Professor Catherine Shanahan Professor Catherine Shanahan Academics Supervisors Professor of Cellular Signalling Vice Dean (Development, Diversity & Inclusion). Research subject areas Cardiovascular Contact details cathy.shanahan@kcl.ac.uk +44 (0) 20 7848 5221 @scorpionsstart1
Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Shanahan, C., 2023, In: AGING CELL. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/PMID: 36433666 Lamin A precursor localizes to the Z-disc of sarcomeres in the heart and is dynamically regulated in muscle cell differentiation Brayson, D. & Shanahan, C. M., 21 Nov 2022, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 377, 1864 Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1098/rstb.2021.0490 Diseases of the Aorta and Kidney Disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference for Conference Participants, 20 Sep 2022, In: Cardiovascular Research. 118, 12, p. 2582-2595 14 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1093/cvr/cvab287 Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching Swiatlowska, P., Sit, B., Feng, Z., Marhuenda, E., Xanthis, I., Zingaro, S., Ward, M., Zhou, X., Xiao, Q., Shanahan, C., Jones, G. E., Yu, C-H. & Iskratsch, T., 15 Apr 2022, In: Science Advances. 8, 15, p. eabm3471 eabm3471. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1126/sciadv.abm3471 Notch-Rho-cGMP interaction: Common point of convergence in microvascular aging-related disease Roks, A. J. M., Cheng, C. & Shanahan, C. M., May 2021, In: Clinical Science. 135, 10, p. 1209-1212 4 p. Research output: Contribution to journal › Review article › peer-review. DOIs: https://doi.org/10.1042/CS20210288 Runx2 (Runt-Related Transcription Factor 2) Links the DNA Damage Response to Osteogenic Reprogramming and Apoptosis of Vascular Smooth Muscle Cells Cobb, A. M., Yusoff, S., Hayward, R., Ahmad, S., Sun, M., Verhulst, A., D'Haese, P. C. & Shanahan, C. M., 1 Apr 2021, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 41, 4, p. 1339-1357 19 p. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1161/ATVBAHA.120.315206 Targeting Cell Stiffness: A Paradigm Shift in the Treatment of Aortic Stiffness Cecelja, M. & Shanahan, C. M., 19 Mar 2021, In: Circulation Research. 128, 6, p. 769-771 3 p. Research output: Contribution to journal › Editorial › peer-review. DOIs: https://doi.org/10.1161/CIRCRESAHA.121.318954 Circulating uromodulin: A cytokine trap for osteoinductive inflammatory mediators in chronic kidney disease? Whitehead, M. & Shanahan, C. M., 1 Mar 2021, In: Cardiovascular Research. 117, 3, p. 651-652 2 p. Research output: Contribution to journal › Editorial › peer-review. DOIs: https://doi.org/10.1093/cvr/cvaa348 Endoplasmic reticulum stress mediates vascular smooth muscle cell calcification via increased release of Grp78- loaded extracellular vesicles Furmanik, M. & Shanahan, C., 10 Dec 2020, In: Arteriosclerosis, Thrombosis, and Vascular Biology. ATVB/2020/315506DR1. Research output: Contribution to journal › Article › peer-review. DOIs: https://doi.org/10.1161/ATVBAHA.120.315506 Runx2 links the DNA damage response to osteogenic reprogramming and apoptosis of vascular smooth muscle cells Shanahan, C., 8 Dec 2020, In: Arteriosclerosis, Thrombosis, and Vascular Biology. Research output: Contribution to journal › Article › peer-review View all publications