Dr Chloe Wong PhD Academics Supervisors Senior Lecturer in Epigenetics CEDI Lead, School of Mental Health & Psychological Sciences. Contact details chloe.wong@kcl.ac.uk @ChloeCWong Chloe Wong 02078480888
Haematopoietic stem cell-derived immune cells have reduced X chromosome inactivation skewing in systemic lupus erythematosus Cannabis use as a potential mediator between childhood adversity and first-episode psychosis: results from the EU-GEI case–control study Exploring the mediation of DNA methylation across the epigenome between childhood adversity and First Episode of Psychosis—findings from the EU-GEI study Age acquired skewed X Chromosome Inactivation is associated with adverse health outcomes in humans Can epigenetics shine a light on the biological pathways underlying major mental disorders? DNA methylation signatures of adolescent victimization: Analysis of a longitudinal monozygotic twin sample Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism Leveraging epigenetics to examine differences in developmental trajectories of social attention: A proof-of-principle study of DNA methylation in infants with older siblings with autism Patterns of reliability: Assessing the reproducibility and integrity of DNA methylation measurement Establishing a Generalized Polyepigenetic Biomarker for Tobacco Smoking Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue Integrated genetic and methylomic analyses identify shared biology between autism and autistic traits Leveraging epigenetics to examine differences in developmental trajectories of social attention: A proof-of-principle study of DNA methylation in infants with an older sibling with autism Longitudinal investigation of DNA methylation changes preceding adolescent psychotic experiences RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation Analysis of DNA Methylation in Young People: Limited Evidence for an Association Between Victimization Stress and Epigenetic Variation in Blood Characterizing genetic and environmental influences on variable DNA methylation using monozygotic and dizygotic twins DNA methylation of FKBP5 and response to exposure-based psychological therapy Prenatal immune activation alters the adult neural epigenome but can be partly stabilized by a n-3 polyunsaturated fatty acid diet Genome-wide expression and response to exposure-based psychological therapy for anxiety disorders Committed to work but vulnerable: Self-perceptions and mental health in NEET 18-year olds from a contemporary British cohort Erratum to: Variation in 5-hydroxymethylcytosine across human cortex and cerebellum [Genome Biol. 2016, 17, 27] Histone Acetylome-wide Association Study of Autism Spectrum Disorder Variation in 5-hydroxymethylcytosine across human cortex and cerebellum A role for CaV1 and calcineurin signaling in depolarization-induced changes in neuronal DNA methylation Epigenome-wide DNA methylation analysis of monozygotic twins discordant for diurnal preference HPA axis related genes and response to psychological therapies: Genetics and epigenetics Measuring adolescents’ exposure to victimization: The Environmental Risk (E-Risk) Longitudinal Twin Study Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms Methylomic markers of persistent childhood asthma: A longitudinal study of asthma discordant monozygotic twins. Methylomic trajectories across human fetal brain development Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders The PsychENCODE project Epigenomic and transcriptomic signatures of a Klinefelter syndrome (47,XXY) karyotype in the brain Genome-wide Methylomic Analysis of Monozygotic Twins Discordant for Adolescent Depression Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain Serotonin Transporter Methylation and Response to Cognitive Behaviour Therapy in Children with Anxiety Disorders A data-driven approach to preprocessing Illumina 450K methylation array data Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins Anxiety sensitivity in adolescence and young adulthood: the role of stressful life events, 5HTTLPR and their interaction A Longitudinal Twin Study of Skewed X Chromosome-Inactivation Drugs and addiction: an introduction to epigenetics Sleep Quality and Diurnal Preference in a Sample of Young Adults: Associations With 5HTTLPR, PER3, and CLOCK 3111 A longitudinal study of epigenetic variation in twins Selected summaries from the XVII World Congress of Psychiatric Genetics, San Diego, California, USA, 4-8 November 2009 Genetics of addictions: strategies for addressing heterogeneity and polygenicity of substance use disorders View all publications
2 May 2023 IoPPN researchers receive the Gottesman-Shields Prize for best PhD theses 2020-2022 Dr Olakunle Oginni and Dr Yasmin Ahmadzadeh, Social, Genetic & Developmental Psychiatry Centre…