T. F. & Maini, M. K., 5 Jun 2017, In: Journal of Experimental Medicine. 214, 6, p. 1567-1580 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1084/jem.20162115 View all publications